cascades Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

202 genes co-occuring with the biological term cascades in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ACVR1 activin A receptor, type I
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB1 adrenoceptor beta 1
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ANGPT2 angiopoietin 2
AQP4 aquaporin 4
ARL5A ADP-ribosylation factor-like 5A
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARR3 arrestin 3, retinal (X-arrestin)
ATR ATR serine/threonine kinase
ATXN2 ataxin 2
BCAR1 breast cancer anti-estrogen resistance 1
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
C9ORF72 chromosome 9 open reading frame 72
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMP cathelicidin antimicrobial peptide
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBX5 chromobox homolog 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD177 CD177 molecule
CD28 CD28 molecule
CD46 CD46 molecule, complement regulatory protein
CD48 CD48 molecule
CD6 CD6 molecule
CDC42 cell division cycle 42
CDC42SE2 CDC42 small effector 2
CDK1 cyclin-dependent kinase 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHEK1 checkpoint kinase 1
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CREB1 cAMP responsive element binding protein 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CTGF connective tissue growth factor
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DCD dermcidin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DLG4 discs, large homolog 4 (Drosophila)
DPP4 dipeptidyl-peptidase 4
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZR ezrin
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FADD Fas (TNFRSF6)-associated via death domain
FAM162A family with sequence similarity 162, member A
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCRL3 Fc receptor-like 3
FLT1 fms-related tyrosine kinase 1
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GSK3B glycogen synthase kinase 3 beta
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HCAR3 hydroxycarboxylic acid receptor 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL15 interleukin 15
IL1B interleukin 1, beta
IL6 interleukin 6
IL7 interleukin 7
ILK integrin-linked kinase
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAG1 jagged 1
JUN jun proto-oncogene
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MIR143 microRNA 143
MIR34A microRNA 34a
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEFM neurofilament, medium polypeptide
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRD1 nardilysin (N-arginine dibasic convertase)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARVB parvin, beta
PAX3 paired box 3
PEBP1 phosphatidylethanolamine binding protein 1
PHB prohibitin
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLD2 phospholipase D2
PPARA peroxisome proliferator-activated receptor alpha
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTX3 pentraxin 3, long
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHOA ras homolog family member A
RHOG ras homolog family member G
RIT1 Ras-like without CAAX 1
RIT2 Ras-like without CAAX 2
RNLS renalase, FAD-dependent amine oxidase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPGR retinitis pigmentosa GTPase regulator
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX1 runt-related transcription factor 1
SCD5 stearoyl-CoA desaturase 5
SFRP2 secreted frizzled-related protein 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TANK TRAF family member-associated NFKB activator
TARDBP TAR DNA binding protein
TBK1 TANK-binding kinase 1
TBKBP1 TBK1 binding protein 1
TCL1A T-cell leukemia/lymphoma 1A
TFF2 trefoil factor 2
TGFB1 transforming growth factor, beta 1
THOC1 THO complex 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TWIST1 twist family bHLH transcription factor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor