cellular transition metal ion homeostasis Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. (Gene Ontology, GO_0046916)
External Link http://amigo.geneontology.org/amigo/term/GO:0046916
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Genes

89 genes participating in the cellular transition metal ion homeostasis biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACO1 aconitase 1, soluble
ALAS2 5'-aminolevulinate synthase 2
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
ARF1 ADP-ribosylation factor 1
ATOX1 antioxidant 1 copper chaperone
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP6V1G3 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
BMP6 bone morphogenetic protein 6
CCDC22 coiled-coil domain containing 22
CP ceruloplasmin (ferroxidase)
CYBRD1 cytochrome b reductase 1
FAM132B family with sequence similarity 132, member B
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FTH1 ferritin, heavy polypeptide 1
FTHL17 ferritin, heavy polypeptide-like 17
FTL ferritin, light polypeptide
FTMT ferritin mitochondrial
FXN frataxin
GDF2 growth differentiation factor 2
HAMP hepcidin antimicrobial peptide
HEPH hephaestin
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HPX hemopexin
IREB2 iron-responsive element binding protein 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LTF lactotransferrin
MCOLN1 mucolipin 1
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MT1X metallothionein 1X
MT2A metallothionein 2A
MT3 metallothionein 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDFIP1 Nedd4 family interacting protein 1
NUBP1 nucleotide binding protein 1
PRNP prion protein
SCARA5 scavenger receptor class A, member 5
SCO1 SCO1 cytochrome c oxidase assembly protein
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC22A17 solute carrier family 22, member 17
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC46A1 solute carrier family 46 (folate transporter), member 1
SOD1 superoxide dismutase 1, soluble
STEAP3 STEAP family member 3, metalloreductase
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TF transferrin
TFR2 transferrin receptor 2
TFRC transferrin receptor