chromosome passenger complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin. (Gene Ontology, GO_0032133)
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70 proteins co-occuring with the chromosome passenger complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
INCENP inner centromere protein antigens 135/155kDa 3.16274
AURKB aurora kinase B 3.0027
CDCA8 cell division cycle associated 8 2.80868
BIRC5 baculoviral IAP repeat containing 5 2.55479
AURKC aurora kinase C 1.44742
KLHL13 kelch-like family member 13 1.27027
KLHL9 kelch-like family member 9 1.26339
KIF23 kinesin family member 23 1.2148
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 1.1844
H3F3B H3 histone, family 3B (H3.3B) 1.17978
H3F3A H3 histone, family 3A 1.17978
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.03228
SGOL1 shugoshin-like 1 (S. pombe) 1.02131
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.980016
KIF20A kinesin family member 20A 0.894868
PLK1 polo-like kinase 1 0.83781
CENPE centromere protein E, 312kDa 0.772732
CDK1 cyclin-dependent kinase 1 0.770907
KIF2C kinesin family member 2C 0.744574
TPX2 TPX2, microtubule-associated 0.739614
CENPA centromere protein A 0.720351
CHMP4C charged multivesicular body protein 4C 0.720351
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.70439
STK31 serine/threonine kinase 31 0.69427
KLK12 kallikrein-related peptidase 12 0.691202
SGOL2 shugoshin-like 2 (S. pombe) 0.682463
CENPC centromere protein C 0.655172
KLHL22 kelch-like family member 22 0.640573
GAS2L3 growth arrest-specific 2 like 3 0.599802
PRC1 protein regulator of cytokinesis 1 0.578416
GTPBP4 GTP binding protein 4 0.565508
RAD21 RAD21 homolog (S. pombe) 0.543587
CUL3 cullin 3 0.503912
RCC2 regulator of chromosome condensation 2 0.499447
IL20RA interleukin 20 receptor, alpha 0.460001
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.450836
KIF2A kinesin heavy chain member 2A 0.45004
XPO1 exportin 1 0.447259
KLHL21 kelch-like family member 21 0.43538
RBBP7 retinoblastoma binding protein 7 0.42082
NUF2 NUF2, NDC80 kinetochore complex component 0.41612
SPATA5 spermatogenesis associated 5 0.398199
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.37697
CDC14A cell division cycle 14A 0.376586
KIF4A kinesin family member 4A 0.363567
EVI5 ecotropic viral integration site 5 0.357467
KMT2E lysine (K)-specific methyltransferase 2E 0.343799
OTP orthopedia homeobox 0.339261
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.329084
NSL1 NSL1, MIS12 kinetochore complex component 0.321201
SEH1L SEH1-like (S. cerevisiae) 0.297713
ZNF135 zinc finger protein 135 0.293267
CKAP5 cytoskeleton associated protein 5 0.277406
RIC8A RIC8 guanine nucleotide exchange factor A 0.275202
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.266408
APITD1 apoptosis-inducing, TAF9-like domain 1 0.265677
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.236683
HJURP Holliday junction recognition protein 0.21646
AJUBA ajuba LIM protein 0.215761
CENPT centromere protein T 0.21124
KIF15 kinesin family member 15 0.210894
STIL SCL/TAL1 interrupting locus 0.209513
FHOD1 formin homology 2 domain containing 1 0.190495
CENPB centromere protein B, 80kDa 0.179752
PLK3 polo-like kinase 3 0.177439
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.174911
KIFC1 kinesin family member C1 0.167856
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.159856
HMGN2 high mobility group nucleosomal binding domain 2 0.159268
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.158692