carbenoxolone-3014 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the carbenoxolone-3014 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
ADAM28 ADAM metallopeptidase domain 28
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOE apolipoprotein E
ARSD arylsulfatase D
B9D1 B9 protein domain 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP8B bone morphogenetic protein 8b
BPI bactericidal/permeability-increasing protein
BTG3 BTG family, member 3
C10ORF12 chromosome 10 open reading frame 12
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH10 cadherin 10, type 2 (T2-cadherin)
CFP complement factor properdin
CHMP6 charged multivesicular body protein 6
CLIP4 CAP-GLY domain containing linker protein family, member 4
CSH2 chorionic somatomammotropin hormone 2
CTRL chymotrypsin-like
DESI2 desumoylating isopeptidase 2
DGCR8 DGCR8 microprocessor complex subunit
DSTYK dual serine/threonine and tyrosine protein kinase
EFNB3 ephrin-B3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EIF1 eukaryotic translation initiation factor 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPAS1 endothelial PAS domain protein 1
ESR2 estrogen receptor 2 (ER beta)
EXTL3 exostosin-like glycosyltransferase 3
FCAR Fc fragment of IgA receptor
FDPS farnesyl diphosphate synthase
FGF20 fibroblast growth factor 20
GMPR guanosine monophosphate reductase
GPC4 glypican 4
GPR132 G protein-coupled receptor 132
GVINP1 GTPase, very large interferon inducible pseudogene 1
HIPK3 homeodomain interacting protein kinase 3
INO80B INO80 complex subunit B
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JAG1 jagged 1
JAM2 junctional adhesion molecule 2
KHK ketohexokinase (fructokinase)
LAMP1 lysosomal-associated membrane protein 1
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LIMD2 LIM domain containing 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMOD1 leiomodin 1 (smooth muscle)
LRP2 low density lipoprotein receptor-related protein 2
MBD2 methyl-CpG binding domain protein 2
MDM4 MDM4, p53 regulator
MFSD6 major facilitator superfamily domain containing 6
MVP major vault protein
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NF2 neurofibromin 2 (merlin)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMT1 N-myristoyltransferase 1
NOL10 nucleolar protein 10
ONECUT2 one cut homeobox 2
OPRL1 opiate receptor-like 1
PACRG PARK2 co-regulated
PBX2 pre-B-cell leukemia homeobox 2
PCDH9 protocadherin 9
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEK2 pleckstrin 2
PML promyelocytic leukemia
PRKCI protein kinase C, iota
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYCRL pyrroline-5-carboxylate reductase-like
QKI QKI, KH domain containing, RNA binding
RAB11B RAB11B, member RAS oncogene family
RB1 retinoblastoma 1
RDX radixin
RNGTT RNA guanylyltransferase and 5'-phosphatase
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGMS1 sphingomyelin synthase 1
SLAMF7 SLAM family member 7
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC35F5 solute carrier family 35, member F5
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMAD5 SMAD family member 5
SPRR2B small proline-rich protein 2B
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TMPRSS4 transmembrane protease, serine 4
TNNT3 troponin T type 3 (skeletal, fast)
TUBA4B tubulin, alpha 4b
WDR4 WD repeat domain 4
WIPI2 WD repeat domain, phosphoinositide interacting 2
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBTB20 zinc finger and BTB domain containing 20
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF492 zinc finger protein 492
ZNF75D zinc finger protein 75D
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADGRD2 adhesion G protein-coupled receptor D2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALOX12 arachidonate 12-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ANO2 anoctamin 2, calcium activated chloride channel
ANXA2P3 annexin A2 pseudogene 3
BIRC3 baculoviral IAP repeat containing 3
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C22ORF46 chromosome 22 open reading frame 46
C3ORF14 chromosome 3 open reading frame 14
CCDC33 coiled-coil domain containing 33
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK20 cyclin-dependent kinase 20
CFAP45 cilia and flagella associated protein 45
CHI3L2 chitinase 3-like 2
CHML choroideremia-like (Rab escort protein 2)
CLCF1 cardiotrophin-like cytokine factor 1
CLEC10A C-type lectin domain family 10, member A
CNN1 calponin 1, basic, smooth muscle
CTSV cathepsin V
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ELSPBP1 epididymal sperm binding protein 1
ERC2-IT1 ERC2 intronic transcript 1
FBXL2 F-box and leucine-rich repeat protein 2
FBXL7 F-box and leucine-rich repeat protein 7
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GPR35 G protein-coupled receptor 35
HDAC7 histone deacetylase 7
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HOXA2 homeobox A2
HOXB9 homeobox B9
HOXC8 homeobox C8
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFT22 intraflagellar transport 22
IGH immunoglobulin heavy locus
IL12B interleukin 12B
IL37 interleukin 37
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1456 KIAA1456
KLK11 kallikrein-related peptidase 11
LOC57399 uncharacterized gastric protein ZA52P
LOXL3 lysyl oxidase-like 3
MAP6D1 MAP6 domain containing 1
MGP matrix Gla protein
MRAS muscle RAS oncogene homolog
MYH4 myosin, heavy chain 4, skeletal muscle
NNAT neuronatin
NPIPB15 nuclear pore complex interacting protein family, member B15
NPM3 nucleophosmin/nucleoplasmin 3
OSBP2 oxysterol binding protein 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDH12 protocadherin 12
PDE12 phosphodiesterase 12
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PMP22 peripheral myelin protein 22
POLH polymerase (DNA directed), eta
PRDM12 PR domain containing 12
PRICKLE3 prickle homolog 3 (Drosophila)
PROL1 proline rich, lacrimal 1
PROX1 prospero homeobox 1
PRR7 proline rich 7 (synaptic)
PYGB phosphorylase, glycogen; brain
QSER1 glutamine and serine rich 1
REC8 REC8 meiotic recombination protein
RIBC2 RIB43A domain with coiled-coils 2
RIMBP2 RIMS binding protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL13P5 ribosomal protein L13 pseudogene 5
SCN5A sodium channel, voltage gated, type V alpha subunit
SCRT1 scratch family zinc finger 1
SLC16A6 solute carrier family 16, member 6
SLC17A2 solute carrier family 17, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TIAM2 T-cell lymphoma invasion and metastasis 2
TMC5 transmembrane channel-like 5
TMEM209 transmembrane protein 209
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TTC30A tetratricopeptide repeat domain 30A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VWA1 von Willebrand factor A domain containing 1
ZNF280A zinc finger protein 280A
ZNF385D zinc finger protein 385D
ZNF415 zinc finger protein 415
ZNF484 zinc finger protein 484
ZNF552 zinc finger protein 552