catalytic step 2 spliceosome Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. (Gene Ontology, GO_0071013)
External Link http://amigo.geneontology.org/amigo/term/GO:0071013
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Genes

79 proteins localized to the catalytic step 2 spliceosome cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ALYREF Aly/REF export factor
AQR aquarius intron-binding spliceosomal factor
CACTIN cactin, spliceosome C complex subunit
CDC40 cell division cycle 40
CDC5L cell division cycle 5-like
CRNKL1 crooked neck pre-mRNA splicing factor 1
CWC15 CWC15 spliceosome-associated protein
CWC22 CWC22 spliceosome-associated protein
CWC27 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DGCR14 DiGeorge syndrome critical region gene 14
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF4A3 eukaryotic translation initiation factor 4A3
FRG1 FSHD region gene 1
GPATCH1 G patch domain containing 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAGOHB mago-nashi homolog B (Drosophila)
PABPC1 poly(A) binding protein, cytoplasmic 1
PLRG1 pleiotropic regulator 1
PNN pinin, desmosome associated protein
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRPF19 pre-mRNA processing factor 19
PRPF4B pre-mRNA processing factor 4B
PRPF6 pre-mRNA processing factor 6
PRPF8 pre-mRNA processing factor 8
RALY RALY heterogeneous nuclear ribonucleoprotein
RBM22 RNA binding motif protein 22
RBM8A RNA binding motif protein 8A
RBMX RNA binding motif protein, X-linked
SART1 squamous cell carcinoma antigen recognized by T cells
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3A3 splicing factor 3a, subunit 3, 60kDa
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPF small nuclear ribonucleoprotein polypeptide F
SNRPG small nuclear ribonucleoprotein polypeptide G
SNW1 SNW domain containing 1
SRRM1 serine/arginine repetitive matrix 1
SRRM2 serine/arginine repetitive matrix 2
SRSF1 serine/arginine-rich splicing factor 1
SYF2 SYF2 pre-mRNA-splicing factor
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TFIP11 tuftelin interacting protein 11
WDR83 WD repeat domain 83
XAB2 XPA binding protein 2
ZCCHC8 zinc finger, CCHC domain containing 8