chromosome, telomeric region Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins. (Gene Ontology, GO_0000781)
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197 proteins co-occuring with the chromosome, telomeric region cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 2.86225
TERT telomerase reverse transcriptase 2.70369
POT1 protection of telomeres 1 2.54069
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.46482
TERF2 telomeric repeat binding factor 2 1.77144
ATM ATM serine/threonine kinase 1.75275
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1.57875
DKC1 dyskeratosis congenita 1, dyskerin 1.49944
TP53 tumor protein p53 1.38073
CTC1 CTS telomere maintenance complex component 1 1.36913
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.35978
NOP10 NOP10 ribonucleoprotein 1.35758
NHP2 NHP2 ribonucleoprotein 1.2921
WRN Werner syndrome, RecQ helicase-like 1.27346
H2AFX H2A histone family, member X 1.18492
RAD50 RAD50 homolog (S. cerevisiae) 1.16594
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.10919
TERF2IP telomeric repeat binding factor 2, interacting protein 1.10562
RTEL1 regulator of telomere elongation helicase 1 1.05287
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 1.02779
CDKN2A cyclin-dependent kinase inhibitor 2A 1.00596
EXO1 exonuclease 1 0.997104
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.977104
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.972747
ACD adrenocortical dysplasia homolog (mouse) 0.940215
MYB v-myb avian myeloblastosis viral oncogene homolog 0.870426
GAR1 GAR1 ribonucleoprotein 0.794687
RAD52 RAD52 homolog (S. cerevisiae) 0.771819
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.768627
SMG6 SMG6 nonsense mediated mRNA decay factor 0.747285
LIG4 ligase IV, DNA, ATP-dependent 0.746833
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.706156
CCDC79 coiled-coil domain containing 79 0.676803
ATR ATR serine/threonine kinase 0.670725
USB1 U6 snRNA biogenesis 1 0.669425
MIR186 microRNA 186 0.661208
CLPTM1L CLPTM1-like 0.65905
HIST1H4H histone cluster 1, H4h 0.647003
HIST1H4I histone cluster 1, H4i 0.647003
HIST1H4J histone cluster 1, H4j 0.647003
HIST1H4K histone cluster 1, H4k 0.647003
HIST1H4D histone cluster 1, H4d 0.647003
HIST1H4E histone cluster 1, H4e 0.647003
HIST2H4B histone cluster 2, H4b 0.647003
HIST1H4A histone cluster 1, H4a 0.647003
HIST1H4B histone cluster 1, H4b 0.647003
HIST1H4C histone cluster 1, H4c 0.647003
HIST4H4 histone cluster 4, H4 0.646574
HIST2H4A histone cluster 2, H4a 0.646574
HIST1H4F histone cluster 1, H4f 0.646574
HIST1H4L histone cluster 1, H4l 0.646574
RECQL5 RecQ protein-like 5 0.641858
TP53BP1 tumor protein p53 binding protein 1 0.62393
ORC1 origin recognition complex, subunit 1 0.611625
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 0.593912
C9ORF78 chromosome 9 open reading frame 78 0.593912
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.592652
ERCC4 excision repair cross-complementation group 4 0.570496
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.568416
PARP1 poly (ADP-ribose) polymerase 1 0.557629
ZNF827 zinc finger protein 827 0.54771
TEP1 telomerase-associated protein 1 0.538238
MTRF1 mitochondrial translational release factor 1 0.537416
MORF4L2 mortality factor 4 like 2 0.530028
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.52675
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.521432
GLB1 galactosidase, beta 1 0.521023
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.50107
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.496205
H3F3B H3 histone, family 3B (H3.3B) 0.486904
H3F3A H3 histone, family 3A 0.486904
MEN1 multiple endocrine neoplasia I 0.484886
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.477636
BRCA2 breast cancer 2, early onset 0.474822
CHEK1 checkpoint kinase 1 0.466399
PIF1 PIF1 5'-to-3' DNA helicase 0.465998
EME2 essential meiotic structure-specific endonuclease subunit 2 0.463198
RB1 retinoblastoma 1 0.446465
SRRT serrate, RNA effector molecule 0.438542
CD4 CD4 molecule 0.434591
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.428284
ZSCAN4 zinc finger and SCAN domain containing 4 0.425924
SPO11 SPO11 meiotic protein covalently bound to DSB 0.425924
NDRG1 N-myc downstream regulated 1 0.423174
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.41143
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.405193
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.404026
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.39471
CGGBP1 CGG triplet repeat binding protein 1 0.392001
DNA2 DNA replication helicase/nuclease 2 0.385436
ATRIP ATR interacting protein 0.377738
TRIP6 thyroid hormone receptor interactor 6 0.373132
STAG1 stromal antigen 1 0.368153
RFC3 replication factor C (activator 1) 3, 38kDa 0.365477
BRCA1 breast cancer 1, early onset 0.363949
IGH immunoglobulin heavy locus 0.351762
SLX4 SLX4 structure-specific endonuclease subunit 0.349484
RAD9A RAD9 homolog A (S. pombe) 0.347208
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.344178
HIST1H2BH histone cluster 1, H2bh 0.343421
HIST2H2BF histone cluster 2, H2bf 0.343421
HIST3H2BB histone cluster 3, H2bb 0.343421
HIST1H2BD histone cluster 1, H2bd 0.343042
HIST1H2BC histone cluster 1, H2bc 0.341529
HRAS Harvey rat sarcoma viral oncogene homolog 0.341529
HIST1H2BF histone cluster 1, H2bf 0.341529
HIST1H2BA histone cluster 1, H2ba 0.340395
SYCP3 synaptonemal complex protein 3 0.338884
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.325327
HMBOX1 homeobox containing 1 0.323825
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 0.321201
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.319328
PTER phosphotriesterase related 0.311478
MLH1 mutL homolog 1 0.310358
MKRN1 makorin ring finger protein 1 0.308867
MDC1 mediator of DNA-damage checkpoint 1 0.306632
RECQL4 RecQ protein-like 4 0.302912
AHSG alpha-2-HS-glycoprotein 0.301797
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.299197
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.298455
PARP2 poly (ADP-ribose) polymerase 2 0.293267
RLIM ring finger protein, LIM domain interacting 0.290308
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.289199
NBN nibrin 0.28846
FEN1 flap structure-specific endonuclease 1 0.288091
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 0.287352
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.286983
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.286614
KRAS Kirsten rat sarcoma viral oncogene homolog 0.278509
MIR96 microRNA 96 0.268603
RAD17 RAD17 homolog (S. pombe) 0.267871
HIRA histone cell cycle regulator 0.264581
LPP LIM domain containing preferred translocation partner in lipoma 0.260202
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.259837
ZC3H12D zinc finger CCCH-type containing 12D 0.257652
ABRA actin binding Rho activating protein 0.257652
GSTZ1 glutathione S-transferase zeta 1 0.253653
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.246046
ZSCAN1 zinc finger and SCAN domain containing 1 0.246046
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.234174
RFC4 replication factor C (activator 1) 4, 37kDa 0.233101
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 0.231672
FRG1 FSHD region gene 1 0.231315
USP22 ubiquitin specific peptidase 22 0.22279
SIRT1 sirtuin 1 0.219969
RFC1 replication factor C (activator 1) 1, 145kDa 0.215761
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.21124
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.210894
PARP3 poly (ADP-ribose) polymerase family, member 3 0.209513
OGG1 8-oxoguanine DNA glycosylase 0.205059
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.204039
RAD51 RAD51 recombinase 0.1921
MTBP MDM2 binding protein 0.191777
RFC2 replication factor C (activator 1) 2, 40kDa 0.189539
MUS81 MUS81 structure-specific endonuclease subunit 0.187333
CD34 CD34 molecule 0.183025
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.182422
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.182422
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.182422
DAXX death-domain associated protein 0.181823
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.18093
DCLRE1C DNA cross-link repair 1C 0.179752
MSH2 mutS homolog 2 0.17687
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.175188
NMUR2 neuromedin U receptor 2 0.170629
FRMD6 FERM domain containing 6 0.166884
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.166643
FANCD2 Fanconi anemia, complementation group D2 0.164315
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.164089
DUX4L8 double homeobox 4 like 8 0.16342
MZF1 myeloid zinc finger 1 0.16342
EIF3C eukaryotic translation initiation factor 3, subunit C 0.16233
MTUS1 microtubule associated tumor suppressor 1 0.161484
FSTL3 follistatin-like 3 (secreted glycoprotein) 0.160863
ASPH aspartate beta-hydroxylase 0.160863
RANBP9 RAN binding protein 9 0.157218
TPSG1 tryptase gamma 1 0.143257
SMN1 survival of motor neuron 1, telomeric 0.143173
RAD54B RAD54 homolog B (S. cerevisiae) 0.143015
COPS2 COP9 signalosome subunit 2 0.142809
MRI1 methylthioribose-1-phosphate isomerase 1 0.142621
PARK2 parkin RBR E3 ubiquitin protein ligase 0.142568
BOLL boule-like RNA-binding protein 0.142517
SIAH2 siah E3 ubiquitin protein ligase 2 0.142497
SNW1 SNW domain containing 1 0.141727
RECQL RecQ helicase-like 0.141664
SMN2 survival of motor neuron 2, centromeric 0.140995
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.13981
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.139466
TFR2 transferrin receptor 2 0.139445
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.139025
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.138958
MCM6 minichromosome maintenance complex component 6 0.138913
TIMELESS timeless circadian clock 0.138753
SIAH1 siah E3 ubiquitin protein ligase 1 0.138433
TPP1 tripeptidyl peptidase I 0.13736
SUN1 Sad1 and UNC84 domain containing 1 0.136819