cerebral ischemia Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002637
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Genes

175 genes associated with the cerebral ischemia phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
TRIM65 tripartite motif containing 65 1.72215
TRIM47 tripartite motif containing 47 1.47083
WBP2 WW domain binding protein 2 1.26698
PDCD11 programmed cell death 11 1.07635
FBF1 Fas (TNFRSF6) binding factor 1 0.974864
MRPL38 mitochondrial ribosomal protein L38 0.93785
NT5C2 5'-nucleotidase, cytosolic II 0.923916
PMF1 polyamine-modulated factor 1 0.919744
UNC13D unc-13 homolog D (C. elegans) 0.915706
COL25A1 collagen, type XXV, alpha 1 0.899912
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.860376
PTGDR prostaglandin D2 receptor (DP) 0.844241
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.834343
AMZ2P1 archaelysin family metallopeptidase 2 pseudogene 1 0.809986
CALHM1 calcium homeostasis modulator 1 0.809986
PRDM16 PR domain containing 16 0.790435
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.790435
PPP1R36 protein phosphatase 1, regulatory subunit 36 0.752335
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.747666
CHL1 cell adhesion molecule L1-like 0.743226
SETBP1 SET binding protein 1 0.734535
LEPROTL1 leptin receptor overlapping transcript-like 1 0.734535
FOXP2 forkhead box P2 0.730213
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.722116
CNTNAP2 contactin associated protein-like 2 0.707523
PITRM1 pitrilysin metallopeptidase 1 0.707523
IGSF21 immunoglobin superfamily, member 21 0.687523
KIRREL3 kin of IRRE like 3 (Drosophila) 0.681679
LOC285692 uncharacterized LOC285692 0.681679
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.675718
GEMIN6 gem (nuclear organelle) associated protein 6 0.669923
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.669923
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.664442
SLC25A44 solute carrier family 25, member 44 0.656743
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.656743
ICA1L islet cell autoantigen 1,69kDa-like 0.644641
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.642222
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.635284
NCOA2 nuclear receptor coactivator 2 0.633071
GMDS GDP-mannose 4,6-dehydratase 0.628781
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.622665
CALCRL calcitonin receptor-like 0.622665
FHOD3 formin homology 2 domain containing 3 0.614969
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.611229
PCGF6 polycomb group ring finger 6 0.604135
MYO6 myosin VI 0.599122
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.597506
COLGALT2 collagen beta(1-O)galactosyltransferase 2 0.589794
SH3PXD2A SH3 and PX domains 2A 0.588321
SRSF7 serine/arginine-rich splicing factor 7 0.58687
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.58687
CARF calcium responsive transcription factor 0.58687
AK9 adenylate kinase 9 0.580678
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.57836
GALM galactose mutarotase (aldose 1-epimerase) 0.577224
WASF3 WAS protein family, member 3 0.576102
RHBDD1 rhomboid domain containing 1 0.573902
ZFHX3 zinc finger homeobox 3 0.542759
FMNL2 formin-like 2 0.490125
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 0.463959
PAPPA2 pappalysin 2 0.451464
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.451464
PHF20L1 PHD finger protein 20-like 1 0.444568
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.44005
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 0.437499
ABHD2 abhydrolase domain containing 2 0.433116
UBE2Z ubiquitin-conjugating enzyme E2Z 0.433035
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.424122
PTPRD protein tyrosine phosphatase, receptor type, D 0.419638
TG thyroglobulin 0.419346
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 0.418777
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 0.417822
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3 0.416666
C1ORF177 chromosome 1 open reading frame 177 0.414929
A2ML1 alpha-2-macroglobulin-like 1 0.41339
PDGFRL platelet-derived growth factor receptor-like 0.413288
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.412794
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.411963
CELA2A chymotrypsin-like elastase family, member 2A 0.410331
TRAPPC11 trafficking protein particle complex 11 0.410331
SPATA5 spermatogenesis associated 5 0.410208
DLG2 discs, large homolog 2 (Drosophila) 0.409874
RYR2 ryanodine receptor 2 (cardiac) 0.409622
CDH13 cadherin 13 0.40839
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.407939
NCAM1 neural cell adhesion molecule 1 0.407287
TMEM181 transmembrane protein 181 0.406944
TMPRSS15 transmembrane protease, serine 15 0.406809
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.406221
DOCK4 dedicator of cytokinesis 4 0.406032
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.405641
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.405515
PTPRT protein tyrosine phosphatase, receptor type, T 0.404401
ADCY8 adenylate cyclase 8 (brain) 0.404379
FNDC3B fibronectin type III domain containing 3B 0.404155
LUZP2 leucine zipper protein 2 0.403217
TNR tenascin R 0.403217
TMEM71 transmembrane protein 71 0.403159
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.403054
UMODL1 uromodulin-like 1 0.402978
CCDC3 coiled-coil domain containing 3 0.402885
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.402866
PRMT8 protein arginine methyltransferase 8 0.402612
TPTE2P1 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 0.402514
ADAM17 ADAM metallopeptidase domain 17 0.40247
KIAA0020 KIAA0020 0.402383
ZNF366 zinc finger protein 366 0.402365
SGK1 serum/glucocorticoid regulated kinase 1 0.402331
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 0.402093
BTLA B and T lymphocyte associated 0.401823
NIN ninein (GSK3B interacting protein) 0.401593
ANO3 anoctamin 3 0.401593
LINC00474 long intergenic non-protein coding RNA 474 0.401436
NLRP9 NLR family, pyrin domain containing 9 0.400021
RGS13 regulator of G-protein signaling 13 0.399886
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.399059
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A 0.397475
PPT2 palmitoyl-protein thioesterase 2 0.396875
DGCR2 DiGeorge syndrome critical region gene 2 0.396514
PZP pregnancy-zone protein 0.395833
MCC mutated in colorectal cancers 0.395693
HHAT hedgehog acyltransferase 0.394942
ANO6 anoctamin 6 0.394569
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.393829
OTOG otogelin 0.393559
GLIS1 GLIS family zinc finger 1 0.391648
BCL2L2 BCL2-like 2 0.391468
CSMD3 CUB and Sushi multiple domains 3 0.390842
UBA2 ubiquitin-like modifier activating enzyme 2 0.390445
SULF1 sulfatase 1 0.390125
RBM20 RNA binding motif protein 20 0.389938
BCAN brevican 0.389633
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.388361
GRID1 glutamate receptor, ionotropic, delta 1 0.386738
ARHGAP44 Rho GTPase activating protein 44 0.38641
HEPACAM2 HEPACAM family member 2 0.38633
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.38617
UBA6 ubiquitin-like modifier activating enzyme 6 0.384917
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.384518
GRM7 glutamate receptor, metabotropic 7 0.384358
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.383187
STK32B serine/threonine kinase 32B 0.383167
IRF8 interferon regulatory factor 8 0.382861
THRB thyroid hormone receptor, beta 0.382642
TMEM165 transmembrane protein 165 0.382105
PIGR polymeric immunoglobulin receptor 0.381586
MBL2 mannose-binding lectin (protein C) 2, soluble 0.381219
PRR5L proline rich 5 like 0.381011
SOX5 SRY (sex determining region Y)-box 5 0.380899
CHSY3 chondroitin sulfate synthase 3 0.380825
C10ORF35 chromosome 10 open reading frame 35 0.380461
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.380124
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.380037
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.379882
PKNOX1 PBX/knotted 1 homeobox 1 0.379813
CCDC132 coiled-coil domain containing 132 0.379559
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.379526
JAKMIP2 janus kinase and microtubule interacting protein 2 0.379245
HUNK hormonally up-regulated Neu-associated kinase 0.379066
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.378795
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.378089
SPEG SPEG complex locus 0.378089
CETP cholesteryl ester transfer protein, plasma 0.377662
ARHGAP6 Rho GTPase activating protein 6 0.377648
DRD2 dopamine receptor D2 0.377292
ARHGAP24 Rho GTPase activating protein 24 0.377096
ADGRB3 adhesion G protein-coupled receptor B3 0.377069
BFSP1 beaded filament structural protein 1, filensin 0.376581
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.376528
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 0.372347
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.358325
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.356215
KCNK17 potassium channel, two pore domain subfamily K, member 17 0.350747
SPTB spectrin, beta, erythrocytic 0.350747
KCNIP4 Kv channel interacting protein 4 0.350525