cholesterol biosynthetic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. (Gene Ontology, GO_0006695)
External Link http://amigo.geneontology.org/amigo/term/GO:0006695
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Genes

35 genes participating in the cholesterol biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CNBP CCHC-type zinc finger, nucleic acid binding protein
CYB5R3 cytochrome b5 reductase 3
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
G6PD glucose-6-phosphate dehydrogenase
GGPS1 geranylgeranyl diphosphate synthase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
IDI2 isopentenyl-diphosphate delta isomerase 2
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
LBR lamin B receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NPC1L1 NPC1-like 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PMVK phosphomevalonate kinase
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
SC5D sterol-C5-desaturase
SQLE squalene epoxidase
TM7SF2 transmembrane 7 superfamily member 2