calcium pantothenate-4775 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the calcium pantothenate-4775 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRL4 adhesion G protein-coupled receptor L4
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BCL2L1 BCL2-like 1
BRD4 bromodomain containing 4
C14ORF93 chromosome 14 open reading frame 93
C2 complement component 2
CD34 CD34 molecule
CD86 CD86 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLSPN claspin
CLUAP1 clusterin associated protein 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DBP D site of albumin promoter (albumin D-box) binding protein
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DMTN dematin actin binding protein
EFNA3 ephrin-A3
EPHA1 EPH receptor A1
FAM131A family with sequence similarity 131, member A
FOXN3 forkhead box N3
GFI1 growth factor independent 1 transcription repressor
GHRHR growth hormone releasing hormone receptor
GPR1 G protein-coupled receptor 1
GPR153 G protein-coupled receptor 153
HFE hemochromatosis
HOXA4 homeobox A4
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGLJ3 immunoglobulin lambda joining 3
IL1RN interleukin 1 receptor antagonist
INE1 inactivation escape 1 (non-protein coding)
ITGB7 integrin, beta 7
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMC2 laminin, gamma 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MEGF8 multiple EGF-like-domains 8
METTL7A methyltransferase like 7A
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MON2 MON2 homolog (S. cerevisiae)
NAT6 N-acetyltransferase 6 (GCN5-related)
NCAM1 neural cell adhesion molecule 1
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRF1 nuclear respiratory factor 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
ODAM odontogenic, ameloblast asssociated
OLFML2A olfactomedin-like 2A
OPRL1 opiate receptor-like 1
OSBPL3 oxysterol binding protein-like 3
PCDHA5 protocadherin alpha 5
PGLYRP4 peptidoglycan recognition protein 4
PLCL2 phospholipase C-like 2
PLXNB3 plexin B3
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PSEN2 presenilin 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD51B RAD51 paralog B
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPL35A ribosomal protein L35a
RPS3A ribosomal protein S3A
SENP5 SUMO1/sentrin specific peptidase 5
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETD8 SET domain containing (lysine methyltransferase) 8
SFTPB surfactant protein B
SIGLEC8 sialic acid binding Ig-like lectin 8
SIK3 SIK family kinase 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SUGP1 SURP and G patch domain containing 1
TAGLN3 transgelin 3
THAP3 THAP domain containing, apoptosis associated protein 3
TLDC1 TBC/LysM-associated domain containing 1
TRIM68 tripartite motif containing 68
TSPAN2 tetraspanin 2
TTLL4 tubulin tyrosine ligase-like family member 4
UBA7 ubiquitin-like modifier activating enzyme 7
UPK3B uroplakin 3B
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZIM2 zinc finger, imprinted 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF141 zinc finger protein 141

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AIDA axin interactor, dorsalization associated
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCAR3 breast cancer anti-estrogen resistance 3
BCL2L2 BCL2-like 2
BTD biotinidase
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CBR4 carbonyl reductase 4
CCDC9 coiled-coil domain containing 9
CCNL2 cyclin L2
CDADC1 cytidine and dCMP deaminase domain containing 1
CDR2L cerebellar degeneration-related protein 2-like
CENPJ centromere protein J
CEP97 centrosomal protein 97kDa
CFAP44 cilia and flagella associated protein 44
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIR1 corepressor interacting with RBPJ, 1
CLDN15 claudin 15
CORT cortistatin
CTSK cathepsin K
CYBA cytochrome b-245, alpha polypeptide
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
EPHA2 EPH receptor A2
FILIP1L filamin A interacting protein 1-like
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMHA1 histocompatibility (minor) HA-1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IRF6 interferon regulatory factor 6
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
KIF13A kinesin family member 13A
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
METTL4 methyltransferase like 4
MFSD12 major facilitator superfamily domain containing 12
MTERF4 mitochondrial transcription termination factor 4
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PCDHB3 protocadherin beta 3
PDHX pyruvate dehydrogenase complex, component X
PLA2G3 phospholipase A2, group III
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRMT7 protein arginine methyltransferase 7
PROS1 protein S (alpha)
PRR7 proline rich 7 (synaptic)
PYGL phosphorylase, glycogen, liver
QPCT glutaminyl-peptide cyclotransferase
RAB3A RAB3A, member RAS oncogene family
RHBDD3 rhomboid domain containing 3
ROM1 retinal outer segment membrane protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A2 S100 calcium binding protein A2
SAMD9 sterile alpha motif domain containing 9
SAV1 salvador family WW domain containing protein 1
SCAI suppressor of cancer cell invasion
SCN1B sodium channel, voltage gated, type I beta subunit
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC41A3 solute carrier family 41, member 3
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STX10 syntaxin 10
TMCO3 transmembrane and coiled-coil domains 3
TMEM134 transmembrane protein 134
TMEM45A transmembrane protein 45A
TOM1 target of myb1 (chicken)
TPST1 tyrosylprotein sulfotransferase 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBA3D tubulin, alpha 3d
UBE2O ubiquitin-conjugating enzyme E2O
UPP1 uridine phosphorylase 1
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF134 zinc finger protein 134
ZNF324 zinc finger protein 324
ZNF446 zinc finger protein 446
ZNF557 zinc finger protein 557
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF654 zinc finger protein 654