cell junction Gene Set

Dataset COMPARTMENTS Experimental Protein Localization Evidence Scores
Category proteomics
Type cellular component
Description A cellular component that forms a specialized region of connection between two cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. (Gene Ontology, GO_0030054)
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Genes

246 proteins localized to the cell junction cellular component in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TRPC7 transient receptor potential cation channel, subfamily C, member 7 1.02676
TJP1 tight junction protein 1 1.02676
CGN cingulin 1.02676
FHL2 four and a half LIM domains 2 1.02676
PXN paxillin 1.02676
PDLIM7 PDZ and LIM domain 7 (enigma) 1.02676
ENAH enabled homolog (Drosophila) 1.02676
PDLIM5 PDZ and LIM domain 5 0.233497
PNMA1 paraneoplastic Ma antigen 1 0.233497
ZCCHC6 zinc finger, CCHC domain containing 6 0.233497
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.233497
LIMA1 LIM domain and actin binding 1 0.233497
MYBPC1 myosin binding protein C, slow type 0.233497
EBAG9 estrogen receptor binding site associated, antigen, 9 0.233497
PEAR1 platelet endothelial aggregation receptor 1 0.233497
MICALL1 MICAL-like 1 0.233497
LASP1 LIM and SH3 protein 1 0.233497
TNK1 tyrosine kinase, non-receptor, 1 0.233497
ZDHHC5 zinc finger, DHHC-type containing 5 0.233497
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.233497
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.233497
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.233497
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 0.233497
COBL cordon-bleu WH2 repeat protein 0.233497
N4BP2 NEDD4 binding protein 2 0.233497
PRICKLE1 prickle homolog 1 (Drosophila) 0.233497
HOMER2 homer scaffolding protein 2 0.233497
CRB3 crumbs family member 3 0.233497
OSBP oxysterol binding protein 0.233497
ELMO3 engulfment and cell motility 3 0.233497
PKP2 plakophilin 2 0.233497
PKP3 plakophilin 3 0.233497
CABLES2 Cdk5 and Abl enzyme substrate 2 0.233497
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.233497
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.233497
RPUSD1 RNA pseudouridylate synthase domain containing 1 0.233497
TDRKH tudor and KH domain containing 0.233497
TJP2 tight junction protein 2 0.233497
RAB25 RAB25, member RAS oncogene family 0.233497
RAB23 RAB23, member RAS oncogene family 0.233497
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 0.233497
RTN4R reticulon 4 receptor 0.233497
KIF22 kinesin family member 22 0.233497
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.233497
SPERT spermatid associated 0.233497
MISP mitotic spindle positioning 0.233497
SENP1 SUMO1/sentrin specific peptidase 1 0.233497
HENMT1 HEN1 methyltransferase homolog 1 (Arabidopsis) 0.233497
FBLN7 fibulin 7 0.233497
TES testin LIM domain protein 0.233497
DSG2 desmoglein 2 0.233497
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.233497
SIKE1 suppressor of IKBKE 1 0.233497
MEF2B myocyte enhancer factor 2B 0.233497
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.233497
TNC tenascin C 0.233497
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.233497
SLC23A3 solute carrier family 23, member 3 0.233497
ZNF236 zinc finger protein 236 0.233497
MOAP1 modulator of apoptosis 1 0.233497
ZNF185 zinc finger protein 185 (LIM domain) 0.233497
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.233497
PLEC plectin 0.233497
MYO5A myosin VA (heavy chain 12, myoxin) 0.233497
C11ORF73 chromosome 11 open reading frame 73 0.233497
OCLN occludin 0.233497
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.233497
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.233497
AATF apoptosis antagonizing transcription factor 0.233497
CCDC66 coiled-coil domain containing 66 0.233497
HSH2D hematopoietic SH2 domain containing 0.233497
IQGAP1 IQ motif containing GTPase activating protein 1 0.233497
SMC5 structural maintenance of chromosomes 5 0.233497
MYO18A myosin XVIIIA 0.233497
ZNF688 zinc finger protein 688 0.233497
FAM73B family with sequence similarity 73, member B 0.233497
ZYX zyxin 0.233497
FCMR Fc fragment of IgM receptor 0.233497
SHROOM2 shroom family member 2 0.233497
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.233497
PARVA parvin, alpha 0.233497
IGFLR1 IGF-like family receptor 1 0.233497
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 0.233497
GK5 glycerol kinase 5 (putative) 0.233497
CADM1 cell adhesion molecule 1 0.233497
MYH9 myosin, heavy chain 9, non-muscle 0.233497
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.233497
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.233497
F11R F11 receptor 0.233497
TRIM38 tripartite motif containing 38 0.233497
USP40 ubiquitin specific peptidase 40 0.233497
VASP vasodilator-stimulated phosphoprotein 0.233497
NLK nemo-like kinase 0.233497
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.233497
MTFR1L mitochondrial fission regulator 1-like 0.233497
CHRD chordin 0.233497
CLDN2 claudin 2 0.233497
REXO2 RNA exonuclease 2 0.233497
C1ORF86 chromosome 1 open reading frame 86 0.233497
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.233497
RAET1E retinoic acid early transcript 1E 0.233497
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.233497
PCLO piccolo presynaptic cytomatrix protein 0.233497
FAM136A family with sequence similarity 136, member A 0.233497
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 0.233497
BCAR1 breast cancer anti-estrogen resistance 1 0.233497
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.233497
ZNF16 zinc finger protein 16 0.233497
CLIP4 CAP-GLY domain containing linker protein family, member 4 0.233497
HOXC5 homeobox C5 0.233497
RASAL2 RAS protein activator like 2 0.233497
RASAL1 RAS protein activator like 1 (GAP1 like) 0.233497
PRR15 proline rich 15 0.233497
TRMT6 tRNA methyltransferase 6 0.233497
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase 0.233497
NAV1 neuron navigator 1 0.233497
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.233497
PLEKHA6 pleckstrin homology domain containing, family A member 6 0.233497
BRSK1 BR serine/threonine kinase 1 0.233497
SNRK SNF related kinase 0.233497
ILK integrin-linked kinase 0.233497
GPATCH1 G patch domain containing 1 0.233497
ING5 inhibitor of growth family, member 5 0.233497
GCLM glutamate-cysteine ligase, modifier subunit 0.233497
CMTR2 cap methyltransferase 2 0.233497
RFC1 replication factor C (activator 1) 1, 145kDa 0.233497
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.233497
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.233497
DCTN6 dynactin 6 0.233497
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.233497
PVRL3 poliovirus receptor-related 3 0.233497
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 0.233497
ARL2 ADP-ribosylation factor-like 2 0.233497
SMIM11 small integral membrane protein 11 0.233497
LRRC7 leucine rich repeat containing 7 0.233497
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.233497
BASP1 brain abundant, membrane attached signal protein 1 0.233497
STRAP serine/threonine kinase receptor associated protein 0.233497
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 0.233497
ZNF276 zinc finger protein 276 0.233497
CTXN1 cortexin 1 0.233497
RSC1A1 regulatory solute carrier protein, family 1, member 1 0.233497
PARD3 par-3 family cell polarity regulator 0.233497
SNX32 sorting nexin 32 0.233497
C2CD4B C2 calcium-dependent domain containing 4B 0.233497
DSC3 desmocollin 3 0.233497
TEKT2 tektin 2 (testicular) 0.233497
NRIP1 nuclear receptor interacting protein 1 0.233497
DSP desmoplakin 0.233497
CNTD1 cyclin N-terminal domain containing 1 0.233497
ZFP90 ZFP90 zinc finger protein 0.233497
CXADR coxsackie virus and adenovirus receptor 0.233497
COPS4 COP9 signalosome subunit 4 0.233497
LRP2 low density lipoprotein receptor-related protein 2 0.233497
FERMT2 fermitin family member 2 0.233497
ACOT13 acyl-CoA thioesterase 13 0.233497
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.233497
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 0.233497
ACSS3 acyl-CoA synthetase short-chain family member 3 0.233497
MAP1S microtubule-associated protein 1S 0.233497
SORBS3 sorbin and SH3 domain containing 3 0.233497
SORBS1 sorbin and SH3 domain containing 1 0.233497
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.233497
GPATCH2 G patch domain containing 2 0.233497
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.233497
TMEM164 transmembrane protein 164 0.233497
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.233497
ERGIC3 ERGIC and golgi 3 0.233497
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.233497
ABI1 abl-interactor 1 0.233497
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.233497
FCHSD2 FCH and double SH3 domains 2 0.233497
UBXN10 UBX domain protein 10 0.233497
SLC38A6 solute carrier family 38, member 6 0.233497
PLCD3 phospholipase C, delta 3 0.233497
IFI30 interferon, gamma-inducible protein 30 0.233497
C8ORF37 chromosome 8 open reading frame 37 0.233497
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.233497
EFCAB11 EF-hand calcium binding domain 11 0.233497
TPD52L1 tumor protein D52-like 1 0.233497
TMEM251 transmembrane protein 251 0.233497
GPR157 G protein-coupled receptor 157 0.233497
EXD3 exonuclease 3'-5' domain containing 3 0.233497
MEIS1 Meis homeobox 1 0.233497
ITGAV integrin, alpha V 0.233497
ERCC4 excision repair cross-complementation group 4 0.233497
CHD2 chromodomain helicase DNA binding protein 2 0.233497
STAG1 stromal antigen 1 0.233497
NUMB numb homolog (Drosophila) 0.233497
LPP LIM domain containing preferred translocation partner in lipoma 0.233497
LMCD1 LIM and cysteine-rich domains 1 0.233497
DCAF13 DDB1 and CUL4 associated factor 13 0.233497
TAS2R42 taste receptor, type 2, member 42 0.233497
FAF1 Fas (TNFRSF6) associated factor 1 0.233497
UBOX5 U-box domain containing 5 0.233497
NCAM1 neural cell adhesion molecule 1 0.233497
SMAGP small cell adhesion glycoprotein 0.233497
CERCAM cerebral endothelial cell adhesion molecule 0.233497
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.233497
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.233497
IQSEC1 IQ motif and Sec7 domain 1 0.233497
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.233497
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 0.233497
MYO1B myosin IB 0.233497
GID8 GID complex subunit 8 0.233497
SPN sialophorin 0.233497
CORO2B coronin, actin binding protein, 2B 0.233497
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 0.233497
FIBCD1 fibrinogen C domain containing 1 0.233497
ANKRD45 ankyrin repeat domain 45 0.233497
SDC1 syndecan 1 0.233497
TLN1 talin 1 0.233497
TLN2 talin 2 0.233497
SHKBP1 SH3KBP1 binding protein 1 0.233497
C16ORF59 chromosome 16 open reading frame 59 0.233497
CARD6 caspase recruitment domain family, member 6 0.233497
EXOSC7 exosome component 7 0.233497
GLRX3 glutaredoxin 3 0.233497
AQP4 aquaporin 4 0.233497
LAPTM4B lysosomal protein transmembrane 4 beta 0.233497
FAM222A family with sequence similarity 222, member A 0.233497
PGS1 phosphatidylglycerophosphate synthase 1 0.233497
NUP214 nucleoporin 214kDa 0.233497
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18 0.233497
AMOTL1 angiomotin like 1 0.233497
MRPS18C mitochondrial ribosomal protein S18C 0.233497
TMEM205 transmembrane protein 205 0.233497
C9ORF172 chromosome 9 open reading frame 172 0.233497
AGGF1 angiogenic factor with G patch and FHA domains 1 0.233497
TADA1 transcriptional adaptor 1 0.233497
NMT1 N-myristoyltransferase 1 0.233497
AHDC1 AT hook, DNA binding motif, containing 1 0.233497
KIAA1462 KIAA1462 0.233497
DHRS7B dehydrogenase/reductase (SDR family) member 7B 0.233497
TMEM53 transmembrane protein 53 0.233497
LIG4 ligase IV, DNA, ATP-dependent 0.233497
FRS2 fibroblast growth factor receptor substrate 2 0.233497
MEPCE methylphosphate capping enzyme 0.233497
TRIP6 thyroid hormone receptor interactor 6 0.233497
MRPL44 mitochondrial ribosomal protein L44 0.233497
WBSCR27 Williams Beuren syndrome chromosome region 27 0.233497
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 0.233497
CTNNBIP1 catenin, beta interacting protein 1 0.233497
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.233497
ARHGAP28 Rho GTPase activating protein 28 0.233497
HRASLS HRAS-like suppressor 0.233497