cellular senescence Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest. (Gene Ontology, GO_0090398)
External Link http://amigo.geneontology.org/amigo/term/GO:0090398
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Genes

28 genes participating in the cellular senescence biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ARNTL aryl hydrocarbon receptor nuclear translocator-like
C2ORF40 chromosome 2 open reading frame 40
CALR calreticulin
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HRAS Harvey rat sarcoma viral oncogene homolog
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KAT6A K(lysine) acetyltransferase 6A
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
OPA1 optic atrophy 1 (autosomal dominant)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PML promyelocytic leukemia
PRKCD protein kinase C, delta
SIRT1 sirtuin 1
SMC5 structural maintenance of chromosomes 5
SMC6 structural maintenance of chromosomes 6
SRF serum response factor (c-fos serum response element-binding transcription factor)
TBX2 T-box 2
TBX3 T-box 3
TERF2 telomeric repeat binding factor 2
TP53 tumor protein p53
ULK3 unc-51 like kinase 3
WNT16 wingless-type MMTV integration site family, member 16