brush border membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The portion of the plasma membrane surrounding the brush border. (Gene Ontology, GO_0031526)
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Genes

278 proteins co-occuring with the brush border membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LCT lactase 2.42082
ANPEP alanyl (membrane) aminopeptidase 2.26279
ALPPL2 alkaline phosphatase, placental-like 2 2.21266
ALPP alkaline phosphatase, placental 2.21266
ALPL alkaline phosphatase, liver/bone/kidney 2.21116
SI sucrase-isomaltase (alpha-glucosidase) 1.94531
LAP3 leucine aminopeptidase 3 1.89939
TREH trehalase (brush-border membrane glycoprotein) 1.7964
PTH parathyroid hormone 1.75147
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 1.66962
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.6259
DPP4 dipeptidyl-peptidase 4 1.51525
GGT1 gamma-glutamyltransferase 1 1.47796
FGF23 fibroblast growth factor 23 1.435
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.4125
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 1.38738
PDZK1 PDZ domain containing 1 1.3363
CRY1 cryptochrome circadian clock 1 1.30282
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.26868
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 1.2539
ALPI alkaline phosphatase, intestinal 1.23818
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.23766
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 1.2288
DNAH8 dynein, axonemal, heavy chain 8 1.22205
NPC1L1 NPC1-like 1 1.21428
SLC46A1 solute carrier family 46 (folate transporter), member 1 1.21169
LRP2 low density lipoprotein receptor-related protein 2 1.19983
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 1.17876
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 1.17722
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.17055
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 1.13574
GIF gastric intrinsic factor (vitamin B synthesis) 1.12143
MEP1B meprin A, beta 1.11276
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 1.09493
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.09035
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 1.08984
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.07917
MGAM maltase-glucoamylase 1.07866
MEP1A meprin A, alpha (PABA peptide hydrolase) 1.07055
TMPRSS15 transmembrane protease, serine 15 1.06954
ACE angiotensin I converting enzyme 1.05892
MME membrane metallo-endopeptidase 1.05287
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.03378
CYBRD1 cytochrome b reductase 1 1.01536
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.988782
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.987317
GPR148 G protein-coupled receptor 148 0.977104
KIAA1919 KIAA1919 0.965993
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.95831
GANAB glucosidase, alpha; neutral AB 0.956874
GGT6 gamma-glutamyltransferase 6 0.924197
GGT7 gamma-glutamyltransferase 7 0.912977
GGT5 gamma-glutamyltransferase 5 0.912511
GGTLC1 gamma-glutamyltransferase light chain 1 0.912511
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.892093
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.879633
INS insulin 0.873647
PHEX phosphate regulating endopeptidase homolog, X-linked 0.851583
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 0.850665
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.823123
FABP6 fatty acid binding protein 6, ileal 0.795145
GANC glucosidase, alpha; neutral C 0.790564
S100G S100 calcium binding protein G 0.789191
FOLR1 folate receptor 1 (adult) 0.764982
NT5E 5'-nucleotidase, ecto (CD73) 0.759978
FOLR2 folate receptor 2 (fetal) 0.758615
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.750904
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.747737
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.747737
PLB1 phospholipase B1 0.745929
PLA2G1B phospholipase A2, group IB (pancreas) 0.736014
ALB albumin 0.729284
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 0.721688
GUCY2C guanylate cyclase 2C 0.720797
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.71857
TF transferrin 0.712795
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.693393
LTF lactotransferrin 0.688576
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.685954
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.68508
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.684644
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.684207
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.681591
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 0.677238
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 0.666827
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.658188
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.650869
HEPH hephaestin 0.643144
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.634586
EZR ezrin 0.620954
SLC17A4 solute carrier family 17, member 4 0.61883
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.615861
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 0.609509
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.595593
RBSN rabenosyn, RAB effector 0.595593
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 0.589714
AQP7 aquaporin 7 0.588456
EMP1 epithelial membrane protein 1 0.588037
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.588037
PDZD3 PDZ domain containing 3 0.571745
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.567585
BIN2 bridging integrator 2 0.564677
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.564677
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.564262
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.561358
GGT2 gamma-glutamyltransferase 2 0.560528
NPR1 natriuretic peptide receptor 1 0.554318
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.551838
REN renin 0.548535
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 0.53906
CSN1S1 casein alpha s1 0.535772
NPPA natriuretic peptide A 0.534951
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 0.524294
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.524294
TBRG1 transforming growth factor beta regulator 1 0.518573
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 0.513677
GLS2 glutaminase 2 (liver, mitochondrial) 0.512862
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 0.507977
CAT catalase 0.497826
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.488923
NPEPPS aminopeptidase puromycin sensitive 0.488519
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 0.485693
GLS glutaminase 0.483273
SCARB1 scavenger receptor class B, member 1 0.482064
CEL carboxyl ester lipase 0.478843
ITLN1 intelectin 1 (galactofuranose binding) 0.477636
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.475223
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.474018
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.473617
TOB1 transducer of ERBB2, 1 0.469604
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.4672
MUC3A mucin 3A, cell surface associated 0.4672
ACE2 angiotensin I converting enzyme 2 0.463598
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.462398
AQP1 aquaporin 1 (Colton blood group) 0.4608
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.4608
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.460401
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 0.458404
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.456809
MGP matrix Gla protein 0.453223
GAA glucosidase, alpha; acid 0.4425
GPX5 glutathione peroxidase 5 0.441312
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.440916
SLC38A5 solute carrier family 38, member 5 0.438146
GPX4 glutathione peroxidase 4 0.43538
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.434985
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.429859
PNLIP pancreatic lipase 0.427891
LPO lactoperoxidase 0.427497
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 0.426318
LEAP2 liver expressed antimicrobial peptide 2 0.425138
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 0.424745
GPX1 glutathione peroxidase 1 0.424353
FBP1 fructose-1,6-bisphosphatase 1 0.417685
CRISP1 cysteine-rich secretory protein 1 0.41612
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 0.41221
UBQLN3 ubiquilin 3 0.41221
ASL argininosuccinate lyase 0.403637
SOD2 superoxide dismutase 2, mitochondrial 0.40247
SCGB2A1 secretoglobin, family 2A, member 1 0.400139
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.398587
PYY peptide YY 0.390841
ENGASE endo-beta-N-acetylglucosaminidase 0.385051
G6PD glucose-6-phosphate dehydrogenase 0.381584
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.378507
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.377354
GCG glucagon 0.372749
SLC38A1 solute carrier family 38, member 1 0.372366
DPEP1 dipeptidase 1 (renal) 0.370833
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.37045
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.369301
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.362804
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.359371
MYO1A myosin IA 0.358609
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.358228
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.357467
ADCY2 adenylate cyclase 2 (brain) 0.352901
FUT2 fucosyltransferase 2 (secretor status included) 0.352901
OAZ1 ornithine decarboxylase antizyme 1 0.351382
ICMT isoprenylcysteine carboxyl methyltransferase 0.350243
MMEL1 membrane metallo-endopeptidase-like 1 0.349484
STON1 stonin 1 0.348346
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 0.34645
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 0.346071
CCK cholecystokinin 0.340773
IGBP1 immunoglobulin (CD79A) binding protein 1 0.339639
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.332848
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.328708
FTH1 ferritin, heavy polypeptide 1 0.326453
IGF1 insulin-like growth factor 1 (somatomedin C) 0.324951
GSR glutathione reductase 0.323825
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.320077
LMBR1L limb development membrane protein 1-like 0.320077
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.318953
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.315212
FGD1 FYVE, RhoGEF and PH domain containing 1 0.309986
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.30626
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.302912
PTHLH parathyroid hormone-like hormone 0.301425
FTL ferritin, light polypeptide 0.29994
SRA1 steroid receptor RNA activator 1 0.297713
MEPE matrix extracellular phosphoglycoprotein 0.296972
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.29623
B2M beta-2-microglobulin 0.294748
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 0.290308
SLC51A solute carrier family 51, alpha subunit 0.289938
ACTG1 actin gamma 1 0.287352
SHF Src homology 2 domain containing F 0.286983
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.284769
KL klotho 0.283663
GSTA3 glutathione S-transferase alpha 3 0.283295
GSTA4 glutathione S-transferase alpha 4 0.281453
GSTA2 glutathione S-transferase alpha 2 0.281453
FADS1 fatty acid desaturase 1 0.27998
LALBA lactalbumin, alpha- 0.279612
GSTA1 glutathione S-transferase alpha 1 0.279245
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.274468
SLC16A6 solute carrier family 16, member 6 0.272267
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.269701
ANXA2 annexin A2 0.269335
WTIP Wilms tumor 1 interacting protein 0.263485
ODC1 ornithine decarboxylase 1 0.254017
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.246407
CYLD cylindromatosis (turban tumor syndrome) 0.246407
CDX2 caudal type homeobox 2 0.245323
PDZK1IP1 PDZK1 interacting protein 1 0.243879
GSS glutathione synthetase 0.241716
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.240636
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.238837
PITRM1 pitrilysin metallopeptidase 1 0.238119
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.234174
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.232744
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.230245
MDH1 malate dehydrogenase 1, NAD (soluble) 0.229532
INA internexin neuronal intermediate filament protein, alpha 0.229176
STRBP spermatid perinuclear RNA binding protein 0.226331
SLC22A10 solute carrier family 22, member 10 0.224913
TGS1 trimethylguanosine synthase 1 0.223497
SLC26A1 solute carrier family 26 (anion exchanger), member 1 0.222436
IP6K2 inositol hexakisphosphate kinase 2 0.215063
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 0.214366
KNG1 kininogen 1 0.213669
CES1 carboxylesterase 1 0.212974
CRY2 cryptochrome circadian clock 2 0.211587
LYZ lysozyme 0.205399
SNHG12 small nucleolar RNA host gene 12 0.205399
SDF4 stromal cell derived factor 4 0.204378
AMY2A amylase, alpha 2A (pancreatic) 0.200999
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.199325
TFRC transferrin receptor 0.197993
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 0.195681
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 0.194698
AGTR1 angiotensin II receptor, type 1 0.193394
LGALS4 lectin, galactoside-binding, soluble, 4 0.19307
TMEM27 transmembrane protein 27 0.191135
IP6K1 inositol hexakisphosphate kinase 1 0.189857
STC1 stanniocalcin 1 0.185777
PEMT phosphatidylethanolamine N-methyltransferase 0.183328
ACTB actin, beta 0.180634
AQP9 aquaporin 9 0.179752
CALB1 calbindin 1, 28kDa 0.179459
MUC2 mucin 2, oligomeric mucus/gel-forming 0.172201
MUC12 mucin 12, cell surface associated 0.17141
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.170629
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.170114
CALCA calcitonin-related polypeptide alpha 0.168847
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.168598
STARD5 StAR-related lipid transfer (START) domain containing 5 0.168349
PLAC1 placenta-specific 1 0.168101
ZMPSTE24 zinc metallopeptidase STE24 0.1632
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.162546
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.16233
G6PC glucose-6-phosphatase, catalytic subunit 0.161068
MUC17 mucin 17, cell surface associated 0.158692
MVK mevalonate kinase 0.158129
GRIK4 glutamate receptor, ionotropic, kainate 4 0.157943
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.15776
SLCO4C1 solute carrier organic anion transporter family, member 4C1 0.157039