chromatin silencing Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. (Gene Ontology, GO_0006342)
External Link http://amigo.geneontology.org/amigo/term/GO:0006342
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Genes

27 genes participating in the chromatin silencing biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
BAHD1 bromo adjacent homology domain containing 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOT1L DOT1-like histone H3K79 methyltransferase
HAT1 histone acetyltransferase 1
HDAC5 histone deacetylase 5
HELLS helicase, lymphoid-specific
KMT2D lysine (K)-specific methyltransferase 2D
MBD3 methyl-CpG binding domain protein 3
MECP2 methyl CpG binding protein 2
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SIRT4 sirtuin 4
SIRT5 sirtuin 5
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
TBP TATA box binding protein
TNP1 transition protein 1 (during histone to protamine replacement)
TNRC18 trinucleotide repeat containing 18
UBR2 ubiquitin protein ligase E3 component n-recognin 2