buspirone-2637 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the buspirone-2637 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
AIM1L absent in melanoma 1-like
ALCAM activated leukocyte cell adhesion molecule
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AQP7 aquaporin 7
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATF6B activating transcription factor 6 beta
C2CD2L C2CD2-like
CALML5 calmodulin-like 5
CCRL2 chemokine (C-C motif) receptor-like 2
CDC14B cell division cycle 14B
CFAP44 cilia and flagella associated protein 44
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
DFNB31 deafness, autosomal recessive 31
DIEXF digestive organ expansion factor homolog (zebrafish)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ERC2-IT1 ERC2 intronic transcript 1
EWSR1 EWS RNA-binding protein 1
FBXO41 F-box protein 41
FGFR4 fibroblast growth factor receptor 4
FKBP1B FK506 binding protein 1B, 12.6 kDa
FXYD2 FXYD domain containing ion transport regulator 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
HES2 hes family bHLH transcription factor 2
HIST1H2BM histone cluster 1, H2bm
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IBSP integrin-binding sialoprotein
IDS iduronate 2-sulfatase
IL5RA interleukin 5 receptor, alpha
ING1 inhibitor of growth family, member 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRS2 insulin receptor substrate 2
KIAA0125 KIAA0125
KIAA1107 KIAA1107
LAMP1 lysosomal-associated membrane protein 1
LMF2 lipase maturation factor 2
LOC100286895 cell division cycle 27 homolog pseudogene
MAPK13 mitogen-activated protein kinase 13
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MR1 major histocompatibility complex, class I-related
MTCP1 mature T-cell proliferation 1
MYF5 myogenic factor 5
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOTCH3 notch 3
NOVA2 neuro-oncological ventral antigen 2
NPM3 nucleophosmin/nucleoplasmin 3
OBSL1 obscurin-like 1
PCDH12 protocadherin 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PENK proenkephalin
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK4 polo-like kinase 4
POU6F1 POU class 6 homeobox 1
PRKCE protein kinase C, epsilon
PSG4 pregnancy specific beta-1-glycoprotein 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB28 RAB28, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS10 regulator of G-protein signaling 10
RIMS2 regulating synaptic membrane exocytosis 2
RNF39 ring finger protein 39
RNF43 ring finger protein 43
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUSC2 RUN and SH3 domain containing 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
STK3 serine/threonine kinase 3
SYMPK symplekin
SYN3 synapsin III
SYNDIG1 synapse differentiation inducing 1
TAOK2 TAO kinase 2
TAZ tafazzin
TBC1D2B TBC1 domain family, member 2B
TBCD tubulin folding cofactor D
TBX6 T-box 6
TLE4 transducin-like enhancer of split 4
TM4SF1 transmembrane 4 L six family member 1
TMCC2 transmembrane and coiled-coil domain family 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UBOX5 U-box domain containing 5
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UTRN utrophin
WDR59 WD repeat domain 59
ZBTB17 zinc finger and BTB domain containing 17
ZNF37BP zinc finger protein 37B, pseudogene
ZNF45 zinc finger protein 45

decreased expression

Symbol Name
ANKRD40 ankyrin repeat domain 40
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
C12ORF4 chromosome 12 open reading frame 4
C19ORF40 chromosome 19 open reading frame 40
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CENPJ centromere protein J
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDIT3 DNA-damage-inducible transcript 3
DGKE diacylglycerol kinase, epsilon 64kDa
DSCAM Down syndrome cell adhesion molecule
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM186A family with sequence similarity 186, member A
FAM212B family with sequence similarity 212, member B
FER fer (fps/fes related) tyrosine kinase
FIP1L1 factor interacting with PAPOLA and CPSF1
FKBP14 FK506 binding protein 14, 22 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HSPA1L heat shock 70kDa protein 1-like
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KIF13B kinesin family member 13B
KIZ kizuna centrosomal protein
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX1 LIM homeobox 1
LMNB1 lamin B1
LRP6 low density lipoprotein receptor-related protein 6
LRRC8E leucine rich repeat containing 8 family, member E
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYPD1 LY6/PLAUR domain containing 1
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NKX3-2 NK3 homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLA2G3 phospholipase A2, group III
PLEKHO2 pleckstrin homology domain containing, family O member 2
PODXL2 podocalyxin-like 2
PRR14L proline rich 14-like
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF146 ring finger protein 146
SDC3 syndecan 3
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC16A6 solute carrier family 16, member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAI2 snail family zinc finger 2
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STRN striatin, calmodulin binding protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCHH trichohyalin
TCTA T-cell leukemia translocation altered
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRIM21 tripartite motif containing 21
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF205 zinc finger protein 205
ZNF34 zinc finger protein 34
ZNF571 zinc finger protein 571
ZNF574 zinc finger protein 574
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF767P zinc finger family member 767, pseudogene