cd40 ligand deficiency Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A combined T cell and B cell immunodeficiency that is a X-linked immunodeficiency with hyperimmunoglobulin M (XHIM) affecting isotype switching and is caused by the absence of CD40 ligand which is normally expressed on activated CD4+ T cells. Individuals with this mutation are unable to switch from IgM to IgG, IgA and IgE. (Human Disease Ontology, DOID_0060022)
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11 genes co-occuring with the disease cd40 ligand deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RIMBP2 RIMS binding protein 2 1.86186
CD40LG CD40 ligand 1.70816
CD40 CD40 molecule, TNF receptor superfamily member 5 1.20007
HAX1 HCLS1 associated protein X-1 0.908142
CD276 CD276 molecule 0.495793
CARD17 caspase recruitment domain family, member 17 0.395235
CD79A CD79a molecule, immunoglobulin-associated alpha 0.367779
PRF1 perforin 1 (pore forming protein) 0.324823
CSF3 colony stimulating factor 3 (granulocyte) 0.278297
CHGA chromogranin A 0.259477
ELANE elastase, neutrophil expressed 0.230409