cefuroxime-6261 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cefuroxime-6261 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADGRG2 adhesion G protein-coupled receptor G2
AHI1 Abelson helper integration site 1
AIM1L absent in melanoma 1-like
APP amyloid beta (A4) precursor protein
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARSB arylsulfatase B
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
BPGM 2,3-bisphosphoglycerate mutase
C11ORF1 chromosome 11 open reading frame 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMKMT calmodulin-lysine N-methyltransferase
CD34 CD34 molecule
CDK6 cyclin-dependent kinase 6
CIR1 corepressor interacting with RBPJ, 1
COL5A1 collagen, type V, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CROCC ciliary rootlet coiled-coil, rootletin
CUL4B cullin 4B
DGAT1 diacylglycerol O-acyltransferase 1
DLC1 DLC1 Rho GTPase activating protein
DMTN dematin actin binding protein
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELSPBP1 epididymal sperm binding protein 1
ENO2 enolase 2 (gamma, neuronal)
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPOR erythropoietin receptor
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAS Fas cell surface death receptor
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GK glycerol kinase
GLG1 golgi glycoprotein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GSTP1 glutathione S-transferase pi 1
HOMER3 homer scaffolding protein 3
IL11 interleukin 11
IL27RA interleukin 27 receptor, alpha
IL5RA interleukin 5 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
ITPKB inositol-trisphosphate 3-kinase B
KIAA0355 KIAA0355
KIAA1107 KIAA1107
KLHL22 kelch-like family member 22
KRT17 keratin 17, type I
LPIN2 lipin 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MALT1 MALT1 paracaspase
MAP4 microtubule-associated protein 4
MAST4 microtubule associated serine/threonine kinase family member 4
MBNL2 muscleblind-like splicing regulator 2
MXD3 MAX dimerization protein 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEUROD4 neuronal differentiation 4
NOP14-AS1 NOP14 antisense RNA 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE8B phosphodiesterase 8B
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU2F2 POU class 2 homeobox 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRSS53 protease, serine, 53
RAB6B RAB6B, member RAS oncogene family
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RER1 retention in endoplasmic reticulum sorting receptor 1
REST RE1-silencing transcription factor
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF24 ring finger protein 24
SFXN3 sideroflexin 3
SH2D3A SH2 domain containing 3A
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLPI secretory leukocyte peptidase inhibitor
SMC4 structural maintenance of chromosomes 4
SMTN smoothelin
SP1 Sp1 transcription factor
SRPX sushi-repeat containing protein, X-linked
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIM1 stromal interaction molecule 1
TADA3 transcriptional adaptor 3
TBX5 T-box 5
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRBC1 T cell receptor beta constant 1
TSPAN9 tetraspanin 9
USP34 ubiquitin specific peptidase 34
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
WSB1 WD repeat and SOCS box containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF277 zinc finger protein 277
ZNF286A zinc finger protein 286A

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ACTL8 actin-like 8
AEN apoptosis enhancing nuclease
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGAP10 Rho GTPase activating protein 10
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB9 ankyrin repeat and SOCS box containing 9
BBS7 Bardet-Biedl syndrome 7
BMP15 bone morphogenetic protein 15
C10ORF88 chromosome 10 open reading frame 88
C17ORF85 chromosome 17 open reading frame 85
C2ORF44 chromosome 2 open reading frame 44
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CEP72 centrosomal protein 72kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNR2 cannabinoid receptor 2 (macrophage)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNM1 dynamin 1
DSCAM Down syndrome cell adhesion molecule
ECHDC2 enoyl CoA hydratase domain containing 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELOVL4 ELOVL fatty acid elongase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EVPL envoplakin
F8 coagulation factor VIII, procoagulant component
FPGS folylpolyglutamate synthase
FUZ fuzzy planar cell polarity protein
GAREM GRB2 associated, regulator of MAPK1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IGSF1 immunoglobulin superfamily, member 1
IL2 interleukin 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2 interferon regulatory factor 2
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
LNPEP leucyl/cystinyl aminopeptidase
LRP5 low density lipoprotein receptor-related protein 5
MITF microphthalmia-associated transcription factor
NKAIN1 Na+/K+ transporting ATPase interacting 1
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARPBP PARP1 binding protein
PDE12 phosphodiesterase 12
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMT2 protein-O-mannosyltransferase 2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PYCRL pyrroline-5-carboxylate reductase-like
PYGB phosphorylase, glycogen; brain
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RCOR3 REST corepressor 3
RECQL4 RecQ protein-like 4
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
RPL23AP7 ribosomal protein L23a pseudogene 7
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SH2B3 SH2B adaptor protein 3
SH2D4A SH2 domain containing 4A
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SND1-IT1 SND1 intronic transcript 1
SNHG3 small nucleolar RNA host gene 3
SOX3 SRY (sex determining region Y)-box 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STEAP3 STEAP family member 3, metalloreductase
STXBP2 syntaxin binding protein 2
TEAD3 TEA domain family member 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TUBGCP5 tubulin, gamma complex associated protein 5
TXLNG taxilin gamma
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBXN6 UBX domain protein 6
USP36 ubiquitin specific peptidase 36
WDR19 WD repeat domain 19
WLS wntless Wnt ligand secretion mediator
ZNF141 zinc finger protein 141
ZNF219 zinc finger protein 219
ZNF271P zinc finger protein 271, pseudogene
ZNF280D zinc finger protein 280D
ZNF442 zinc finger protein 442
ZNF623 zinc finger protein 623
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene