butoconazole-6288 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the butoconazole-6288 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABHD2 abhydrolase domain containing 2
AIM2 absent in melanoma 2
AKR1C1 aldo-keto reductase family 1, member C1
ALAS1 5'-aminolevulinate synthase 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOM apolipoprotein M
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARNT aryl hydrocarbon receptor nuclear translocator
ARR3 arrestin 3, retinal (X-arrestin)
ATF3 activating transcription factor 3
ATXN7L1 ataxin 7-like 1
BAHCC1 BAH domain and coiled-coil containing 1
CCDC88A coiled-coil domain containing 88A
CCNA1 cyclin A1
CD58 CD58 molecule
CDH8 cadherin 8, type 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNOT4 CCR4-NOT transcription complex, subunit 4
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DLX4 distal-less homeobox 4
DVL2 dishevelled segment polarity protein 2
EFNA3 ephrin-A3
EFNB3 ephrin-B3
EMILIN2 elastin microfibril interfacer 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB2 EPH receptor B2
FAM118A family with sequence similarity 118, member A
FGL1 fibrinogen-like 1
GATA2 GATA binding protein 2
GOLGA2 golgin A2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMG20B high mobility group 20B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HUS1 HUS1 checkpoint homolog (S. pombe)
IDS iduronate 2-sulfatase
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT9 keratin 9, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LEF1 lymphoid enhancer-binding factor 1
MSC musculin
MUC1 mucin 1, cell surface associated
MYOZ3 myozenin 3
NRXN3 neurexin 3
NUMA1 nuclear mitotic apparatus protein 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
PBOV1 prostate and breast cancer overexpressed 1
PCNX pecanex homolog (Drosophila)
PDGFA platelet-derived growth factor alpha polypeptide
PICALM phosphatidylinositol binding clathrin assembly protein
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PRDX2 peroxiredoxin 2
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTCH1 patched 1
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RIN3 Ras and Rab interactor 3
RNF122 ring finger protein 122
RPL10 ribosomal protein L10
RUNDC3A RUN domain containing 3A
SAMD4A sterile alpha motif domain containing 4A
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH2D3A SH2 domain containing 3A
SIX3 SIX homeobox 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX13 sorting nexin 13
SP4 Sp4 transcription factor
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STOM stomatin
TBC1D30 TBC1 domain family, member 30
TCP10L t-complex 10-like
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNNT2 troponin T type 2 (cardiac)
TRABD TraB domain containing
TRGV5 T cell receptor gamma variable 5
TTLL3 tubulin tyrosine ligase-like family member 3
TULP1 tubby like protein 1
VEZT vezatin, adherens junctions transmembrane protein
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAT1 adenosine deaminase, tRNA-specific 1
AGBL5 ATP/GTP binding protein-like 5
ANOS1 anosmin 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C10ORF88 chromosome 10 open reading frame 88
C1ORF115 chromosome 1 open reading frame 115
C1RL complement component 1, r subcomponent-like
C9ORF116 chromosome 9 open reading frame 116
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC47 coiled-coil domain containing 47
CCRL2 chemokine (C-C motif) receptor-like 2
CGREF1 cell growth regulator with EF-hand domain 1
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CSRNP3 cysteine-serine-rich nuclear protein 3
CST6 cystatin E/M
CXADR coxsackie virus and adenovirus receptor
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DONSON downstream neighbor of SON
EDC3 enhancer of mRNA decapping 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGF epidermal growth factor
EN1 engrailed homeobox 1
FAM102A family with sequence similarity 102, member A
FAM188A family with sequence similarity 188, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGFBP1 fibroblast growth factor binding protein 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSD1 fibronectin type III and SPRY domain containing 1
GBAP1 glucosidase, beta, acid pseudogene 1
GJC1 gap junction protein, gamma 1, 45kDa
GYS1 glycogen synthase 1 (muscle)
H1F0 H1 histone family, member 0
HDAC4 histone deacetylase 4
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD7 potassium channel tetramerization domain containing 7
KIFAP3 kinesin-associated protein 3
LPAR6 lysophosphatidic acid receptor 6
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MCMBP minichromosome maintenance complex binding protein
MED24 mediator complex subunit 24
MICALL2 MICAL-like 2
MN1 meningioma (disrupted in balanced translocation) 1
MOXD1 monooxygenase, DBH-like 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MTG1 mitochondrial ribosome-associated GTPase 1
MUC7 mucin 7, secreted
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NID2 nidogen 2 (osteonidogen)
NLRX1 NLR family member X1
NPM3 nucleophosmin/nucleoplasmin 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PMPCA peptidase (mitochondrial processing) alpha
PRAME preferentially expressed antigen in melanoma
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRPH peripherin
PRR7 proline rich 7 (synaptic)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RFX7 regulatory factor X, 7
RNF31 ring finger protein 31
RPAP2 RNA polymerase II associated protein 2
RUSC2 RUN and SH3 domain containing 2
SDC3 syndecan 3
SETBP1 SET binding protein 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SND1-IT1 SND1 intronic transcript 1
STARD13 StAR-related lipid transfer (START) domain containing 13
TAGLN3 transgelin 3
TAOK1 TAO kinase 1
TBL3 transducin (beta)-like 3
TEX10 testis expressed 10
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM2 transmembrane protein 2
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNRC6B trinucleotide repeat containing 6B
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
ULK1 unc-51 like autophagy activating kinase 1
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
UROS uroporphyrinogen III synthase
WASF1 WAS protein family, member 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZC3H12A zinc finger CCCH-type containing 12A
ZMAT3 zinc finger, matrin-type 3
ZNF212 zinc finger protein 212
ZNF253 zinc finger protein 253
ZNF385D zinc finger protein 385D
ZNF442 zinc finger protein 442
ZNF84 zinc finger protein 84