bone resorption disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A bone remodeling disease that results in an abnormal decrease of bone density or mass. (Human Disease Ontology, DOID_0080011)
Similar Terms
Downloads & Tools

Genes

499 genes co-occuring with the disease bone resorption disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
BGLAP bone gamma-carboxyglutamate (gla) protein 3.31142
PTH parathyroid hormone 3.14222
ALPP alkaline phosphatase, placental 2.81715
ALPPL2 alkaline phosphatase, placental-like 2 2.81715
ALPL alkaline phosphatase, liver/bone/kidney 2.81652
CALCA calcitonin-related polypeptide alpha 2.67093
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.56333
ESR1 estrogen receptor 1 2.39744
SOST sclerostin 2.3644
CTSK cathepsin K 2.31276
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 2.19403
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.15354
RUNX2 runt-related transcription factor 2 2.14378
LRP5 low density lipoprotein receptor-related protein 5 2.08729
IGF1 insulin-like growth factor 1 (somatomedin C) 2.00056
BMP2 bone morphogenetic protein 2 1.95112
ACPP acid phosphatase, prostate 1.94407
SP7 Sp7 transcription factor 1.87975
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.84408
COL1A1 collagen, type I, alpha 1 1.793
COL1A2 collagen, type I, alpha 2 1.67412
SLC51A solute carrier family 51, alpha subunit 1.62291
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.58269
CALCR calcitonin receptor 1.56755
ESR2 estrogen receptor 2 (ER beta) 1.54142
LEP leptin 1.48252
SPP1 secreted phosphoprotein 1 1.46935
MGAM maltase-glucoamylase 1.46803
SHBG sex hormone-binding globulin 1.43508
IL6 interleukin 6 1.43157
CASR calcium-sensing receptor 1.41577
PTHLH parathyroid hormone-like hormone 1.38297
FDPS farnesyl diphosphate synthase 1.33545
PTH1R parathyroid hormone 1 receptor 1.3145
TNF tumor necrosis factor 1.2582
LRP6 low density lipoprotein receptor-related protein 6 1.2582
TBX1 T-box 1 1.23994
KL klotho 1.23863
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.21825
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.21782
FOS FBJ murine osteosarcoma viral oncogene homolog 1.21305
IBSP integrin-binding sialoprotein 1.19229
TGFB1 transforming growth factor, beta 1 1.18152
GC group-specific component (vitamin D binding protein) 1.1422
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 1.13966
IGFBP3 insulin-like growth factor binding protein 3 1.13755
ALB albumin 1.12952
MRPL49 mitochondrial ribosomal protein L49 1.12952
GCM2 glial cells missing homolog 2 (Drosophila) 1.10636
DCSTAMP dendrocyte expressed seven transmembrane protein 1.10384
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 1.09797
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.08537
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.08495
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.08118
INS insulin 1.07614
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.06732
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.05639
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.05219
PPARG peroxisome proliferator-activated receptor gamma 1.04798
AR androgen receptor 1.0463
TBCA tubulin folding cofactor A 1.04041
KNTC1 kinetochore associated 1 1.02777
ZNF384 zinc finger protein 384 1.02229
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.02229
ZBTB40 zinc finger and BTB domain containing 40 1.0109
CRP C-reactive protein, pentraxin-related 0.997392
IL1B interleukin 1, beta 0.993174
POMC proopiomelanocortin 0.98011
CTSS cathepsin S 0.976323
FGF23 fibroblast growth factor 23 0.952856
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.947852
LCT lactase 0.947019
MGP matrix Gla protein 0.942027
S100G S100 calcium binding protein G 0.942027
NOG noggin 0.904442
WNT16 wingless-type MMTV integration site family, member 16 0.90321
BMP7 bone morphogenetic protein 7 0.878605
OSCAR osteoclast associated, immunoglobulin-like receptor 0.858952
WNT3A wingless-type MMTV integration site family, member 3A 0.858952
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.857315
THSD7A thrombospondin, type I, domain containing 7A 0.850764
WLS wntless Wnt ligand secretion mediator 0.847488
BMP4 bone morphogenetic protein 4 0.841344
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.833968
PLEKHO1 pleckstrin homology domain containing, family O member 1 0.811821
WNT10B wingless-type MMTV integration site family, member 10B 0.81018
MEPE matrix extracellular phosphoglycoprotein 0.806488
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.806077
SFRP1 secreted frizzled-related protein 1 0.806077
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.804436
SEBOX SEBOX homeobox 0.795002
DNAH8 dynein, axonemal, heavy chain 8 0.788852
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.764718
RAP1A RAP1A, member of RAS oncogene family 0.761454
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.755749
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.739082
WRN Werner syndrome, RecQ helicase-like 0.735433
KREMEN2 kringle containing transmembrane protein 2 0.714005
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.711587
SRR serine racemase 0.707559
JUN jun proto-oncogene 0.706754
GGCX gamma-glutamyl carboxylase 0.699919
AHSG alpha-2-HS-glycoprotein 0.693098
SOX6 SRY (sex determining region Y)-box 6 0.691094
TMEM119 transmembrane protein 119 0.689492
TCF4 transcription factor 4 0.688692
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.685091
ATF4 activating transcription factor 4 0.680297
GORAB golgin, RAB6-interacting 0.677504
CCDC170 coiled-coil domain containing 170 0.676308
INSL3 insulin-like 3 (Leydig cell) 0.674315
CA2 carbonic anhydrase II 0.665563
MMP9 matrix metallopeptidase 9 0.659611
PGRMC1 progesterone receptor membrane component 1 0.659215
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.656441
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.655254
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.640645
FRZB frizzled-related protein 0.636708
ZNF410 zinc finger protein 410 0.635528
BMP6 bone morphogenetic protein 6 0.633956
WNT1 wingless-type MMTV integration site family, member 1 0.631598
CSF1R colony stimulating factor 1 receptor 0.621008
CSN1S1 casein alpha s1 0.612792
SIRT1 sirtuin 1 0.607714
IL1RN interleukin 1 receptor antagonist 0.607714
DMRTA1 DMRT-like family A1 0.594064
RXFP2 relaxin/insulin-like family peptide receptor 2 0.590948
MMP13 matrix metallopeptidase 13 0.589779
IL1A interleukin 1, alpha 0.583941
FABP4 fatty acid binding protein 4, adipocyte 0.581606
ZNF467 zinc finger protein 467 0.581606
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.581217
GGPS1 geranylgeranyl diphosphate synthase 1 0.580439
IL11 interleukin 11 0.579661
EGFL6 EGF-like-domain, multiple 6 0.578494
ESRRA estrogen-related receptor alpha 0.577716
OSBPL1A oxysterol binding protein-like 1A 0.577327
FGF2 fibroblast growth factor 2 (basic) 0.576161
NELL1 NEL-like 1 (chicken) 0.574994
ALOX15 arachidonate 15-lipoxygenase 0.572273
APOE apolipoprotein E 0.570329
ADIG adipogenin 0.569163
IAPP islet amyloid polypeptide 0.56722
TMEM135 transmembrane protein 135 0.5645
IPP intracisternal A particle-promoted polypeptide 0.559062
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.557897
IGFBP5 insulin-like growth factor binding protein 5 0.557897
SMS spermine synthase 0.556344
GPATCH1 G patch domain containing 1 0.554791
CDC14B cell division cycle 14B 0.554791
KY kyphoscoliosis peptidase 0.554791
CD4 CD4 molecule 0.547419
LPL lipoprotein lipase 0.546644
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.541605
LOX lysyl oxidase 0.537731
CREB1 cAMP responsive element binding protein 1 0.536957
ZNF446 zinc finger protein 446 0.534248
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.522273
SP1 Sp1 transcription factor 0.521888
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.519575
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.517649
ITGA1 integrin, alpha 1 0.514571
DLX5 distal-less homeobox 5 0.513033
SERHL serine hydrolase-like (pseudogene) 0.505739
THSD4 thrombospondin, type I, domain containing 4 0.498085
SOD2 superoxide dismutase 2, mitochondrial 0.487788
HNF4A hepatocyte nuclear factor 4, alpha 0.487788
SPTBN1 spectrin, beta, non-erythrocytic 1 0.484744
GHRL ghrelin/obestatin prepropeptide 0.480566
NOTCH2 notch 2 0.479427
NOTCH2NL notch 2 N-terminal like 0.476772
GPX1 glutathione peroxidase 1 0.476772
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.476014
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.475255
NOTCH1 notch 1 0.474498
ACE angiotensin I converting enzyme 0.472982
GPR55 G protein-coupled receptor 55 0.471089
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.466928
SRP9 signal recognition particle 9kDa 0.46655
SRP9P1 signal recognition particle 9 pseudogene 1 0.46655
EPHA4 EPH receptor A4 0.465038
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.463527
VAV3 vav 3 guanine nucleotide exchange factor 0.461261
GPX5 glutathione peroxidase 5 0.459751
FSHR follicle stimulating hormone receptor 0.459373
GPX4 glutathione peroxidase 4 0.456355
BGN biglycan 0.455978
B2M beta-2-microglobulin 0.455601
ZDHHC13 zinc finger, DHHC-type containing 13 0.455601
MAPK8 mitogen-activated protein kinase 8 0.454093
DBT dihydrolipoamide branched chain transacylase E2 0.452208
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.450701
NPY neuropeptide Y 0.448064
IL6R interleukin 6 receptor 0.446558
QRFP pyroglutamylated RFamide peptide 0.446558
FOSL1 FOS-like antigen 1 0.443171
CNR1 cannabinoid receptor 1 (brain) 0.442795
CLDN11 claudin 11 0.44129
LEPR leptin receptor 0.436026
WNT5B wingless-type MMTV integration site family, member 5B 0.434524
CD79A CD79a molecule, immunoglobulin-associated alpha 0.432646
DCAF13 DDB1 and CUL4 associated factor 13 0.430393
FN1 fibronectin 1 0.430393
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.42664
ZSCAN10 zinc finger and SCAN domain containing 10 0.42664
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.42589
CRTAP cartilage associated protein 0.42589
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.424014
EMP1 epithelial membrane protein 1 0.42364
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.423265
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 0.421016
PRRC2A proline-rich coiled-coil 2A 0.418394
GHR growth hormone receptor 0.418019
KLK3 kallikrein-related peptidase 3 0.416521
JAG1 jagged 1 0.415024
CLCN7 chloride channel, voltage-sensitive 7 0.413901
IL20RA interleukin 20 receptor, alpha 0.412779
PRL prolactin 0.412031
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.411657
WASF2 WAS protein family, member 2 0.410161
LDLR low density lipoprotein receptor 0.407545
SCOC short coiled-coil protein 0.404557
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.404184
RNF185 ring finger protein 185 0.401945
CRH corticotropin releasing hormone 0.398962
SLMO2 slowmo homolog 2 (Drosophila) 0.397098
AXIN2 axin 2 0.393001
OSM oncostatin M 0.392257
PTS 6-pyruvoyltetrahydropterin synthase 0.391513
FAM9B family with sequence similarity 9, member B 0.389281
NF1 neurofibromin 1 0.388166
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 0.382223
POSTN periostin, osteoblast specific factor 0.382223
CARTPT CART prepropeptide 0.38111
CER1 cerberus 1, DAN family BMP antagonist 0.38111
FAM3C family with sequence similarity 3, member C 0.379997
PHEX phosphate regulating endopeptidase homolog, X-linked 0.377402
FST follistatin 0.372958
GGT1 gamma-glutamyltransferase 1 0.371847
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.371107
CST3 cystatin C 0.36741
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.366671
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 0.366301
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.365932
HOPX HOP homeobox 0.365562
FICD FIC domain containing 0.364824
STARD3NL STARD3 N-terminal like 0.36187
AHR aryl hydrocarbon receptor 0.36187
CSK c-src tyrosine kinase 0.361133
TPH1 tryptophan hydroxylase 1 0.35892
PLCL1 phospholipase C-like 1 0.357446
NOS3 nitric oxide synthase 3 (endothelial cell) 0.354499
CA8 carbonic anhydrase VIII 0.353395
PDE4A phosphodiesterase 4A, cAMP-specific 0.352659
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 0.349349
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 0.348246
NPS neuropeptide S 0.344941
TRIM25 tripartite motif containing 25 0.342006
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.340906
OXTR oxytocin receptor 0.340539
GHRH growth hormone releasing hormone 0.340173
OCSTAMP osteoclast stimulatory transmembrane protein 0.337975
DCDC5 doublecortin domain containing 5 0.33651
CDX2 caudal type homeobox 2 0.333218
WIF1 WNT inhibitory factor 1 0.333218
MX1 MX dynamin-like GTPase 1 0.332487
CALB1 calbindin 1, 28kDa 0.332121
CPED1 cadherin-like and PC-esterase domain containing 1 0.332121
IRAK3 interleukin-1 receptor-associated kinase 3 0.331756
OGN osteoglycin 0.331025
IHH indian hedgehog 0.328834
MMP1 matrix metallopeptidase 1 0.32774
IL7 interleukin 7 0.327375
MAPK3 mitogen-activated protein kinase 3 0.327375
SIRT2 sirtuin 2 0.325187
NRM nurim (nuclear envelope membrane protein) 0.322273
PLXNA2 plexin A2 0.321909
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.320817
CFD complement factor D (adipsin) 0.317909
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.317545
FAM131C family with sequence similarity 131, member C 0.316819
KREMEN1 kringle containing transmembrane protein 1 0.315366
SFRP4 secreted frizzled-related protein 4 0.314278
TMEM14A transmembrane protein 14A 0.312102
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 0.312102
SBDS Shwachman-Bodian-Diamond syndrome 0.311739
CBS cystathionine-beta-synthase 0.31029
CA5A carbonic anhydrase VA, mitochondrial 0.309566
WISP3 WNT1 inducible signaling pathway protein 3 0.308842
TGFB2 transforming growth factor, beta 2 0.305587
SMAD4 SMAD family member 4 0.30342
MSX2 msh homeobox 2 0.302698
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.302698
PLS3 plastin 3 0.302337
FTL ferritin, light polypeptide 0.301976
FTH1 ferritin, heavy polypeptide 1 0.301615
PPARA peroxisome proliferator-activated receptor alpha 0.298731
HHIPL2 HHIP-like 2 0.297651
ONECUT3 one cut homeobox 3 0.297291
TMED2 transmembrane emp24 domain trafficking protein 2 0.296931
MSTN myostatin 0.296571
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.292616
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.290462
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.289027
BAX BCL2-associated X protein 0.289027
UBE2K ubiquitin-conjugating enzyme E2K 0.286519
TXNRD2 thioredoxin reductase 2 0.286519
CAT catalase 0.285444
NUP205 nucleoporin 205kDa 0.284728
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.284371
COG2 component of oligomeric golgi complex 2 0.284013
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16 0.281153
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.280082
TREML2 triggering receptor expressed on myeloid cells-like 2 0.278654
DLK2 delta-like 2 homolog (Drosophila) 0.278654
SP6 Sp6 transcription factor 0.276514
LMNA lamin A/C 0.274376
UBA5 ubiquitin-like modifier activating enzyme 5 0.272241
ZFYVE1 zinc finger, FYVE domain containing 1 0.27153
IARS isoleucyl-tRNA synthetase 0.27153
MMP2 matrix metallopeptidase 2 0.27153
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.271174
TSPO translocator protein (18kDa) 0.271174
COL2A1 collagen, type II, alpha 1 0.270108
AKAP6 A kinase (PRKA) anchor protein 6 0.268687
DCHS2 dachsous cadherin-related 2 0.268332
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.26266
LTF lactotransferrin 0.261245
VEGFA vascular endothelial growth factor A 0.260538
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.259124
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.25877
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.258417
IGFBP4 insulin-like growth factor binding protein 4 0.258064
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.258064
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.257711
C1ORF61 chromosome 1 open reading frame 61 0.254888
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.253831
BMP3 bone morphogenetic protein 3 0.253127
GDF2 growth differentiation factor 2 0.24996
NIPSNAP3B nipsnap homolog 3B (C. elegans) 0.24996
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.248203
HEBP1 heme binding protein 1 0.247852
LAX1 lymphocyte transmembrane adaptor 1 0.247501
SOSTDC1 sclerostin domain containing 1 0.246799
P3H1 prolyl 3-hydroxylase 1 0.246448
ADCY2 adenylate cyclase 2 (brain) 0.245747
FAM120A family with sequence similarity 120A 0.245396
MATN2 matrilin 2 0.245396
ZMPSTE24 zinc metallopeptidase STE24 0.245046
SIRPA signal-regulatory protein alpha 0.244696
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.243995
QPCT glutaminyl-peptide cyclotransferase 0.243295
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.240148
DPYD dihydropyrimidine dehydrogenase 0.240148
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.239799
GATAD2B GATA zinc finger domain containing 2B 0.238752
CA10 carbonic anhydrase X 0.23666
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.236312
TYROBP TYRO protein tyrosine kinase binding protein 0.235616
CSF1 colony stimulating factor 1 (macrophage) 0.23492
CA1 carbonic anhydrase I 0.234573
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.228333
DVL2 dishevelled segment polarity protein 2 0.227642
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.225573
HYLS1 hydrolethalus syndrome 1 0.224196
PRDM11 PR domain containing 11 0.223509
ZNF516 zinc finger protein 516 0.223509
FLNB filamin B, beta 0.223509
PGR progesterone receptor 0.223509
GCG glucagon 0.222479
C10ORF88 chromosome 10 open reading frame 88 0.222136
NFYB nuclear transcription factor Y, beta 0.22145
ADGRV1 adhesion G protein-coupled receptor V1 0.220424
TAC1 tachykinin, precursor 1 0.220081
CABIN1 calcineurin binding protein 1 0.219057
GOLGA6A golgin A6 family, member A 0.218715
GOLGA6B golgin A6 family, member B 0.218715
EGFL8 EGF-like-domain, multiple 8 0.218374
PTK2B protein tyrosine kinase 2 beta 0.214297
CTSL cathepsin L 0.214297
TRAM2 translocation associated membrane protein 2 0.213959
PCDH8 protocadherin 8 0.213283
CTF1 cardiotrophin 1 0.212945
SEC24C SEC24 family member C 0.211261
COMP cartilage oligomeric matrix protein 0.208579
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 0.208579
MAB21L2 mab-21-like 2 (C. elegans) 0.208245
IRS2 insulin receptor substrate 2 0.205254
CD47 CD47 molecule 0.204593
PRKCZ protein kinase C, zeta 0.203933
SIRT5 sirtuin 5 0.203933
SIRT4 sirtuin 4 0.203275
FGF1 fibroblast growth factor 1 (acidic) 0.202946
CA3 carbonic anhydrase III 0.202946
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.20229
SQSTM1 sequestosome 1 0.200982
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.200656
ADM adrenomedullin 0.200006
BMP15 bone morphogenetic protein 15 0.199356
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.199033
MAP3K7CL MAP3K7 C-terminal like 0.197099
SIRT7 sirtuin 7 0.195501
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.194232
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.192971
FBXO15 F-box protein 15 0.192971
SHOX short stature homeobox 0.192657
CTSB cathepsin B 0.191719
GIMAP1 GTPase, IMAP family member 1 0.190786
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.190476
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.186811
TRH thyrotropin-releasing hormone 0.18651
IGFBP1 insulin-like growth factor binding protein 1 0.18651
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.18591
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.185313
FUCA1 fucosidase, alpha-L- 1, tissue 0.185016
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.184424
CNR2 cannabinoid receptor 2 (macrophage) 0.183835
NOVA2 neuro-oncological ventral antigen 2 0.182086
RETN resistin 0.181798
PROS1 protein S (alpha) 0.181798
MMP3 matrix metallopeptidase 3 0.181222
CA7 carbonic anhydrase VII 0.181222
GAB2 GRB2-associated binding protein 2 0.180084
DTNBP1 dystrobrevin binding protein 1 0.180084
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.179802
WNT4 wingless-type MMTV integration site family, member 4 0.17896
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.17896
MBIP MAP3K12 binding inhibitory protein 1 0.17896
CNOT3 CCR4-NOT transcription complex, subunit 3 0.178682
MITF microphthalmia-associated transcription factor 0.178682
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.178403
IRS1 insulin receptor substrate 1 0.178403
JUNB jun B proto-oncogene 0.177851
ERCC8 excision repair cross-complementation group 8 0.177851
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.177301
CA14 carbonic anhydrase XIV 0.176757
DUSP1 dual specificity phosphatase 1 0.175947
COL6A1 collagen, type VI, alpha 1 0.175679
FOXL1 forkhead box L1 0.174354
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.171785
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.170054
KMT2A lysine (K)-specific methyltransferase 2A 0.169812
MTL5 metallothionein-like 5, testis-specific (tesmin) 0.169812
S1PR2 sphingosine-1-phosphate receptor 2 0.169812
NRIP1 nuclear receptor interacting protein 1 0.169571
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.169571
ITGAV integrin, alpha V 0.16933
SIK1 salt-inducible kinase 1 0.16933
LEF1 lymphoid enhancer-binding factor 1 0.168381
PRIMA1 proline rich membrane anchor 1 0.167915
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.167682
ALOX5 arachidonate 5-lipoxygenase 0.167452
AKAP11 A kinase (PRKA) anchor protein 11 0.166544
ICAM1 intercellular adhesion molecule 1 0.166095
TRPS1 trichorhinophalangeal syndrome I 0.164786
TOB2 transducer of ERBB2, 2 0.164359
TGFB3 transforming growth factor, beta 3 0.163938
COPG1 coatomer protein complex, subunit gamma 1 0.163938
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.163729
RNF19B ring finger protein 19B 0.163729
HRAS Harvey rat sarcoma viral oncogene homolog 0.163729
ARHGAP1 Rho GTPase activating protein 1 0.163729
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.163523
ANKRD28 ankyrin repeat domain 28 0.163317
FABP3 fatty acid binding protein 3, muscle and heart 0.162707
C6ORF25 chromosome 6 open reading frame 25 0.162306
PCNA proliferating cell nuclear antigen 0.162109
ACVR2A activin A receptor, type IIA 0.161523
TWF1 twinfilin actin binding protein 1 0.161139
SIRT6 sirtuin 6 0.160948
BCL2L1 BCL2-like 1 0.160761
IFNE interferon, epsilon 0.160761
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.160574
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.160203
TTR transthyretin 0.159838
CCDC34 coiled-coil domain containing 34 0.159658
TSPAN3 tetraspanin 3 0.159658
RAB5C RAB5C, member RAS oncogene family 0.15948
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 0.159302
CAPNS1 calpain, small subunit 1 0.158097
IL20RB interleukin 20 receptor beta 0.158097
CA13 carbonic anhydrase XIII 0.157929
ITPK1 inositol-tetrakisphosphate 1-kinase 0.157602
NIPBL Nipped-B homolog (Drosophila) 0.144068
NPSR1 neuropeptide S receptor 1 0.142748
APEH acylaminoacyl-peptide hydrolase 0.140197
MCM3 minichromosome maintenance complex component 3 0.138734
PDHX pyruvate dehydrogenase complex, component X 0.135068
RHAG Rh-associated glycoprotein 0.132388
EPO erythropoietin 0.131889
GNAS GNAS complex locus 0.131159
HPN hepsin 0.129797
MCM2 minichromosome maintenance complex component 2 0.126926
RPS19BP1 ribosomal protein S19 binding protein 1 0.126861
RBMS3 RNA binding motif, single stranded interacting protein 3 0.126861
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.126829
F3 coagulation factor III (thromboplastin, tissue factor) 0.126797
CCND1 cyclin D1 0.126731
LCK LCK proto-oncogene, Src family tyrosine kinase 0.126431