brisc complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains. (Gene Ontology, GO_0070552)
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21 proteins co-occuring with the brisc complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
FAM175B family with sequence similarity 175, member B 2.6656
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.8752
BABAM1 BRISC and BRCA1 A complex member 1 1.66598
CMC4 C-x(9)-C motif containing 4 1.58795
UIMC1 ubiquitin interaction motif containing 1 1.52089
THAP5 THAP domain containing 5 1.52089
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 1.3896
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 1.22724
ATF5 activating transcription factor 5 0.94876
UBD ubiquitin D 0.79148
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.759069
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.738263
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.657326
COPS5 COP9 signalosome subunit 5 0.554732
BRCA1 breast cancer 1, early onset 0.531668
JUND jun D proto-oncogene 0.50757
MECOM MDS1 and EVI1 complex locus 0.489327
KLF10 Kruppel-like factor 10 0.478843
NLRP3 NLR family, pyrin domain containing 3 0.414164
ATF4 activating transcription factor 4 0.329461
CARD17 caspase recruitment domain family, member 17 0.190175