ccr4-not complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, including repression and activation of mRNA initiation, control of mRNA elongation, and the deadenylation and subsequent degradation of mRNA. In Saccharomyces the CCR4-NOT complex comprises a core complex of 9 proteins (Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p), Caf4p, Caf16p, and several less well characterized proteins. (Gene Ontology, GO_0030014)
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74 proteins co-occuring with the ccr4-not complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CNOT1 CCR4-NOT transcription complex, subunit 1 3.30338
CNOT7 CCR4-NOT transcription complex, subunit 7 2.78636
CNOT6 CCR4-NOT transcription complex, subunit 6 2.50994
CNOT3 CCR4-NOT transcription complex, subunit 3 2.37879
CNOT6L CCR4-NOT transcription complex, subunit 6-like 2.29631
CNOT8 CCR4-NOT transcription complex, subunit 8 2.27986
CNOT4 CCR4-NOT transcription complex, subunit 4 2.03724
CNOT11 CCR4-NOT transcription complex, subunit 11 1.75339
DEDD death effector domain containing 1.73624
CNOT2 CCR4-NOT transcription complex, subunit 2 1.52823
TOB1 transducer of ERBB2, 1 1.41306
CNOT10 CCR4-NOT transcription complex, subunit 10 1.3763
BTG4 B-cell translocation gene 4 1.36913
PARN poly(A)-specific ribonuclease 1.29746
NANOS2 nanos homolog 2 (Drosophila) 1.29692
CHAF1A chromatin assembly factor 1, subunit A (p150) 1.26868
PABPC1 poly(A) binding protein, cytoplasmic 1 1.16081
BTG2 BTG family, member 2 1.15979
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.05791
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 1.05488
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.03078
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.932658
GIGYF2 GRB10 interacting GYF protein 2 0.901818
BTG3 BTG family, member 3 0.870885
ZFP36L2 ZFP36 ring finger protein-like 2 0.857095
NANOS3 nanos homolog 3 (Drosophila) 0.852961
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.804313
PUM1 pumilio RNA-binding family member 1 0.781412
YTHDC1 YTH domain containing 1 0.776384
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.756799
TOB2 transducer of ERBB2, 2 0.737363
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.729732
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.728836
NANOS1 nanos homolog 1 (Drosophila) 0.723919
ZFP36L1 ZFP36 ring finger protein-like 1 0.687264
PUM2 pumilio RNA-binding family member 2 0.641858
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.615437
PRPF31 pre-mRNA processing factor 31 0.604862
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.595173
SMG6 SMG6 nonsense mediated mRNA decay factor 0.590553
TBP TATA box binding protein 0.548122
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.536594
FGD1 FYVE, RhoGEF and PH domain containing 1 0.51694
APTX aprataxin 0.498636
POMP proteasome maturation protein 0.455214
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.452427
HOXA1 homeobox A1 0.4425
NME1-NME2 NME1-NME2 readthrough 0.437356
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.430647
MAML1 mastermind-like 1 (Drosophila) 0.428678
UBE2K ubiquitin-conjugating enzyme E2K 0.420036
UBE2S ubiquitin-conjugating enzyme E2S 0.397811
COX17 COX17 cytochrome c oxidase copper chaperone 0.395098
LSM1 LSM1, U6 small nuclear RNA associated 0.375434
CAND1 cullin-associated and neddylation-dissociated 1 0.372749
LARGE like-glycosyltransferase 0.361277
MSMB microseminoprotein, beta- 0.34645
DCC DCC netrin 1 receptor 0.341907
CDC73 cell division cycle 73 0.329837
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.329461
KIAA0101 KIAA0101 0.326453
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.31596
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0.302912
PRMT1 protein arginine methyltransferase 1 0.236683
NGDN neuroguidin, EIF4E binding protein 0.227397
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.22385
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.223497
RRM1 ribonucleotide reductase M1 0.214714
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.207451
HDAC5 histone deacetylase 5 0.201335
EIF4E eukaryotic translation initiation factor 4E 0.189222
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 0.183631
UBE3A ubiquitin protein ligase E3A 0.179167
ATN1 atrophin 1 0.169604