cefixime-4567 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the cefixime-4567 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
APOE apolipoprotein E
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMCX4 armadillo repeat containing, X-linked 4
C1ORF21 chromosome 1 open reading frame 21
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CELP carboxyl ester lipase pseudogene
CLEC11A C-type lectin domain family 11, member A
CNOT2 CCR4-NOT transcription complex, subunit 2
COL14A1 collagen, type XIV, alpha 1
CRYGC crystallin, gamma C
CYSLTR1 cysteinyl leukotriene receptor 1
DOCK5 dedicator of cytokinesis 5
DOK4 docking protein 4
EDN3 endothelin 3
ELN elastin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FAM189A1 family with sequence similarity 189, member A1
FGL1 fibrinogen-like 1
FRMD8 FERM domain containing 8
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAS7 growth arrest-specific 7
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPSM3 G-protein signaling modulator 3
GVINP1 GTPase, very large interferon inducible pseudogene 1
GYPB glycophorin B (MNS blood group)
GYPC glycophorin C (Gerbich blood group)
HHAT hedgehog acyltransferase
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXD11 homeobox D11
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IL1RL1 interleukin 1 receptor-like 1
IL2RA interleukin 2 receptor, alpha
IL32 interleukin 32
JAG1 jagged 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT19P2 keratin 19 pseudogene 2
KRT20 keratin 20, type I
KRT37 keratin 37, type I
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMNA lamin A/C
LOC100294391 uncharacterized LOC100294391
LRRTM2 leucine rich repeat transmembrane neuronal 2
LST1 leukocyte specific transcript 1
MBD2 methyl-CpG binding domain protein 2
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MSI1 musashi RNA-binding protein 1
MTSS1L metastasis suppressor 1-like
MYOZ3 myozenin 3
NELL2 NEL-like 2 (chicken)
NRP2 neuropilin 2
NUDC nudC nuclear distribution protein
PAOX polyamine oxidase (exo-N4-amino)
PCDHB17P protocadherin beta 17 pseudogene
PEX3 peroxisomal biogenesis factor 3
PHF20 PHD finger protein 20
PLBD1 phospholipase B domain containing 1
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRAMEF11 PRAME family member 11
PRDM14 PR domain containing 14
PTBP3 polypyrimidine tract binding protein 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB40C RAB40C, member RAS oncogene family
RBBP9 retinoblastoma binding protein 9
RGS10 regulator of G-protein signaling 10
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RTN1 reticulon 1
RUNX1 runt-related transcription factor 1
SC5D sterol-C5-desaturase
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC35F6 solute carrier family 35, member F6
SPAG8 sperm associated antigen 8
STAT2 signal transducer and activator of transcription 2, 113kDa
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAT tyrosine aminotransferase
TFEC transcription factor EC
TMEM212 transmembrane protein 212
TNNT3 troponin T type 3 (skeletal, fast)
TRAF3IP3 TRAF3 interacting protein 3
TREM1 triggering receptor expressed on myeloid cells 1
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSKS testis-specific serine kinase substrate
TSPAN9 tetraspanin 9
USP29 ubiquitin specific peptidase 29
WNT16 wingless-type MMTV integration site family, member 16
WNT3 wingless-type MMTV integration site family, member 3
ZNF155 zinc finger protein 155
ZNF280A zinc finger protein 280A
ZNF44 zinc finger protein 44
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADGRF1 adhesion G protein-coupled receptor F1
ADGRG6 adhesion G protein-coupled receptor G6
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANP32A-IT1 ANP32A intronic transcript 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
C19ORF40 chromosome 19 open reading frame 40
CEP112 centrosomal protein 112kDa
CHD8 chromodomain helicase DNA binding protein 8
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CIR1 corepressor interacting with RBPJ, 1
CISH cytokine inducible SH2-containing protein
CLEC2B C-type lectin domain family 2, member B
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CXCL3 chemokine (C-X-C motif) ligand 3
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND4C DENN/MADD domain containing 4C
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EN2 engrailed homeobox 2
ERF Ets2 repressor factor
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJC1 gap junction protein, gamma 1, 45kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GNL1 guanine nucleotide binding protein-like 1
GREB1L growth regulation by estrogen in breast cancer-like
HOXA1 homeobox A1
HOXB5 homeobox B5
HSPA2 heat shock 70kDa protein 2
IGSF3 immunoglobulin superfamily, member 3
INPPL1 inositol polyphosphate phosphatase-like 1
IREB2 iron-responsive element binding protein 2
IRF6 interferon regulatory factor 6
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCTD15 potassium channel tetramerization domain containing 15
KIAA0319L KIAA0319-like
KIAA0753 KIAA0753
L2HGDH L-2-hydroxyglutarate dehydrogenase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMCD1 LIM and cysteine-rich domains 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LYPD3 LY6/PLAUR domain containing 3
MBTD1 mbt domain containing 1
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5E 5'-nucleotidase, ecto (CD73)
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OTUD3 OTU deubiquitinase 3
OVGP1 oviductal glycoprotein 1, 120kDa
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLK2 polo-like kinase 2
PLXNA3 plexin A3
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRR4 proline rich 4 (lacrimal)
PTPRE protein tyrosine phosphatase, receptor type, E
RAB5B RAB5B, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
SAV1 salvador family WW domain containing protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SPTBN2 spectrin, beta, non-erythrocytic 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUN2 Sad1 and UNC84 domain containing 2
TBP TATA box binding protein
TGIF1 TGFB-induced factor homeobox 1
TMC5 transmembrane channel-like 5
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZNF197 zinc finger protein 197
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768