carotid body Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000204)
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Genes

172 proteins co-occuring with the tissue carotid body in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 2.49442
CBS cystathionine-beta-synthase 2.44084
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 2.27286
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.17448
TH tyrosine hydroxylase 2.10859
KCNK9 potassium channel, two pore domain subfamily K, member 9 1.80564
PGLS 6-phosphogluconolactonase 1.73828
HMOX2 heme oxygenase 2 1.67206
TAC1 tachykinin, precursor 1 1.60018
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.51807
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 1.36678
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.3645
GDNF glial cell derived neurotrophic factor 1.23539
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.18423
DRD2 dopamine receptor D2 1.18201
CALCA calcitonin-related polypeptide alpha 1.18157
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 1.13988
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 1.12571
NPY neuropeptide Y 1.12084
CHGA chromogranin A 1.10624
KLK8 kallikrein-related peptidase 8 1.10314
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.05061
CYBB cytochrome b-245, beta polypeptide 1.04357
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.02294
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.998037
ACSF2 acyl-CoA synthetase family member 2 0.9889
GGN gametogenetin 0.977616
LBR lamin B receptor 0.974149
NGB neuroglobin 0.942645
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.918633
GAL galanin/GMAP prepropeptide 0.914361
ENO2 enolase 2 (gamma, neuronal) 0.907535
EDN1 endothelin 1 0.888405
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.885015
PANX1 pannexin 1 0.870639
NPS neuropeptide S 0.868951
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.852527
HOXA3 homeobox A3 0.850845
CTH cystathionine gamma-lyase 0.843706
TACR1 tachykinin receptor 1 0.836575
CBR4 carbonyl reductase 4 0.803544
KCNU1 potassium channel, subfamily U, member 1 0.75371
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.749166
PDYN prodynorphin 0.744627
CYBA cytochrome b-245, alpha polypeptide 0.725685
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.717882
DPP6 dipeptidyl-peptidase 6 0.712959
SST somatostatin 0.712139
VIP vasoactive intestinal peptide 0.696172
KCNK4 potassium channel, two pore domain subfamily K, member 4 0.686776
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.685959
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.654618
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.652994
ARMC10 armadillo repeat containing 10 0.652589
MME membrane metallo-endopeptidase 0.640833
ASIC1 acid sensing (proton gated) ion channel 1 0.63719
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.627889
EDNRA endothelin receptor type A 0.627081
SYP synaptophysin 0.590839
TMEM127 transmembrane protein 127 0.590036
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.580017
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.572418
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.564833
GRP gastrin-releasing peptide 0.562441
RET ret proto-oncogene 0.561644
EDAR ectodysplasin A receptor 0.55607
EPO erythropoietin 0.552888
MED25 mediator complex subunit 25 0.549312
LPXN leupaxin 0.548517
EGLN3 egl-9 family hypoxia-inducible factor 3 0.546136
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.540981
CSN3 casein kappa 0.539793
NTS neurotensin 0.535438
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.522405
NPPA natriuretic peptide A 0.517284
TPH1 tryptophan hydroxylase 1 0.516891
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.50471
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.50471
CHAT choline O-acetyltransferase 0.501965
BDNF brain-derived neurotrophic factor 0.501574
ADORA1 adenosine A1 receptor 0.498048
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.494918
FOS FBJ murine osteosarcoma viral oncogene homolog 0.493745
ARTN artemin 0.489057
IL1R1 interleukin 1 receptor, type I 0.488667
ISCU iron-sulfur cluster assembly enzyme 0.488667
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.472315
ABR active BCR-related 0.469599
PENK proenkephalin 0.463787
TRIM37 tripartite motif containing 37 0.461078
PNMT phenylethanolamine N-methyltransferase 0.446807
NGF nerve growth factor (beta polypeptide) 0.445268
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.442962
SRRM1 serine/arginine repetitive matrix 1 0.435672
NEFL neurofilament, light polypeptide 0.427254
FAT4 FAT atypical cadherin 4 0.423436
LEPR leptin receptor 0.420385
SOD2 superoxide dismutase 2, mitochondrial 0.411631
ASCL1 achaete-scute family bHLH transcription factor 1 0.41087
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.408212
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.407832
NOS1 nitric oxide synthase 1 (neuronal) 0.402144
ADCY10 adenylate cyclase 10 (soluble) 0.401765
ACHE acetylcholinesterase (Yt blood group) 0.393819
HAND2 heart and neural crest derivatives expressed 2 0.393064
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.389666
SLC7A4 solute carrier family 7, member 4 0.361155
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.354826
THEM5 thioesterase superfamily member 5 0.353712
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.350743
NLRP1 NLR family, pyrin domain containing 1 0.348148
TFIP11 tuftelin interacting protein 11 0.345188
ADM adrenomedullin 0.341126
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.33965
INS insulin 0.338177
NOS3 nitric oxide synthase 3 (endothelial cell) 0.335968
HDC histidine decarboxylase 0.331194
GPR4 G protein-coupled receptor 4 0.326798
XPR1 xenotropic and polytropic retrovirus receptor 1 0.326798
GUCY2C guanylate cyclase 2C 0.32205
NTSR1 neurotensin receptor 1 (high affinity) 0.321685
NPR1 natriuretic peptide receptor 1 0.320227
SPX spexin hormone 0.316951
B3GAT1 beta-1,3-glucuronyltransferase 1 0.315135
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.31332
PDE4A phosphodiesterase 4A, cAMP-specific 0.309697
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.304279
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.294223
AVP arginine vasopressin 0.293508
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.291365
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.286381
PRCC papillary renal cell carcinoma (translocation-associated) 0.284607
PLCB2 phospholipase C, beta 2 0.283899
GALR3 galanin receptor 3 0.282837
MLX MLX, MAX dimerization protein 0.282483
EDA ectodysplasin A 0.282483
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.280012
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.279659
CBLN1 cerebellin 1 precursor 0.276846
ADORA2A adenosine A2a receptor 0.276495
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.2723
ADORA2B adenosine A2b receptor 0.268828
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.268828
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.268137
ASIC3 acid sensing (proton gated) ion channel 3 0.267791
SCN2A sodium channel, voltage gated, type II alpha subunit 0.266757
GJB1 gap junction protein, beta 1, 32kDa 0.262986
ACE angiotensin I converting enzyme 0.259929
F9 coagulation factor IX 0.259591
VEGFA vascular endothelial growth factor A 0.255567
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.253578
FOSL1 FOS-like antigen 1 0.251934
IL6R interleukin 6 receptor 0.251606
RHOD ras homolog family member D 0.249006
TUBB tubulin, beta class I 0.24486
HIF3A hypoxia inducible factor 3, alpha subunit 0.241438
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.23176
CA2 carbonic anhydrase II 0.23176
BCHE butyrylcholinesterase 0.231206
CTBP2 C-terminal binding protein 2 0.228764
MSX2 msh homeobox 2 0.227707
EGLN2 egl-9 family hypoxia-inducible factor 2 0.227707
SFTPA1 surfactant protein A1 0.226926
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.2259
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.223419
LEP leptin 0.220831
CYGB cytoglobin 0.220604
LTF lactotransferrin 0.217762
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.214954
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.213291
CCNB2 cyclin B2 0.213112
FGF2 fibroblast growth factor 2 (basic) 0.213112