cajal body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. (Gene Ontology, GO_0015030)
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Genes

213 proteins co-occuring with the cajal body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
COIL coilin 3.1616
CBS cystathionine-beta-synthase 2.48987
REM2 RAS (RAD and GEM)-like GTP binding 2 2.11876
SMN2 survival of motor neuron 2, centromeric 2.09473
FBLL1 fibrillarin-like 1 1.79973
SMN1 survival of motor neuron 1, telomeric 1.79973
SRSF2 serine/arginine-rich splicing factor 2 1.45647
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 1.40186
NPAT nuclear protein, ataxia-telangiectasia locus 1.31142
WRAP53 WD repeat containing, antisense to TP53 1.20189
GEMIN4 gem (nuclear organelle) associated protein 4 1.18184
NOP10 NOP10 ribonucleoprotein 1.11735
STRAP serine/threonine kinase receptor associated protein 1.05136
HINFP histone H4 transcription factor 1.0408
PHAX phosphorylated adaptor for RNA export 1.02779
GEMIN5 gem (nuclear organelle) associated protein 5 1.00153
USPL1 ubiquitin specific peptidase like 1 0.966956
GEMIN6 gem (nuclear organelle) associated protein 6 0.946382
NHP2 NHP2 ribonucleoprotein 0.937377
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 0.936432
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 0.910647
REM1 RAS (RAD and GEM)-like GTP-binding 1 0.90832
ZPR1 ZPR1 zinc finger 0.870885
LSM11 LSM11, U7 small nuclear RNA associated 0.868586
MAPT microtubule-associated protein tau 0.858933
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.855257
GEMIN7 gem (nuclear organelle) associated protein 7 0.840105
FRG1 FSHD region gene 1 0.830466
CASP8AP2 caspase 8 associated protein 2 0.827254
GMIP GEM interacting protein 0.826794
LSM10 LSM10, U7 small nuclear RNA associated 0.821746
DKC1 dyskeratosis congenita 1, dyskerin 0.813487
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.794687
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.777755
CDK2 cyclin-dependent kinase 2 0.760433
SLBP stem-loop binding protein 0.747737
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.745477
NCL nucleolin 0.744122
GEMIN8 gem (nuclear organelle) associated protein 8 0.736464
GEM GTP binding protein overexpressed in skeletal muscle 0.733319
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 0.730628
NOP58 NOP58 ribonucleoprotein 0.726599
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.725705
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.725258
FAM118B family with sequence similarity 118, member B 0.725258
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 0.721688
TARDBP TAR DNA binding protein 0.711022
CLPSL1 colipase-like 1 0.70439
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.703949
FAM71B family with sequence similarity 71, member B 0.703067
LAT linker for activation of T cells 0.701744
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.699983
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.690326
MVD mevalonate (diphospho) decarboxylase 0.688576
DCK deoxycytidine kinase 0.685954
KIF9 kinesin family member 9 0.675065
FUS FUS RNA binding protein 0.672894
PIAS4 protein inhibitor of activated STAT, 4 0.668559
RRAD Ras-related associated with diabetes 0.657326
RD3 retinal degeneration 3 0.652159
GMNN geminin, DNA replication inhibitor 0.641429
TERT telomerase reverse transcriptase 0.637578
WDR20 WD repeat domain 20 0.632878
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.629465
RPP38 ribonuclease P/MRP 38kDa subunit 0.620104
STX8 syntaxin 8 0.617133
EML1 echinoderm microtubule associated protein like 1 0.617133
PML promyelocytic leukemia 0.613742
INTS4 integrator complex subunit 4 0.613742
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.603596
NOP56 NOP56 ribonucleoprotein 0.598117
RBM28 RNA binding motif protein 28 0.558871
PRPF6 pre-mRNA processing factor 6 0.521841
BLNK B-cell linker 0.518573
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 0.515716
RRM1 ribonucleotide reductase M1 0.51327
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 0.512047
RAP2B RAP2B, member of RAS oncogene family 0.510011
C2CD4A C2 calcium-dependent domain containing 4A 0.510011
SNUPN snurportin 1 0.50757
SAR1A secretion associated, Ras related GTPase 1A 0.502693
LAT2 linker for activation of T cells family, member 2 0.501476
C2CD4B C2 calcium-dependent domain containing 4B 0.497015
RHEBL1 Ras homolog enriched in brain like 1 0.483676
LRRC75A-AS1 LRRC75A antisense RNA 1 0.48287
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.471609
PAPD5 PAP associated domain containing 5 0.4676
SRRT serrate, RNA effector molecule 0.462798
IGH immunoglobulin heavy locus 0.461599
POLI polymerase (DNA directed) iota 0.461199
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.454816
BRWD1 bromodomain and WD repeat domain containing 1 0.453223
XPO1 exportin 1 0.448848
UBL5 ubiquitin-like 5 0.434591
PSPC1 paraspeckle component 1 0.431829
ARF3 ADP-ribosylation factor 3 0.427891
MAL mal, T-cell differentiation protein 0.426711
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.425531
RAB1B RAB1B, member RAS oncogene family 0.425138
RRM2 ribonucleotide reductase M2 0.422782
SYMPK symplekin 0.42082
ZNF638 zinc finger protein 638 0.420036
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 0.419252
GSK3A glycogen synthase kinase 3 alpha 0.417294
SYK spleen tyrosine kinase 0.413382
HIST1H4H histone cluster 1, H4h 0.398587
HIST2H4B histone cluster 2, H4b 0.398587
HIST1H4A histone cluster 1, H4a 0.398587
HIST1H4B histone cluster 1, H4b 0.398587
HIST1H4C histone cluster 1, H4c 0.398587
HIST1H4E histone cluster 1, H4e 0.398587
HIST1H4D histone cluster 1, H4d 0.398587
HIST1H4K histone cluster 1, H4k 0.398587
HIST1H4J histone cluster 1, H4j 0.398587
HIST1H4I histone cluster 1, H4i 0.398587
HIST1H4L histone cluster 1, H4l 0.398199
HIST2H4A histone cluster 2, H4a 0.398199
HIST1H4F histone cluster 1, H4f 0.398199
HIST4H4 histone cluster 4, H4 0.398199
RNMT RNA (guanine-7-) methyltransferase 0.393936
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.391228
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 0.388137
YTHDC1 YTH domain containing 1 0.386593
EWSR1 EWS RNA-binding protein 1 0.37966
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.378507
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.378122
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.377354
LSG1 large 60S subunit nuclear export GTPase 1 0.37697
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.37697
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.37697
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.374666
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.372366
RASD1 RAS, dexamethasone-induced 1 0.372366
PHF1 PHD finger protein 1 0.370067
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.365477
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 0.363567
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.357847
RPP14 ribonuclease P/MRP 14kDa subunit 0.353662
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.353662
CCNH cyclin H 0.351382
CSK c-src tyrosine kinase 0.349105
PCNA proliferating cell nuclear antigen 0.341529
RPP21 ribonuclease P/MRP 21kDa subunit 0.339261
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.338884
HIPK2 homeodomain interacting protein kinase 2 0.338884
PA2G4 proliferation-associated 2G4, 38kDa 0.336996
HRAS Harvey rat sarcoma viral oncogene homolog 0.324576
LCK LCK proto-oncogene, Src family tyrosine kinase 0.318205
SP100 SP100 nuclear antigen 0.311851
WBP11 WW domain binding protein 11 0.311851
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.307004
AMIGO2 adhesion molecule with Ig-like domain 2 0.30254
ATXN1 ataxin 1 0.294007
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.290678
TRIM22 tripartite motif containing 22 0.289569
TP53 tumor protein p53 0.284769
UBE2M ubiquitin-conjugating enzyme E2M 0.282558
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.282558
RAB40AL RAB40A, member RAS oncogene family-like 0.280349
PXDN peroxidasin 0.277774
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.275936
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.274468
WNT8B wingless-type MMTV integration site family, member 8B 0.273
JUN jun proto-oncogene 0.260931
UBTF upstream binding transcription factor, RNA polymerase I 0.260931
VRK2 vaccinia related kinase 2 0.260566
GP6 glycoprotein VI (platelet) 0.259837
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 0.258745
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.252202
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.250751
PLLP plasmolipin 0.248578
MX1 MX dynamin-like GTPase 1 0.245323
KRAS Kirsten rat sarcoma viral oncogene homolog 0.243519
AK6 adenylate kinase 6 0.243158
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.242437
LYN LYN proto-oncogene, Src family tyrosine kinase 0.232029
PSPH phosphoserine phosphatase 0.227397
CTNNBL1 catenin, beta like 1 0.225622
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.224558
SMS spermine synthase 0.212974
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.208825
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.208825
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.205399
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.203699
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.203699
TOP1 topoisomerase (DNA) I 0.199325
BCR breakpoint cluster region 0.198658
CYR61 cysteine-rich, angiogenic inducer, 61 0.19307
DAXX death-domain associated protein 0.192423
PARN poly(A)-specific ribonuclease 0.189857
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.185777
MYBBP1A MYB binding protein (P160) 1a 0.179167
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.177439
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.177154
PABPN1 poly(A) binding protein, nuclear 1 0.174635
VAV1 vav 1 guanine nucleotide exchange factor 0.173543
PQBP1 polyglutamine binding protein 1 0.169859
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.169604
HIPK3 homeodomain interacting protein kinase 3 0.169099
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.168598
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.167611
MIR221 microRNA 221 0.167366
RBM14 RNA binding motif protein 14 0.167125
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.166884
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.165932
GRB2 growth factor receptor-bound protein 2 0.16477
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.164089
PLCG1 phospholipase C, gamma 1 0.163865
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.16298
CACYBP calcyclin binding protein 0.162546
CDK7 cyclin-dependent kinase 7 0.162117
CD1E CD1e molecule 0.160456
PSIP1 PC4 and SFRS1 interacting protein 1 0.159268