cefapirin-7142 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the cefapirin-7142 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEN apoptosis enhancing nuclease
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASF1A anti-silencing function 1A histone chaperone
ATP11A ATPase, class VI, type 11A
AVL9 AVL9 homolog (S. cerevisiase)
BAIAP2 BAI1-associated protein 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BTN3A1 butyrophilin, subfamily 3, member A1
CDH7 cadherin 7, type 2
CDHR2 cadherin-related family member 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP68 centrosomal protein 68kDa
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRCP CGRP receptor component
CSNK1E casein kinase 1, epsilon
CTSK cathepsin K
CYLD cylindromatosis (turban tumor syndrome)
DBF4B DBF4 zinc finger B
DFNB31 deafness, autosomal recessive 31
DGCR8 DGCR8 microprocessor complex subunit
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DVL2 dishevelled segment polarity protein 2
ERP44 endoplasmic reticulum protein 44
EXOC7 exocyst complex component 7
FBXL15 F-box and leucine-rich repeat protein 15
FGFR1 fibroblast growth factor receptor 1
FLJ11292
FLOT1 flotillin 1
FUZ fuzzy planar cell polarity protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPC1 glypican 1
GPR107 G protein-coupled receptor 107
GRAMD4 GRAM domain containing 4
HEATR6 HEAT repeat containing 6
HLX H2.0-like homeobox
HOXA4 homeobox A4
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INADL InaD-like (Drosophila)
ITGB5 integrin, beta 5
ITPKC inositol-trisphosphate 3-kinase C
KAT8 K(lysine) acetyltransferase 8
KDM7A lysine (K)-specific demethylase 7A
KIF5C kinesin family member 5C
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LIMK1 LIM domain kinase 1
MAP1S microtubule-associated protein 1S
MAPK7 mitogen-activated protein kinase 7
MLH3 mutL homolog 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPPE1 metallophosphoesterase 1
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYOZ3 myozenin 3
NCOA2 nuclear receptor coactivator 2
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUMA1 nuclear mitotic apparatus protein 1
ONECUT2 one cut homeobox 2
OVGP1 oviductal glycoprotein 1, 120kDa
PDE12 phosphodiesterase 12
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PLK4 polo-like kinase 4
PRSS16 protease, serine, 16 (thymus)
PTBP2 polypyrimidine tract binding protein 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB35 RAB35, member RAS oncogene family
RNF121 ring finger protein 121
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SFTPB surfactant protein B
SPAG7 sperm associated antigen 7
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TFG TRK-fused gene
THOC5 THO complex 5
TMEM53 transmembrane protein 53
TMEM8B transmembrane protein 8B
TP53TG1 TP53 target 1 (non-protein coding)
TRIM9 tripartite motif containing 9
TTC12 tetratricopeptide repeat domain 12
TXK TXK tyrosine kinase
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WNK1 WNK lysine deficient protein kinase 1
XYLB xylulokinase homolog (H. influenzae)
ZNF10 zinc finger protein 10
ZNF224 zinc finger protein 224
ZNF276 zinc finger protein 276
ZNF528 zinc finger protein 528
ZNF701 zinc finger protein 701
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
ADGRF1 adhesion G protein-coupled receptor F1
ALPK1 alpha-kinase 1
ANAPC2 anaphase promoting complex subunit 2
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD36 ankyrin repeat domain 36
ASB13 ankyrin repeat and SOCS box containing 13
ATP13A2 ATPase type 13A2
BACE1 beta-site APP-cleaving enzyme 1
BAK1 BCL2-antagonist/killer 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
C17ORF85 chromosome 17 open reading frame 85
C1ORF159 chromosome 1 open reading frame 159
C3ORF18 chromosome 3 open reading frame 18
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN5 calpain 5
CASP7 caspase 7, apoptosis-related cysteine peptidase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPOX coproporphyrinogen oxidase
CSK c-src tyrosine kinase
DCLRE1A DNA cross-link repair 1A
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELOVL4 ELOVL fatty acid elongase 4
ERO1L ERO1-like (S. cerevisiae)
ESRP2 epithelial splicing regulatory protein 2
EVPL envoplakin
FAM114A2 family with sequence similarity 114, member A2
FAM127B family with sequence similarity 127, member B
FHOD1 formin homology 2 domain containing 1
GAB2 GRB2-associated binding protein 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H2BI histone cluster 1, H2bi
HOXC8 homeobox C8
IFT88 intraflagellar transport 88
IREB2 iron-responsive element binding protein 2
JUP junction plakoglobin
KCTD7 potassium channel tetramerization domain containing 7
KIAA0513 KIAA0513
KLHL3 kelch-like family member 3
KPTN kaptin (actin binding protein)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANBA mannosidase, beta A, lysosomal
MBD5 methyl-CpG binding domain protein 5
MEIS1 Meis homeobox 1
MUC3B mucin 3B, cell surface associated
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PGS1 phosphatidylglycerophosphate synthase 1
PLD2 phospholipase D2
POLH polymerase (DNA directed), eta
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCD protein kinase C, delta
PROSER1 proline and serine rich 1
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SALL2 spalt-like transcription factor 2
SCRN3 secernin 3
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMYD5 SMYD family member 5
SNHG20 small nucleolar RNA host gene 20
SOD3 superoxide dismutase 3, extracellular
SPATA7 spermatogenesis associated 7
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
STK19 serine/threonine kinase 19
STX1A syntaxin 1A (brain)
TBX19 T-box 19
THOC6 THO complex 6
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TNS2 tensin 2
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TTC31 tetratricopeptide repeat domain 31
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UBTD1 ubiquitin domain containing 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XPA xeroderma pigmentosum, complementation group A
ZFP36 ZFP36 ring finger protein
ZNF177 zinc finger protein 177
ZNF629 zinc finger protein 629