c-fiber Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated. (Gene Ontology, GO_0044299)
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Genes

152 proteins co-occuring with the c-fiber cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TAC1 tachykinin, precursor 1 2.89721
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.71621
CALCA calcitonin-related polypeptide alpha 2.22692
KNG1 kininogen 1 2.20148
NPS neuropeptide S 2.14059
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.00621
TACR1 tachykinin receptor 1 1.70754
TACR2 tachykinin receptor 2 1.62236
RARS arginyl-tRNA synthetase 1.4757
TRPC7 transient receptor potential cation channel, subfamily C, member 7 1.44347
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 1.39461
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.35156
SCN10A sodium channel, voltage gated, type X alpha subunit 1.34883
OPRM1 opioid receptor, mu 1 1.34774
NGF nerve growth factor (beta polypeptide) 1.28409
ALLC allantoicase 1.22984
GAL galanin/GMAP prepropeptide 1.2262
MRGPRD MAS-related GPR, member D 1.18748
FOS FBJ murine osteosarcoma viral oncogene homolog 1.16901
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.15313
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.15313
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.12807
MME membrane metallo-endopeptidase 1.11429
FBXO17 F-box protein 17 1.09035
SARS seryl-tRNA synthetase 1.07562
PNOC prepronociceptin 0.974198
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.963588
PHGDH phosphoglycerate dehydrogenase 0.947333
SCN3A sodium channel, voltage gated, type III alpha subunit 0.940689
GDNF glial cell derived neurotrophic factor 0.90832
CNR1 cannabinoid receptor 1 (brain) 0.899962
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.840564
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.838728
VIP vasoactive intestinal peptide 0.831384
DRGX dorsal root ganglia homeobox 0.822664
HRH1 histamine receptor H1 0.808441
HRH3 histamine receptor H3 0.79652
ARTN artemin 0.786902
ADORA1 adenosine A1 receptor 0.778669
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.775928
PDYN prodynorphin 0.746381
SST somatostatin 0.729732
NPY neuropeptide Y 0.729284
CCK cholecystokinin 0.723919
BDKRB1 bradykinin receptor B1 0.719015
U2SURP U2 snRNP-associated SURP domain containing 0.711908
OPRL1 opiate receptor-like 1 0.657757
FSCN1 fascin actin-bundling protein 1 0.63544
GSE1 Gse1 coiled-coil protein 0.591812
SALL4 spalt-like transcription factor 4 0.586361
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.580086
BDNF brain-derived neurotrophic factor 0.577581
GRM1 glutamate receptor, metabotropic 1 0.573411
ATF3 activating transcription factor 3 0.564262
SCG2 secretogranin II 0.561772
LEP leptin 0.555145
ACE angiotensin I converting enzyme 0.530438
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.527979
GALR2 galanin receptor 2 0.525931
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.512047
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.512047
GALR1 galanin receptor 1 0.504318
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.495395
GRIK1 glutamate receptor, ionotropic, kainate 1 0.492157
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.47844
UBE4A ubiquitination factor E4A 0.476831
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.474018
IL1B interleukin 1, beta 0.469604
AMH anti-Mullerian hormone 0.468401
ANK1 ankyrin 1, erythrocytic 0.466799
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.464798
CCKBR cholecystokinin B receptor 0.444085
DEGS2 delta(4)-desaturase, sphingolipid 2 0.441708
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.435775
UBD ubiquitin D 0.425138
ACRV1 acrosomal vesicle protein 1 0.42396
ACSM2A acyl-CoA synthetase medium-chain family member 2A 0.415728
GRP gastrin-releasing peptide 0.412601
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.400527
NRG1 neuregulin 1 0.397811
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.395873
POMC proopiomelanocortin 0.39471
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.392001
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.377354
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.369301
TRIM37 tripartite motif containing 37 0.353282
TNF tumor necrosis factor 0.352142
STOML3 stomatin (EPB72)-like 3 0.347587
CALCRL calcitonin receptor-like 0.342664
LAP3 leucine aminopeptidase 3 0.342664
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.341151
EPHB1 EPH receptor B1 0.332472
TACR3 tachykinin receptor 3 0.327956
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.325327
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.324951
CUTA cutA divalent cation tolerance homolog (E. coli) 0.32345
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.321575
AIF1 allograft inflammatory factor 1 0.314091
CAPNS1 calpain, small subunit 1 0.305515
CST7 cystatin F (leukocystatin) 0.293637
ACPT acid phosphatase, testicular 0.293267
CCKAR cholecystokinin A receptor 0.289569
RPIA ribose 5-phosphate isomerase A 0.284401
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.282926
NTF3 neurotrophin 3 0.272267
MON1A MON1 secretory trafficking family member A 0.269701
LCA10 lung carcinoma-associated 10 0.269701
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.267871
TH tyrosine hydroxylase 0.263485
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.260931
GAP43 growth associated protein 43 0.257289
ACPP acid phosphatase, prostate 0.250389
FGF12 fibroblast growth factor 12 0.243879
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.23776
CXCL8 chemokine (C-X-C motif) ligand 8 0.236683
PDE5A phosphodiesterase 5A, cGMP-specific 0.235607
PENK proenkephalin 0.234891
MSTO1 misato 1, mitochondrial distribution and morphology regulator 0.234533
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.233101
CPZ carboxypeptidase Z 0.227752
GRPR gastrin-releasing peptide receptor 0.227041
NRTN neurturin 0.225267
NTF4 neurotrophin 4 0.218563
GRM5 glutamate receptor, metabotropic 5 0.214714
NNAT neuronatin 0.20574
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.199325
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.197993
GDF5 growth differentiation factor 5 0.197993
BDKRB2 bradykinin receptor B2 0.196669
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.196669
PSENEN presenilin enhancer gamma secretase subunit 0.18796
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.185777
CRH corticotropin releasing hormone 0.185469
GRM4 glutamate receptor, metabotropic 4 0.183631
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.182723
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 0.181823
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.177724
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.17687
PYY peptide YY 0.175745
ALB albumin 0.174087
CHRM4 cholinergic receptor, muscarinic 4 0.173543
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.167125
SAA1 serum amyloid A1 0.166884
JMJD6 jumonji domain containing 6 0.166167
NTS neurotensin 0.166167
PTH2 parathyroid hormone 2 0.164315
JUN jun proto-oncogene 0.164089
INS insulin 0.161693
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.161484
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.160053
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.158129
CMKLR1 chemerin chemokine-like receptor 1 0.157397