chronic obstructive pulmonary disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

670 genes co-occuring with the disease chronic obstructive pulmonary disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PDE4A phosphodiesterase 4A, cAMP-specific 2.33859
ELANE elastase, neutrophil expressed 2.02748
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.90195
MMP12 matrix metallopeptidase 12 1.87331
CXCL8 chemokine (C-X-C motif) ligand 8 1.7948
HDAC2 histone deacetylase 2 1.77315
CRP C-reactive protein, pentraxin-related 1.75096
FAM13A family with sequence similarity 13, member A 1.62425
MMP9 matrix metallopeptidase 9 1.60323
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.57111
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.56134
SFTPD surfactant protein D 1.52908
TNF tumor necrosis factor 1.46803
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 1.43113
CXCR2 chemokine (C-X-C motif) receptor 2 1.40176
ALB albumin 1.35594
HHIP hedgehog interacting protein 1.35463
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.28479
CLNK cytokine-dependent hematopoietic cell linker 1.28217
IL6 interleukin 6 1.28086
IL1B interleukin 1, beta 1.2717
ACE angiotensin I converting enzyme 1.26429
ADRB2 adrenoceptor beta 2, surface 1.24385
MPO myeloperoxidase 1.2382
SLPI secretory leukocyte peptidase inhibitor 1.23429
TIMP1 TIMP metallopeptidase inhibitor 1 1.23082
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.20785
CD4 CD4 molecule 1.18626
MMP1 matrix metallopeptidase 1 1.17765
ADAM33 ADAM metallopeptidase domain 33 1.17378
IREB2 iron-responsive element binding protein 2 1.17335
TGFB1 transforming growth factor, beta 1 1.16906
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.14687
PDE7A phosphodiesterase 7A 1.12277
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.12235
HMOX1 heme oxygenase 1 1.11856
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.10048
CCL2 chemokine (C-C motif) ligand 2 1.08286
ADO 2-aminoethanethiol (cysteamine) dioxygenase 1.08034
NFE2L2 nuclear factor, erythroid 2-like 2 1.0711
THSD4 thrombospondin, type I, domain containing 4 1.07026
CXCR1 chemokine (C-X-C motif) receptor 1 1.06774
GC group-specific component (vitamin D binding protein) 1.06606
CXCL10 chemokine (C-X-C motif) ligand 10 1.06354
HDAC9 histone deacetylase 9 1.06228
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.05513
CS citrate synthase 1.03704
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.03282
ICAM1 intercellular adhesion molecule 1 1.0324
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.02861
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.02819
SFTPB surfactant protein B 1.02819
CTSG cathepsin G 1.01807
COPB1 coatomer protein complex, subunit beta 1 1.01765
GSTP1 glutathione S-transferase pi 1 1.01427
PPCS phosphopantothenoylcysteine synthetase 1.00541
KL klotho 1.00372
SOD2 superoxide dismutase 2, mitochondrial 1.00161
GSTM1 glutathione S-transferase mu 1 1.00119
PDE4D phosphodiesterase 4D, cAMP-specific 0.999503
GSTCD glutathione S-transferase, C-terminal domain containing 0.990644
LEP leptin 0.983057
TLR4 toll-like receptor 4 0.980531
TLR2 toll-like receptor 2 0.967921
RNASE3 ribonuclease, RNase A family, 3 0.963728
CCDC38 coiled-coil domain containing 38 0.957868
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.95369
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.940364
FBXO32 F-box protein 32 0.922974
FN1 fibronectin 1 0.918436
MMP2 matrix metallopeptidase 2 0.916375
SIRT1 sirtuin 1 0.909787
PDE4B phosphodiesterase 4B, cAMP-specific 0.908553
SOD3 superoxide dismutase 3, extracellular 0.900335
CAT catalase 0.899924
CLCA1 chloride channel accessory 1 0.897051
CCL3 chemokine (C-C motif) ligand 3 0.896641
GSTT1 glutathione S-transferase theta 1 0.872872
GSTTP1 glutathione S-transferase theta pseudogene 1 0.872872
EDN1 endothelin 1 0.872462
MARCKS myristoylated alanine-rich protein kinase C substrate 0.870006
ETV3 ets variant 3 0.864274
NPPA natriuretic peptide A 0.86059
CXCR3 chemokine (C-X-C motif) receptor 3 0.856497
GHRL ghrelin/obestatin prepropeptide 0.851583
AGER advanced glycosylation end product-specific receptor 0.842982
IL13 interleukin 13 0.838476
SIGLEC14 sialic acid binding Ig-like lectin 14 0.833558
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.832329
MSTN myostatin 0.832329
PDE4C phosphodiesterase 4C, cAMP-specific 0.832329
MAPK14 mitogen-activated protein kinase 14 0.826178
INTS12 integrator complex subunit 12 0.826178
CTSS cathepsin S 0.820026
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.818796
HBA2 hemoglobin, alpha 2 0.816745
CCL5 chemokine (C-C motif) ligand 5 0.813873
GPX1 glutathione peroxidase 1 0.812232
ELN elastin 0.799103
TLR3 toll-like receptor 3 0.796642
TSLP thymic stromal lymphopoietin 0.794591
SPDEF SAM pointed domain containing ETS transcription factor 0.792131
GCLC glutamate-cysteine ligase, catalytic subunit 0.787213
ADRA1D adrenoceptor alpha 1D 0.786803
GSTA1 glutathione S-transferase alpha 1 0.782298
CD79A CD79a molecule, immunoglobulin-associated alpha 0.774523
GSTA3 glutathione S-transferase alpha 3 0.774114
GPX5 glutathione peroxidase 5 0.773705
GSTA2 glutathione S-transferase alpha 2 0.772479
GSTA4 glutathione S-transferase alpha 4 0.771252
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 0.770844
GPX4 glutathione peroxidase 4 0.770027
LTA4H leukotriene A4 hydrolase 0.765127
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.759824
IL32 interleukin 32 0.747204
SFTPC surfactant protein C 0.745578
NT5DC1 5'-nucleotidase domain containing 1 0.74436
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.734622
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.733001
SLIT1 slit homolog 1 (Drosophila) 0.722482
NEUROD1 neuronal differentiation 1 0.722482
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 0.722482
SPATA9 spermatogenesis associated 9 0.722482
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.720058
LTBP4 latent transforming growth factor beta binding protein 4 0.718039
A1BG alpha-1-B glycoprotein 0.711183
JUN jun proto-oncogene 0.707559
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.701526
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.701124
MARCO macrophage receptor with collagenous structure 0.699919
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.690694
COPG1 coatomer protein complex, subunit gamma 1 0.688291
AHR aryl hydrocarbon receptor 0.682693
TNNT2 troponin T type 2 (cardiac) 0.680697
EGFR epidermal growth factor receptor 0.679499
CXCL11 chemokine (C-X-C motif) ligand 11 0.673518
FBXW2 F-box and WD repeat domain containing 2 0.672324
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.671527
F2 coagulation factor II (thrombin) 0.66914
TIMP2 TIMP metallopeptidase inhibitor 2 0.667947
IL17A interleukin 17A 0.664372
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.660404
CD68 CD68 molecule 0.651298
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.650903
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.646559
PDE5A phosphodiesterase 5A, cGMP-specific 0.646165
TTR transthyretin 0.642615
PPARG peroxisome proliferator-activated receptor gamma 0.641039
ITGB8 integrin, beta 8 0.631205
RAB4B RAB4B, member RAS oncogene family 0.628457
TF transferrin 0.627672
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.624535
INS insulin 0.624535
C5AR1 complement component 5a receptor 1 0.623359
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.623359
CFDP1 craniofacial development protein 1 0.617486
MLX MLX, MAX dimerization protein 0.615529
DEFB4A defensin, beta 4A 0.614356
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.610838
ANXA5 annexin A5 0.607714
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.607323
S100A8 S100 calcium binding protein A8 0.605762
SMOX spermine oxidase 0.603811
HADH hydroxyacyl-CoA dehydrogenase 0.60342
VEGFA vascular endothelial growth factor A 0.60264
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.60225
MRPL49 mitochondrial ribosomal protein L49 0.60108
LY96 lymphocyte antigen 96 0.60069
CCR3 chemokine (C-C motif) receptor 3 0.59913
ITGB6 integrin, beta 6 0.597571
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.597181
CXCL9 chemokine (C-X-C motif) ligand 9 0.596792
TAC1 tachykinin, precursor 1 0.596012
CXCL2 chemokine (C-X-C motif) ligand 2 0.592116
KEAP1 kelch-like ECH-associated protein 1 0.590169
FOXJ1 forkhead box J1 0.588222
GPANK1 G patch domain and ankyrin repeats 1 0.587833
CELA2B chymotrypsin-like elastase family, member 2B 0.587054
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.587054
VIP vasoactive intestinal peptide 0.586276
NNMT nicotinamide N-methyltransferase 0.585887
NOS3 nitric oxide synthase 3 (endothelial cell) 0.584719
ZNHIT6 zinc finger, HIT-type containing 6 0.580439
FOXA2 forkhead box A2 0.579661
SMAD2 SMAD family member 2 0.577716
STYK1 serine/threonine/tyrosine kinase 1 0.575772
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.574217
CTSL cathepsin L 0.572662
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.570718
CCL11 chemokine (C-C motif) ligand 11 0.5645
NPS neuropeptide S 0.561781
EPHA4 EPH receptor A4 0.560227
CREM cAMP responsive element modulator 0.559839
NPPB natriuretic peptide B 0.559839
COX5A cytochrome c oxidase subunit Va 0.558285
BGLAP bone gamma-carboxyglutamate (gla) protein 0.55712
CCL20 chemokine (C-C motif) ligand 20 0.556344
LTB4R leukotriene B4 receptor 0.555568
PFKM phosphofructokinase, muscle 0.55518
RPS19BP1 ribosomal protein S19 binding protein 1 0.553627
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 0.550911
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.549359
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.546644
LBR lamin B receptor 0.545481
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.538893
LBP lipopolysaccharide binding protein 0.533475
COPA coatomer protein complex, subunit alpha 0.532701
PIGR polymeric immunoglobulin receptor 0.529994
AQP5 aquaporin 5 0.529608
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 0.52536
YME1L1 YME1-like 1 ATPase 0.521888
COMMD10 COMM domain containing 10 0.520731
PAOX polyamine oxidase (exo-N4-amino) 0.520731
DCN decorin 0.518034
CCR2 chemokine (C-C motif) receptor 2 0.518034
MYD88 myeloid differentiation primary response 88 0.517649
IGF1 insulin-like growth factor 1 (somatomedin C) 0.517265
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.51611
PI3 peptidase inhibitor 3, skin-derived 0.514956
HYKK hydroxylysine kinase 0.514186
MYOD1 myogenic differentiation 1 0.513802
CTGF connective tissue growth factor 0.513033
CCR8 chemokine (C-C motif) receptor 8 0.511112
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.507657
CPN1 carboxypeptidase N, polypeptide 1 0.507273
FOXO3 forkhead box O3 0.505356
RLN1 relaxin 1 0.502292
MFAP4 microfibrillar-associated protein 4 0.501527
IL18 interleukin 18 0.497321
DNTT DNA nucleotidylexotransferase 0.496175
MMP8 matrix metallopeptidase 8 0.496175
TICRR TOPBP1-interacting checkpoint and replication regulator 0.495029
MYRF myelin regulatory factor 0.493885
XYLT1 xylosyltransferase I 0.493503
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.49274
UBE2D1 ubiquitin-conjugating enzyme E2D 1 0.490454
REN renin 0.489691
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.488549
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.485505
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.484744
ARMC2 armadillo repeat containing 2 0.484744
MCAM melanoma cell adhesion molecule 0.483985
CAMP cathelicidin antimicrobial peptide 0.483985
EGLN2 egl-9 family hypoxia-inducible factor 2 0.483985
HMGB1 high mobility group box 1 0.481325
TSPO translocator protein (18kDa) 0.480945
CCL13 chemokine (C-C motif) ligand 13 0.478289
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.474119
MMP7 matrix metallopeptidase 7 0.474119
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.47374
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.472604
PGF placental growth factor 0.472604
GSTO2 glutathione S-transferase omega 2 0.471468
CXCL5 chemokine (C-X-C motif) ligand 5 0.469576
CHRM3 cholinergic receptor, muscarinic 3 0.466928
DNAH8 dynein, axonemal, heavy chain 8 0.466172
CMA1 chymase 1, mast cell 0.466172
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.463149
GCLM glutamate-cysteine ligase, modifier subunit 0.461639
MYOG myogenin (myogenic factor 4) 0.459373
GSR glutathione reductase 0.457109
POFUT1 protein O-fucosyltransferase 1 0.456355
FGF10 fibroblast growth factor 10 0.454847
DNAI2 dynein, axonemal, intermediate chain 2 0.452585
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.450701
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.443923
MRC1 mannose receptor, C type 1 0.442418
IL1RN interleukin 1 receptor antagonist 0.440914
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.440162
TNC tenascin C 0.440162
CD1C CD1c molecule 0.439786
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.438282
HES5 hes family bHLH transcription factor 5 0.437906
LCN1 lipocalin 1 0.436402
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.433772
ARCN1 archain 1 0.433397
EDNRA endothelin receptor type A 0.433021
MAN1C1 mannosidase, alpha, class 1C, member 1 0.43227
RGS2 regulator of G-protein signaling 2 0.430393
SMAD3 SMAD family member 3 0.430017
COPZ1 coatomer protein complex, subunit zeta 1 0.426265
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.425139
SELE selectin E 0.424765
IL10 interleukin 10 0.424765
PRTN3 proteinase 3 0.424389
CHRM1 cholinergic receptor, muscarinic 1 0.422515
LTF lactotransferrin 0.421016
SP3 Sp3 transcription factor 0.418394
PTAFR platelet-activating factor receptor 0.418394
LYZ lysozyme 0.416147
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.411283
C10ORF54 chromosome 10 open reading frame 54 0.407919
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.407919
CTRL chymotrypsin-like 0.403811
MUC2 mucin 2, oligomeric mucus/gel-forming 0.403438
HBE1 hemoglobin, epsilon 1 0.400453
FGF7 fibroblast growth factor 7 0.396353
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 0.395235
CD207 CD207 molecule, langerin 0.391513
SUMF2 sulfatase modifying factor 2 0.388166
ALOX5 arachidonate 5-lipoxygenase 0.387794
TPSG1 tryptase gamma 1 0.387423
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.384822
LAG3 lymphocyte-activation gene 3 0.384451
FOXA3 forkhead box A3 0.382966
ADM adrenomedullin 0.381481
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.38111
DEFB1 defensin, beta 1 0.380368
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene 0.378885
BTNL2 butyrophilin-like 2 0.377773
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.37555
SIGLEC8 sialic acid binding Ig-like lectin 8 0.373698
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.372958
DEFA3 defensin, alpha 3, neutrophil-specific 0.369997
KNG1 kininogen 1 0.369997
ADA adenosine deaminase 0.368518
CA3 carbonic anhydrase III 0.36704
CLCA4 chloride channel accessory 4 0.366671
CALCA calcitonin-related polypeptide alpha 0.366671
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.365193
VCAN versican 0.364824
CH25H cholesterol 25-hydroxylase 0.364824
PON1 paraoxonase 1 0.364454
TREM1 triggering receptor expressed on myeloid cells 1 0.363716
ELSPBP1 epididymal sperm binding protein 1 0.36187
SOCS3 suppressor of cytokine signaling 3 0.361502
TFAM transcription factor A, mitochondrial 0.360395
OR13H1 olfactory receptor, family 13, subfamily H, member 1 0.360026
GNLY granulysin 0.358551
CARD17 caspase recruitment domain family, member 17 0.356709
SNRPF small nuclear ribonucleoprotein polypeptide F 0.355972
C10ORF11 chromosome 10 open reading frame 11 0.354499
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.354131
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.351555
HDAC5 histone deacetylase 5 0.351187
MAPK8 mitogen-activated protein kinase 8 0.351187
HSPA4 heat shock 70kDa protein 4 0.347511
KIAA0101 KIAA0101 0.347511
GSTM3 glutathione S-transferase mu 3 (brain) 0.347144
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.34384
RGN regucalcin 0.343106
DUSP1 dual specificity phosphatase 1 0.340906
FBN1 fibrillin 1 0.338707
COMT catechol-O-methyltransferase 0.337975
SESN2 sestrin 2 0.335412
HK1 hexokinase 1 0.332487
CCL22 chemokine (C-C motif) ligand 22 0.332487
POMC proopiomelanocortin 0.331756
PDZK1IP1 PDZK1 interacting protein 1 0.329565
AMOTL1 angiomotin like 1 0.3292
MMP3 matrix metallopeptidase 3 0.328105
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.327375
AREG amphiregulin 0.32701
SFTPA1 surfactant protein A1 0.32701
CLCA2 chloride channel accessory 2 0.326281
IL4 interleukin 4 0.325552
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.320817
USO1 USO1 vesicle transport factor 0.318999
PAX7 paired box 7 0.317545
HSH2D hematopoietic SH2 domain containing 0.317545
MAF1 MAF1 homolog (S. cerevisiae) 0.317545
FBLN5 fibulin 5 0.317545
ADAM19 ADAM metallopeptidase domain 19 0.316819
MGAM maltase-glucoamylase 0.316456
CDKN2A cyclin-dependent kinase inhibitor 2A 0.313189
CSHL1 chorionic somatomammotropin hormone-like 1 0.312827
CD80 CD80 molecule 0.311739
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.309928
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.308118
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.306672
PRRC2A proline-rich coiled-coil 2A 0.305226
HIST1H4H histone cluster 1, H4h 0.304142
HIST1H4D histone cluster 1, H4d 0.304142
HIST1H4B histone cluster 1, H4b 0.304142
HIST1H4J histone cluster 1, H4j 0.304142
HIST1H4E histone cluster 1, H4e 0.304142
HIST1H4F histone cluster 1, H4f 0.304142
HIST2H4B histone cluster 2, H4b 0.304142
HIST1H4K histone cluster 1, H4k 0.304142
HIST1H4I histone cluster 1, H4i 0.304142
HIST1H4A histone cluster 1, H4a 0.304142
HIST1H4C histone cluster 1, H4c 0.304142
CHIT1 chitinase 1 (chitotriosidase) 0.30342
HIST2H4A histone cluster 2, H4a 0.30342
SRSF10 serine/arginine-rich splicing factor 10 0.303059
HIST4H4 histone cluster 4, H4 0.301615
HIST1H4L histone cluster 1, H4l 0.301615
L3MBTL3 l(3)mbt-like 3 (Drosophila) 0.301254
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 0.300533
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 0.300533
LOX lysyl oxidase 0.300173
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.297651
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.295132
GALM galactose mutarotase (aldose 1-epimerase) 0.294772
TP53 tumor protein p53 0.294772
EFS embryonal Fyn-associated substrate 0.292616
CRLF2 cytokine receptor-like factor 2 0.292257
PDZD4 PDZ domain containing 4 0.292257
PDE4DIP phosphodiesterase 4D interacting protein 0.291539
SAA4 serum amyloid A4, constitutive 0.29118
CD83 CD83 molecule 0.289744
BBS2 Bardet-Biedl syndrome 2 0.289744
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.28831
FUT2 fucosyltransferase 2 (secretor status included) 0.287952
TACR2 tachykinin receptor 2 0.286519
CCL1 chemokine (C-C motif) ligand 1 0.285802
PAQR3 progestin and adipoQ receptor family member III 0.285802
MMP10 matrix metallopeptidase 10 0.285802
FOXP3 forkhead box P3 0.285444
HDAC4 histone deacetylase 4 0.284013
BCO1 beta-carotene oxygenase 1 0.284013
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.283297
NCR3 natural cytotoxicity triggering receptor 3 0.283297
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.281868
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.281868
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.281153
H3F3B H3 histone, family 3B (H3.3B) 0.279724
H3F3A H3 histone, family 3A 0.279724
TRPM2 transient receptor potential cation channel, subfamily M, member 2 0.279724
TXN thioredoxin 0.279011
MYO1D myosin ID 0.278297
USP19 ubiquitin specific peptidase 19 0.27794
S100A9 S100 calcium binding protein A9 0.27794
IL1R1 interleukin 1 receptor, type I 0.277584
IGLL5 immunoglobulin lambda-like polypeptide 5 0.277584
TNNI3 troponin I type 3 (cardiac) 0.27687
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.274732
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.273308
NTSR1 neurotensin receptor 1 (high affinity) 0.272953
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 0.271886
PTBP3 polypyrimidine tract binding protein 3 0.271886
MARS methionyl-tRNA synthetase 0.270464
PHF13 PHD finger protein 13 0.270464
ARRB1 arrestin, beta 1 0.270108
F3 coagulation factor III (thromboplastin, tissue factor) 0.269043
CAPS calcyphosine 0.269043
STAT1 signal transducer and activator of transcription 1, 91kDa 0.269043
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.268687
PNOC prepronociceptin 0.267622
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.266913
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.266203
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.265494
CST2 cystatin SA 0.265494
EGR1 early growth response 1 0.264785
EPRS glutamyl-prolyl-tRNA synthetase 0.264431
MMP23B matrix metallopeptidase 23B 0.263722
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.260538
BGN biglycan 0.260184
CREB1 cAMP responsive element binding protein 1 0.25983
CXCL13 chemokine (C-X-C motif) ligand 13 0.259124
WNT5B wingless-type MMTV integration site family, member 5B 0.259124
LIPE lipase, hormone-sensitive 0.258417
MAPK3 mitogen-activated protein kinase 3 0.255946
FGF2 fibroblast growth factor 2 (basic) 0.254183
BAX BCL2-associated X protein 0.253831
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.253479
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.253127
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.252774
CD69 CD69 molecule 0.25207
CPB1 carboxypeptidase B1 (tissue) 0.251718
NLRC5 NLR family, CARD domain containing 5 0.251366
VWF von Willebrand factor 0.24996
TSPYL4 TSPY-like 4 0.249608
PLA2G2D phospholipase A2, group IID 0.249257
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.249257
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.248554
FLNA filamin A, alpha 0.248203
FPR2 formyl peptide receptor 2 0.246448
EPX eosinophil peroxidase 0.246098
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.245747
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.244345
FGF23 fibroblast growth factor 23 0.243645
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.243295
IL9 interleukin 9 0.241546
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.240847
TTC3 tetratricopeptide repeat domain 3 0.239101
B3GNT1 0.238752
ALPPL2 alkaline phosphatase, placental-like 2 0.238752
MYF6 myogenic factor 6 (herculin) 0.238403
ALPP alkaline phosphatase, placental 0.238403
ALPL alkaline phosphatase, liver/bone/kidney 0.237706
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.236312
IL16 interleukin 16 0.235616
ADAM17 ADAM metallopeptidase domain 17 0.235268
CST4 cystatin S 0.234573
PER1 period circadian clock 1 0.234573
ANG angiogenin, ribonuclease, RNase A family, 5 0.234225
SIRT4 sirtuin 4 0.23353
MB myoglobin 0.232142
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.231795
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.231448
BPI bactericidal/permeability-increasing protein 0.230409
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.229716
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.229024
BRD2 bromodomain containing 2 0.229024
NOTCH1 notch 1 0.227642
PELI1 pellino E3 ubiquitin protein ligase 1 0.227297
MYF5 myogenic factor 5 0.227297
TACR1 tachykinin receptor 1 0.226952
SRXN1 sulfiredoxin 1 0.226952
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 0.226952
NOS2 nitric oxide synthase 2, inducible 0.226952
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.226607
HDAC1 histone deacetylase 1 0.226607
SOX5 SRY (sex determining region Y)-box 5 0.225917
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.225229
LTA lymphotoxin alpha 0.224884
CP ceruloplasmin (ferroxidase) 0.224884
LCN2 lipocalin 2 0.224196
ENO1 enolase 1, (alpha) 0.222822
BICD1 bicaudal D homolog 1 (Drosophila) 0.222136
SMAD7 SMAD family member 7 0.222136
CD1D CD1d molecule 0.221793
GPR65 G protein-coupled receptor 65 0.22145
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.220081
ENOSF1 enolase superfamily member 1 0.21974
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.218715
SIRT2 sirtuin 2 0.218715
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.218374
HAND1 heart and neural crest derivatives expressed 1 0.217012
ANKRD54 ankyrin repeat domain 54 0.216672
KLK15 kallikrein-related peptidase 15 0.216332
BAG6 BCL2-associated athanogene 6 0.215653
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.214975
CHRDL1 chordin-like 1 0.214297
BPIFA1 BPI fold containing family A, member 1 0.213959
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.213621
SAMD11 sterile alpha motif domain containing 11 0.212608
ATF6 activating transcription factor 6 0.210925
ERRFI1 ERBB receptor feedback inhibitor 1 0.209918
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.209583
HSPE1 heat shock 10kDa protein 1 0.208579
HSPA1L heat shock 70kDa protein 1-like 0.208245
ESPN espin 0.207912
ADGRG3 adhesion G protein-coupled receptor G3 0.207912
SMAD4 SMAD family member 4 0.207245
COL6A5 collagen, type VI, alpha 5 0.207245
LAX1 lymphocyte transmembrane adaptor 1 0.206913
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.20658
PEX10 peroxisomal biogenesis factor 10 0.206248
PLEK2 pleckstrin 2 0.204593
FPR1 formyl peptide receptor 1 0.204593
ANAPC5 anaphase promoting complex subunit 5 0.20229
MGST3 microsomal glutathione S-transferase 3 0.201962
ADORA2B adenosine A2b receptor 0.201308
MAEA macrophage erythroblast attacher 0.201308
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.200982
PTGDR2 prostaglandin D2 receptor 2 0.200656
IL12A interleukin 12A 0.200656
PRF1 perforin 1 (pore forming protein) 0.199681
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 0.199033
ARRB2 arrestin, beta 2 0.198709
HPX hemopexin 0.19742
ADCY2 adenylate cyclase 2 (brain) 0.196779
ACE2 angiotensin I converting enzyme 2 0.19582
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.19582
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.195501
CER1 cerberus 1, DAN family BMP antagonist 0.195183
MAP2K3 mitogen-activated protein kinase kinase 3 0.193915
NPNT nephronectin 0.192971
NLRP3 NLR family, pyrin domain containing 3 0.192657
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.192344
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.191719
CD276 CD276 molecule 0.191719
SIRT6 sirtuin 6 0.191408
HYAL2 hyaluronoglucosaminidase 2 0.191097
PCNA proliferating cell nuclear antigen 0.190786
TLR1 toll-like receptor 1 0.190476
LEMD1 LEM domain containing 1 0.190168
NOX3 NADPH oxidase 3 0.190168
LEPR leptin receptor 0.189859
PEF1 penta-EF-hand domain containing 1 0.189244
MMP25 matrix metallopeptidase 25 0.188632
BECN1 beclin 1, autophagy related 0.187719
PTGIS prostaglandin I2 (prostacyclin) synthase 0.187415
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.18621
FTL ferritin, light polypeptide 0.185612
CCR6 chemokine (C-C motif) receptor 6 0.185016
TLR6 toll-like receptor 6 0.183835
ESAM endothelial cell adhesion molecule 0.183248
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.182666
FLNC filamin C, gamma 0.182086
CD34 CD34 molecule 0.181798
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.180937
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.179239
FOXP4 forkhead box P4 0.17896
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.17896
ATF4 activating transcription factor 4 0.177851
FBXL20 F-box and leucine-rich repeat protein 20 0.177576
SAA1 serum amyloid A1 0.176485
SCARB2 scavenger receptor class B, member 2 0.176215
FRRS1L ferric-chelate reductase 1-like 0.175679
LTB lymphotoxin beta (TNF superfamily, member 3) 0.175411
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.175146
EI24 etoposide induced 2.4 0.173571
BANF1 barrier to autointegration factor 1 0.173057
MAP4 microtubule-associated protein 4 0.172544
KDR kinase insert domain receptor 0.172291
FOXO1 forkhead box O1 0.171535
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.171535
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.171036
CD86 CD86 molecule 0.169812
HBA1 hemoglobin, alpha 1 0.169812
PI15 peptidase inhibitor 15 0.169571
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.16933
C6ORF25 chromosome 6 open reading frame 25 0.16933
OLFM1 olfactomedin 1 0.168617
FOXP1 forkhead box P1 0.167915
PPAP2B phosphatidic acid phosphatase type 2B 0.167224
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.166995
IRF7 interferon regulatory factor 7 0.165874
SMAD6 SMAD family member 6 0.165874
CD36 CD36 molecule (thrombospondin receptor) 0.165874
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 0.165001
MDS2 myelodysplastic syndrome 2 translocation associated 0.164786
PTH parathyroid hormone 0.162505
TGFBR3 transforming growth factor, beta receptor III 0.162306
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.162109
ODF1 outer dense fiber of sperm tails 1 0.161331
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.161139
CD40 CD40 molecule, TNF receptor superfamily member 5 0.160761
FTH1 ferritin, heavy polypeptide 1 0.159302
HOXD8 homeobox D8 0.158951
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.158778
CFAP74 cilia and flagella associated protein 74 0.158605
OXR1 oxidation resistance 1 0.157929
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.157929
FLT1 fms-related tyrosine kinase 1 0.143911
IL2RA interleukin 2 receptor, alpha 0.143575
MUC1 mucin 1, cell surface associated 0.143571
PROX1 prospero homeobox 1 0.143551
NELFCD negative elongation factor complex member C/D 0.142832
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.140803
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.140193
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.139751
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.139449
ZNF79 zinc finger protein 79 0.138061
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.137668
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.137581
PLAGL2 pleiomorphic adenoma gene-like 2 0.137102
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.136378
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.135846
WWTR1 WW domain containing transcription regulator 1 0.135383
GUSB glucuronidase, beta 0.134615
MAN2B1 mannosidase, alpha, class 2B, member 1 0.134576
CDT1 chromatin licensing and DNA replication factor 1 0.1345
DYNLL1 dynein, light chain, LC8-type 1 0.133842
MSRA methionine sulfoxide reductase A 0.133603
ALYREF Aly/REF export factor 0.133473
CELA1 chymotrypsin-like elastase family, member 1 0.133444
BLVRA biliverdin reductase A 0.133088
CTSE cathepsin E 0.13264
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.132367
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.131555
WDFY2 WD repeat and FYVE domain containing 2 0.130674
PLCH2 phospholipase C, eta 2 0.130344
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.129334
CRABP1 cellular retinoic acid binding protein 1 0.129182
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.129138
GPX2 glutathione peroxidase 2 0.128371
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.127678
PRDM2 PR domain containing 2, with ZNF domain 0.127229
CRABP2 cellular retinoic acid binding protein 2 0.126658
AZU1 azurocidin 1 0.126228
CADM1 cell adhesion molecule 1 0.124554
CDC6 cell division cycle 6 0.123776
ABHD2 abhydrolase domain containing 2 0.123615
ECI1 enoyl-CoA delta isomerase 1 0.123321
DNM1L dynamin 1-like 0.122788
HRAS Harvey rat sarcoma viral oncogene homolog 0.117891