chloropyramine-4589 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the chloropyramine-4589 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALK anaplastic lymphoma receptor tyrosine kinase
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
BIRC3 baculoviral IAP repeat containing 3
BMP4 bone morphogenetic protein 4
BTF3P11 basic transcription factor 3 pseudogene 11
C10ORF10 chromosome 10 open reading frame 10
C11ORF16 chromosome 11 open reading frame 16
C1ORF106 chromosome 1 open reading frame 106
C1ORF116 chromosome 1 open reading frame 116
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPN3 calpain 3, (p94)
CCDC85B coiled-coil domain containing 85B
CD82 CD82 molecule
CDRT1 CMT1A duplicated region transcript 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLIC2 chloride intracellular channel 2
CREM cAMP responsive element modulator
CRYGC crystallin, gamma C
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DMP1 dentin matrix acidic phosphoprotein 1
EDN1 endothelin 1
EGR2 early growth response 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
GLS2 glutaminase 2 (liver, mitochondrial)
GPR27 G protein-coupled receptor 27
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRIP2 glutamate receptor interacting protein 2
HEMK1 HemK methyltransferase family member 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ICAM1 intercellular adhesion molecule 1
IFIH1 interferon induced with helicase C domain 1
IL6 interleukin 6
INF2 inverted formin, FH2 and WH2 domain containing
INHBA inhibin, beta A
INO80D INO80 complex subunit D
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KLF3 Kruppel-like factor 3 (basic)
LAMC2 laminin, gamma 2
LRRK1 leucine-rich repeat kinase 1
LTBP4 latent transforming growth factor beta binding protein 4
MAU2 MAU2 sister chromatid cohesion factor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPL41 mitochondrial ribosomal protein L41
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NOTCH4 notch 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAX2 paired box 2
PAX8 paired box 8
PCDH11Y protocadherin 11 Y-linked
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PDIA4 protein disulfide isomerase family A, member 4
PDLIM5 PDZ and LIM domain 5
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAG1 pleiomorphic adenoma gene 1
PRDM1 PR domain containing 1, with ZNF domain
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRH protein tyrosine phosphatase, receptor type, H
PTX3 pentraxin 3, long
RAB28 RAB28, member RAS oncogene family
RASAL2 RAS protein activator like 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPS3A ribosomal protein S3A
RUNDC3B RUN domain containing 3B
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SAMD4A sterile alpha motif domain containing 4A
SCN9A sodium channel, voltage gated, type IX alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP5 secreted frizzled-related protein 5
SMR3A submaxillary gland androgen regulated protein 3A
SPRR2B small proline-rich protein 2B
SRD5A3 steroid 5 alpha-reductase 3
SULF1 sulfatase 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAS2R10 taste receptor, type 2, member 10
TEX15 testis expressed 15
TGFB2 transforming growth factor, beta 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
TRIO trio Rho guanine nucleotide exchange factor
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM15 ADAM metallopeptidase domain 15
ADGRB2 adhesion G protein-coupled receptor B2
AGMAT agmatine ureohydrolase (agmatinase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD36 ankyrin repeat domain 36
APOLD1 apolipoprotein L domain containing 1
ARHGAP24 Rho GTPase activating protein 24
ATP10D ATPase, class V, type 10D
BEND5 BEN domain containing 5
BTD biotinidase
C14ORF93 chromosome 14 open reading frame 93
C3 complement component 3
CARD8 caspase recruitment domain family, member 8
CCDC85C coiled-coil domain containing 85C
CEL carboxyl ester lipase
CIDEC cell death-inducing DFFA-like effector c
CPNE7 copine VII
CPZ carboxypeptidase Z
DEPTOR DEP domain containing MTOR-interacting protein
EHF ets homologous factor
ELOVL4 ELOVL fatty acid elongase 4
ELSPBP1 epididymal sperm binding protein 1
ERCC5 excision repair cross-complementation group 5
FAM105A family with sequence similarity 105, member A
FAM118A family with sequence similarity 118, member A
FAM131B family with sequence similarity 131, member B
FBXO2 F-box protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FOXA1 forkhead box A1
GALK1 galactokinase 1
GLB1L galactosidase, beta 1-like
GPX2 glutathione peroxidase 2
GRAMD1C GRAM domain containing 1C
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H1F0 H1 histone family, member 0
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H4E histone cluster 1, H4e
HOXA1 homeobox A1
IFI44L interferon-induced protein 44-like
ITPKA inositol-trisphosphate 3-kinase A
KIAA1107 KIAA1107
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LNPEP leucyl/cystinyl aminopeptidase
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
LYRM9 LYR motif containing 9
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MED9 mediator complex subunit 9
MLYCD malonyl-CoA decarboxylase
MT1M metallothionein 1M
MX1 MX dynamin-like GTPase 1
NDP Norrie disease (pseudoglioma)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPR3 natriuretic peptide receptor 3
NTSR1 neurotensin receptor 1 (high affinity)
OVGP1 oviductal glycoprotein 1, 120kDa
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLD2 phospholipase D2
POMT2 protein-O-mannosyltransferase 2
PPCS phosphopantothenoylcysteine synthetase
PRAME preferentially expressed antigen in melanoma
PRR15L proline rich 15-like
RNF126P1 ring finger protein 126 pseudogene 1
RPH3AL rabphilin 3A-like (without C2 domains)
SLC12A8 solute carrier family 12, member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLITRK5 SLIT and NTRK-like family, member 5
SOX9 SRY (sex determining region Y)-box 9
SPIDR scaffolding protein involved in DNA repair
STK16 serine/threonine kinase 16
STON1 stonin 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TENM4 teneurin transmembrane protein 4
TMEM53 transmembrane protein 53
TMSB15A thymosin beta 15a
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPAN1 tetraspanin 1
TUBA3C tubulin, alpha 3c
WNT10B wingless-type MMTV integration site family, member 10B
XK X-linked Kx blood group
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZFP30 ZFP30 zinc finger protein
ZNF205 zinc finger protein 205
ZNF34 zinc finger protein 34
ZNF862 zinc finger protein 862
ZSCAN5A zinc finger and SCAN domain containing 5A