cholesterol metabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues. (Gene Ontology, GO_0008203)
External Link http://amigo.geneontology.org/amigo/term/GO:0008203
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Genes

106 genes participating in the cholesterol metabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACAA2 acetyl-CoA acyltransferase 2
AKR1D1 aldo-keto reductase family 1, member D1
ANGPTL3 angiopoietin-like 3
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOBR apolipoprotein B receptor
APOC1 apolipoprotein C-I
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOF apolipoprotein F
APOL1 apolipoprotein L, 1
APOL2 apolipoprotein L, 2
APP amyloid beta (A4) precursor protein
CAT catalase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CELA3A chymotrypsin-like elastase family, member 3A
CELA3B chymotrypsin-like elastase family, member 3B
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CH25H cholesterol 25-hydroxylase
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNBP CCHC-type zinc finger, nucleic acid binding protein
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYB5R3 cytochrome b5 reductase 3
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FDX1 ferredoxin 1
FDXR ferredoxin reductase
FECH ferrochelatase
FGL1 fibrinogen-like 1
G6PD glucose-6-phosphate dehydrogenase
GGPS1 geranylgeranyl diphosphate synthase 1
HDLBP high density lipoprotein binding protein
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
IDI2 isopentenyl-diphosphate delta isomerase 2
IL4 interleukin 4
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
LBR lamin B receptor
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LEP leptin
LEPR leptin receptor
LIPC lipase, hepatic
LIPE lipase, hormone-sensitive
LRP1 low density lipoprotein receptor-related protein 1
LRP5 low density lipoprotein receptor-related protein 5
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MSMO1 methylsterol monooxygenase 1
MT3 metallothionein 3
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NPC1 Niemann-Pick disease, type C1
NPC1L1 NPC1-like 1
NPC2 Niemann-Pick disease, type C2
NR0B2 nuclear receptor subfamily 0, group B, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
OSBPL1A oxysterol binding protein-like 1A
OSBPL5 oxysterol binding protein-like 5
PCSK9 proprotein convertase subtilisin/kexin type 9
PCTP phosphatidylcholine transfer protein
PMVK phosphomevalonate kinase
PPARD peroxisome proliferator-activated receptor delta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
RXRA retinoid X receptor, alpha
SC5D sterol-C5-desaturase
SCAP SREBF chaperone
SCARB1 scavenger receptor class B, member 1
SCARF1 scavenger receptor class F, member 1
SNX17 sorting nexin 17
SOAT1 sterol O-acyltransferase 1
SOAT2 sterol O-acyltransferase 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SQLE squalene epoxidase
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
STAR steroidogenic acute regulatory protein
STARD3 StAR-related lipid transfer (START) domain containing 3
TM7SF2 transmembrane 7 superfamily member 2
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRERF1 transcriptional regulating factor 1
VLDLR very low density lipoprotein receptor