centriole Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle. (Gene Ontology, GO_0005814)
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Genes

263 proteins co-occuring with the centriole cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PLK4 polo-like kinase 4 2.47687
CEP152 centrosomal protein 152kDa 2.06267
CNTLN centlein, centrosomal protein 2.02927
CENPJ centromere protein J 1.96145
CEP135 centrosomal protein 135kDa 1.93483
PCNT pericentrin 1.85868
CEP164 centrosomal protein 164kDa 1.74574
ODF2 outer dense fiber of sperm tails 2 1.65874
CEP192 centrosomal protein 192kDa 1.61002
NIN ninein (GSK3B interacting protein) 1.59604
STIL SCL/TAL1 interrupting locus 1.56617
CNTROB centrobin, centrosomal BRCA2 interacting protein 1.49097
CEP97 centrosomal protein 97kDa 1.46665
PLK1 polo-like kinase 1 1.44742
CEP250 centrosomal protein 250kDa 1.4288
CETN2 centrin, EF-hand protein, 2 1.41138
NEK2 NIMA-related kinase 2 1.37741
TUBE1 tubulin, epsilon 1 1.34338
CEP63 centrosomal protein 63kDa 1.31735
CEP170 centrosomal protein 170kDa 1.26181
CEP120 centrosomal protein 120kDa 1.25601
POC1B POC1 centriolar protein B 1.2476
TTBK2 tau tubulin kinase 2 1.23505
SASS6 spindle assembly 6 homolog (C. elegans) 1.19263
CEP290 centrosomal protein 290kDa 1.17055
C2CD3 C2 calcium-dependent domain containing 3 1.16953
OFD1 oral-facial-digital syndrome 1 1.16799
CEP89 centrosomal protein 89kDa 1.13318
CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.11837
IFT88 intraflagellar transport 88 1.08628
CETN3 centrin, EF-hand protein, 3 1.08425
TUBA1A tubulin, alpha 1a 1.06549
CETN1 centrin, EF-hand protein, 1 1.06144
SCLT1 sodium channel and clathrin linker 1 1.05942
POC1A POC1 centriolar protein A 1.04934
FOXJ1 forkhead box J1 1.04532
PLK2 polo-like kinase 2 1.0403
CEP295 centrosomal protein 295kDa 1.03779
CEP83 centrosomal protein 83kDa 1.03029
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 1.0243
KIF24 kinesin family member 24 1.00843
FAM161A family with sequence similarity 161, member A 0.995142
CCDC78 coiled-coil domain containing 78 0.991714
CEP57 centrosomal protein 57kDa 0.987317
TUBD1 tubulin, delta 1 0.978559
CDK2 cyclin-dependent kinase 2 0.978074
CEP70 centrosomal protein 70kDa 0.976135
POC5 POC5 centriolar protein 0.964549
NEK1 NIMA-related kinase 1 0.960707
RTTN rotatin 0.949236
NEURL4 neuralized E3 ubiquitin protein ligase 4 0.921386
TSSK2 testis-specific serine kinase 2 0.868126
NEK8 NIMA-related kinase 8 0.856635
CCNF cyclin F 0.854339
TSKS testis-specific serine kinase substrate 0.850665
FBXW5 F-box and WD repeat domain containing 5 0.843778
CCP110 centriolar coiled coil protein 110kDa 0.840105
LRRC45 leucine rich repeat containing 45 0.831384
TBCCD1 TBCC domain containing 1 0.825877
HAUS2 HAUS augmin-like complex, subunit 2 0.809817
CEP350 centrosomal protein 350kDa 0.809817
NPHP4 nephronophthisis 4 0.802021
NUBP1 nucleotide binding protein 1 0.801104
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.783241
C10ORF90 chromosome 10 open reading frame 90 0.781869
NUBP2 nucleotide binding protein 2 0.779126
SPICE1 spindle and centriole associated protein 1 0.768627
WDR34 WD repeat domain 34 0.764982
KIAA0586 KIAA0586 0.758161
NUMA1 nuclear mitotic apparatus protein 1 0.755891
CCDC14 coiled-coil domain containing 14 0.75181
KIAA0753 KIAA0753 0.75181
CCDC13 coiled-coil domain containing 13 0.749094
KIZ kizuna centrosomal protein 0.745929
RAB8A RAB8A, member RAS oncogene family 0.741416
SGOL1 shugoshin-like 1 (S. pombe) 0.735115
SDCCAG8 serologically defined colon cancer antigen 8 0.725258
INVS inversin 0.723472
USP33 ubiquitin specific peptidase 33 0.715458
MKS1 Meckel syndrome, type 1 0.711465
KCTD17 potassium channel tetramerization domain containing 17 0.707924
CCDC67 coiled-coil domain containing 67 0.695587
AHI1 Abelson helper integration site 1 0.688139
FBF1 Fas (TNFRSF6) binding factor 1 0.676368
CEP76 centrosomal protein 76kDa 0.671593
SPEF1 sperm flagellar 1 0.669858
SHH sonic hedgehog 0.665529
DCTN1 dynactin 1 0.65905
PARD6G par-6 family cell polarity regulator gamma 0.658619
MPEG1 macrophage expressed 1 0.646574
IFT20 intraflagellar transport 20 0.641429
ARL13B ADP-ribosylation factor-like 13B 0.638005
GLOD4 glyoxalase domain containing 4 0.633305
ZMYND10 zinc finger, MYND-type containing 10 0.615437
SPATC1 spermatogenesis and centriole associated 1 0.614165
TBCD tubulin folding cofactor D 0.613318
CDK1 cyclin-dependent kinase 1 0.609086
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.603596
TPGS1 tubulin polyglutamylase complex subunit 1 0.592232
CC2D2A coiled-coil and C2 domain containing 2A 0.589714
BBS2 Bardet-Biedl syndrome 2 0.585523
NEK7 NIMA-related kinase 7 0.582594
NPHP3 nephronophthisis 3 (adolescent) 0.580504
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 0.578416
NPHP1 nephronophthisis 1 (juvenile) 0.576747
BRCA1 breast cancer 1, early onset 0.570913
RILPL1 Rab interacting lysosomal protein-like 1 0.565923
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.549773
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.548122
KIF11 kinesin family member 11 0.544823
TMEM67 transmembrane protein 67 0.544411
TUBGCP2 tubulin, gamma complex associated protein 2 0.543587
PTTG1 pituitary tumor-transforming 1 0.543176
PCM1 pericentriolar material 1 0.535361
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.527569
SPATA4 spermatogenesis associated 4 0.526341
IFT52 intraflagellar transport 52 0.520206
STOML3 stomatin (EPB72)-like 3 0.519389
MOB1B MOB kinase activator 1B 0.518165
ABLIM3 actin binding LIM protein family, member 3 0.515716
MEIG1 meiosis/spermiogenesis associated 1 0.51164
CBY1 chibby homolog 1 (Drosophila) 0.510418
KIF3A kinesin family member 3A 0.509197
TEKT3 tektin 3 0.507977
RPGR retinitis pigmentosa GTPase regulator 0.503912
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.500664
MDM1 Mdm1 nuclear protein homolog (mouse) 0.500664
CEP55 centrosomal protein 55kDa 0.499447
TSSK6 testis-specific serine kinase 6 0.499042
USP9X ubiquitin specific peptidase 9, X-linked 0.49742
NEK6 NIMA-related kinase 6 0.493371
ARL3 ADP-ribosylation factor-like 3 0.492561
E2F5 E2F transcription factor 5, p130-binding 0.491348
FAM161B family with sequence similarity 161, member B 0.489731
NEK9 NIMA-related kinase 9 0.482467
SPAG5 sperm associated antigen 5 0.482467
CEP162 centrosomal protein 162kDa 0.478038
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.472412
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.462798
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.452427
CCNY cyclin Y 0.438937
HOOK2 hook microtubule-tethering protein 2 0.43696
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.43696
GLI3 GLI family zinc finger 3 0.435775
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 0.43538
CUL1 cullin 1 0.431041
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.430253
TEKT4 tektin 4 0.429465
RILPL2 Rab interacting lysosomal protein-like 2 0.428284
MOB1A MOB kinase activator 1A 0.426318
AGTPBP1 ATP/GTP binding protein 1 0.425924
AGBL4 ATP/GTP binding protein-like 4 0.424353
KATNB1 katanin p80 (WD repeat containing) subunit B 1 0.422389
PKD1L1 polycystic kidney disease 1 like 1 0.421604
CCNO cyclin O 0.418077
ABLIM1 actin binding LIM protein 1 0.413382
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 0.407919
AURKC aurora kinase C 0.40675
TBCC tubulin folding cofactor C 0.403637
GLI2 GLI family zinc finger 2 0.401693
DNALI1 dynein, axonemal, light intermediate chain 1 0.399751
LRRC6 leucine rich repeat containing 6 0.399363
GOLGB1 golgin B1 0.397811
USP44 ubiquitin specific peptidase 44 0.397811
TROAP trophinin associated protein 0.396648
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.395485
TEKT1 tektin 1 0.392001
BBS4 Bardet-Biedl syndrome 4 0.381584
RANBP10 RAN binding protein 10 0.376586
LZTS2 leucine zipper, putative tumor suppressor 2 0.372366
LCA5 Leber congenital amaurosis 5 0.370833
VDAC3 voltage-dependent anion channel 3 0.37045
SPAG16 sperm associated antigen 16 0.368153
IFT74 intraflagellar transport 74 0.367388
TP53 tumor protein p53 0.365859
CNN2 calponin 2 0.364713
HSPB11 heat shock protein family B (small), member 11 0.363185
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.357467
CEP131 centrosomal protein 131kDa 0.355944
SSTR3 somatostatin receptor 3 0.349105
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.348725
AURKA aurora kinase A 0.347967
SKP1 S-phase kinase-associated protein 1 0.342664
TEKT2 tektin 2 (testicular) 0.327581
FBXO5 F-box protein 5 0.325327
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.312971
PARP3 poly (ADP-ribose) polymerase family, member 3 0.312224
BBS5 Bardet-Biedl syndrome 5 0.309986
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.305888
CDC25B cell division cycle 25B 0.30254
BNC1 basonuclin 1 0.302168
SPAG4 sperm associated antigen 4 0.301425
STK38 serine/threonine kinase 38 0.294748
ACPP acid phosphatase, prostate 0.291787
BBS7 Bardet-Biedl syndrome 7 0.291787
ZBTB20 zinc finger and BTB domain containing 20 0.289569
PACRG PARK2 co-regulated 0.285138
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.282926
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.282926
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.282558
EVI5 ecotropic viral integration site 5 0.281821
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.276304
NUP62 nucleoporin 62kDa 0.274835
IFT46 intraflagellar transport 46 0.274468
AKAP4 A kinase (PRKA) anchor protein 4 0.273734
ALMS1 Alstrom syndrome protein 1 0.272267
UNC119 unc-119 homolog (C. elegans) 0.272267
CENPW centromere protein W 0.270434
PARK2 parkin RBR E3 ubiquitin protein ligase 0.270068
CENPE centromere protein E, 312kDa 0.268237
MLF1 myeloid leukemia factor 1 0.263485
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.263485
CC2D1A coiled-coil and C2 domain containing 1A 0.259837
CDC20 cell division cycle 20 0.259837
AKAP3 A kinase (PRKA) anchor protein 3 0.258016
WDR19 WD repeat domain 19 0.25547
SCYL1 SCY1-like 1 (S. cerevisiae) 0.254743
SIK2 salt-inducible kinase 2 0.251114
E2F4 E2F transcription factor 4, p107/p130-binding 0.24713
MRPL49 mitochondrial ribosomal protein L49 0.246046
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.241356
MAP4 microtubule-associated protein 4 0.238478
SGOL2 shugoshin-like 2 (S. pombe) 0.238478
MKKS McKusick-Kaufman syndrome 0.237042
SAV1 salvador family WW domain containing protein 1 0.236324
SKA1 spindle and kinetochore associated complex subunit 1 0.234533
FRMD6 FERM domain containing 6 0.232386
CRYGD crystallin, gamma D 0.230958
ERAS ES cell expressed Ras 0.228464
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.225976
TUBGCP4 tubulin, gamma complex associated protein 4 0.22279
FTCD formimidoyltransferase cyclodeaminase 0.220321
MARK4 MAP/microtubule affinity-regulating kinase 4 0.215063
CCNG2 cyclin G2 0.214714
NXN nucleoredoxin 0.212974
CIB1 calcium and integrin binding 1 (calmyrin) 0.211587
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.209169
TPX2 TPX2, microtubule-associated 0.208137
ARR3 arrestin 3, retinal (X-arrestin) 0.200328
MINK1 misshapen-like kinase 1 0.199325
NOTCH1 notch 1 0.196999
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.196999
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.194371
MAP2 microtubule-associated protein 2 0.192746
PKD2L1 polycystic kidney disease 2-like 1 0.192746
POLB polymerase (DNA directed), beta 0.192746
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.1921
CDK19 cyclin-dependent kinase 19 0.1921
ANAPC5 anaphase promoting complex subunit 5 0.188905
RGS14 regulator of G-protein signaling 14 0.188905
HYLS1 hydrolethalus syndrome 1 0.188274
WNT2B wingless-type MMTV integration site family, member 2B 0.183631
BRCA2 breast cancer 2, early onset 0.181823
DVL3 dishevelled segment polarity protein 3 0.181524
NDE1 nudE neurodevelopment protein 1 0.181227
STK3 serine/threonine kinase 3 0.180634
TTK TTK protein kinase 0.178877
TSPO translocator protein (18kDa) 0.178011
SNED1 sushi, nidogen and EGF-like domains 1 0.173814
CCNB1 cyclin B1 0.17141
PNP purine nucleoside phosphorylase 0.169604
GMNN geminin, DNA replication inhibitor 0.1632
STK26 serine/threonine protein kinase 26 0.160456