chronic pulmonary heart disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

126 genes co-occuring with the disease chronic pulmonary heart disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.48953
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.42279
ATL3 atlastin GTPase 3 1.39739
EDN1 endothelin 1 1.14178
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.10804
G6PC3 glucose 6 phosphatase, catalytic, 3 0.979268
TGFB1 transforming growth factor, beta 1 0.965825
NPPA natriuretic peptide A 0.947435
EDNRA endothelin receptor type A 0.914315
ACVRL1 activin A receptor type II-like 1 0.864274
IGLV1-36 immunoglobulin lambda variable 1-36 0.822077
ACE angiotensin I converting enzyme 0.804436
BMP4 bone morphogenetic protein 4 0.784755
SMAD6 SMAD family member 6 0.753306
PDE5A phosphodiesterase 5A, cGMP-specific 0.70434
EXOC2 exocyst complex component 2 0.699919
IPO7 importin 7 0.694702
ADM adrenomedullin 0.692296
VWF von Willebrand factor 0.680297
BMP2 bone morphogenetic protein 2 0.67551
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.674713
CKAP4 cytoskeleton-associated protein 4 0.666358
HOXB2 homeobox B2 0.649323
HOXB6 homeobox B6 0.645375
MAP2K5 mitogen-activated protein kinase kinase 5 0.645375
THBD thrombomodulin 0.644192
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.642615
GRP gastrin-releasing peptide 0.615529
PDE9A phosphodiesterase 9A 0.5645
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.554015
NOS3 nitric oxide synthase 3 (endothelial cell) 0.550911
NCR3 natural cytotoxicity triggering receptor 3 0.535409
FBN1 fibrillin 1 0.529994
RTN4 reticulon 4 0.51919
ADCY2 adenylate cyclase 2 (brain) 0.517265
MME membrane metallo-endopeptidase 0.512264
PLAT plasminogen activator, tissue 0.506507
SMAD2 SMAD family member 2 0.498467
ERAS ES cell expressed Ras 0.498467
CALCA calcitonin-related polypeptide alpha 0.483224
F8 coagulation factor VIII, procoagulant component 0.481705
PLG plasminogen 0.481705
ADRB2 adrenoceptor beta 2, surface 0.479807
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.468819
OSTM1 osteopetrosis associated transmembrane protein 1 0.460129
KAT8 K(lysine) acetyltransferase 8 0.448441
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.443171
ACTC1 actin, alpha, cardiac muscle 1 0.440538
FNDC3A fibronectin type III domain containing 3A 0.415398
HOXA5 homeobox A5 0.398589
TGFBR3 transforming growth factor, beta receptor III 0.392257
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.392257
NPPB natriuretic peptide B 0.382594
BMP1 bone morphogenetic protein 1 0.381852
HMGB2 high mobility group box 2 0.378885
KNG1 kininogen 1 0.374068
ACTA2 actin, alpha 2, smooth muscle, aorta 0.373698
SMAD4 SMAD family member 4 0.372587
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.370368
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.368518
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.368149
CLCN7 chloride channel, voltage-sensitive 7 0.365932
LHB luteinizing hormone beta polypeptide 0.361133
GRAP2 GRB2-related adaptor protein 2 0.360764
ACVR2A activin A receptor, type IIA 0.360395
HOXB7 homeobox B7 0.359289
LIMK1 LIM domain kinase 1 0.356341
RFC2 replication factor C (activator 1) 2, 40kDa 0.344941
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.340906
BMP7 bone morphogenetic protein 7 0.332121
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.326646
PF4 platelet factor 4 0.322273
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.321545
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.318272
ACVR1 activin A receptor, type I 0.316456
PDLIM1 PDZ and LIM domain 1 0.312102
ACE2 angiotensin I converting enzyme 2 0.311377
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.307395
YME1L1 YME1-like 1 ATPase 0.301976
CCL3 chemokine (C-C motif) ligand 3 0.300894
F3 coagulation factor III (thromboplastin, tissue factor) 0.298371
DYNLT1 dynein, light chain, Tctex-type 1 0.295132
MLX MLX, MAX dimerization protein 0.295132
CFL1 cofilin 1 (non-muscle) 0.294772
FBLIM1 filamin binding LIM protein 1 0.294413
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.29118
PDGFA platelet-derived growth factor alpha polypeptide 0.290821
CYCS cytochrome c, somatic 0.286877
FLNB filamin B, beta 0.284728
MAOA monoamine oxidase A 0.284728
GZMM granzyme M (lymphocyte met-ase 1) 0.27687
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.271174
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.261952
HMGA2 high mobility group AT-hook 2 0.25983
CENPB centromere protein B, 80kDa 0.259477
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.250311
ALOX5 arachidonate 5-lipoxygenase 0.239799
SPINK5 serine peptidase inhibitor, Kazal type 5 0.231795
PTGIS prostaglandin I2 (prostacyclin) synthase 0.225229
GDF5 growth differentiation factor 5 0.222822
KLF6 Kruppel-like factor 6 0.218715
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.217352
RPSA ribosomal protein SA 0.211934
PROS1 protein S (alpha) 0.208914
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.206913
NDP Norrie disease (pseudoglioma) 0.204263
CASQ2 calsequestrin 2 (cardiac muscle) 0.204263
HTRA2 HtrA serine peptidase 2 0.201308
HLA-C major histocompatibility complex, class I, C 0.199681
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.198709
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.193285
HBA2 hemoglobin, alpha 2 0.192657
RYR2 ryanodine receptor 2 (cardiac) 0.186811
STAT5A signal transducer and activator of transcription 5A 0.18651
ECE1 endothelin converting enzyme 1 0.18621
EPHX2 epoxide hydrolase 2, cytoplasmic 0.183835
APEH acylaminoacyl-peptide hydrolase 0.178126
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.169091
STAT5B signal transducer and activator of transcription 5B 0.169091
CAV1 caveolin 1, caveolae protein, 22kDa 0.168617
BMP6 bone morphogenetic protein 6 0.167915
NONO non-POU domain containing, octamer-binding 0.166095
VIP vasoactive intestinal peptide 0.161331
REN renin 0.159302
SCARB2 scavenger receptor class B, member 2 0.141079
GYPE glycophorin E (MNS blood group) 0.141043