biliary tract abnormality Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0001080
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Genes

139 genes associated with the biliary tract abnormality phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
MST1 macrophage stimulating 1 1.81736
GPR35 G protein-coupled receptor 35 1.32793
TCF4 transcription factor 4 1.19958
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.18535
IL2RA interleukin 2 receptor, alpha 1.05454
GAS7 growth arrest-specific 7 1.05454
HDAC7 histone deacetylase 7 1.04365
PLXNA4 plexin A4 1.02289
PTPRU protein tyrosine phosphatase, receptor type, U 1.01499
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.99698
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 0.98717
BSPRY B-box and SPRY domain containing 0.977911
KIRREL3 kin of IRRE like 3 (Drosophila) 0.952642
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.855449
TENM4 teneurin transmembrane protein 4 0.7965
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.766963
IL12RB2 interleukin 12 receptor, beta 2 0.720953
STK35 serine/threonine kinase 35 0.681679
ACAD9 acyl-CoA dehydrogenase family, member 9 0.651923
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.581861
TNPO3 transportin 3 0.575657
AJAP1 adherens junctions associated protein 1 0.562717
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.562717
MTUS2 microtubule associated tumor suppressor candidate 2 0.549174
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.539082
ZPR1 ZPR1 zinc finger 0.535185
GLDC glycine dehydrogenase (decarboxylating) 0.531556
LY9 lymphocyte antigen 9 0.528162
THSD7A thrombospondin, type I, domain containing 7A 0.525058
TSC1 tuberous sclerosis 1 0.519375
PEX14 peroxisomal biogenesis factor 14 0.519375
KDM4C lysine (K)-specific demethylase 4C 0.519375
KLHL29 kelch-like family member 29 0.516758
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 0.514254
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.509391
AGBL4 ATP/GTP binding protein-like 4 0.509391
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 0.507122
CNTN4 contactin 4 0.507122
LYZL2 lysozyme-like 2 0.50495
GPC6 glypican 6 0.50495
ONECUT1 one cut homeobox 1 0.50086
AK8 adenylate kinase 8 0.50086
GRID1 glutamate receptor, ionotropic, delta 1 0.496801
ASTN2 astrotactin 2 0.489511
TTBK1 tau tubulin kinase 1 0.486163
CEP85 centrosomal protein 85kDa 0.484434
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.478587
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.478004
SDCCAG8 serologically defined colon cancer antigen 8 0.470822
LMX1B LIM homeobox transcription factor 1, beta 0.469373
LIPK lipase, family member K 0.467959
ELL elongation factor RNA polymerase II 0.466578
CRTAC1 cartilage acidic protein 1 0.46012
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.45891
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.456563
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.454274
CSMD1 CUB and Sushi multiple domains 1 0.449892
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.449892
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 0.446935
LPPR1 lipid phosphate phosphatase-related protein type 1 0.443881
FBXL13 F-box and leucine-rich repeat protein 13 0.43784
HIP1 huntingtin interacting protein 1 0.437102
FGF14 fibroblast growth factor 14 0.436375
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.434255
CSMD2 CUB and Sushi multiple domains 2 0.43289
ADAM17 ADAM metallopeptidase domain 17 0.431561
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 0.427775
RPL3 ribosomal protein L3 0.423224
CLEC16A C-type lectin domain family 16, member A 0.41534
EXOC3L4 exocyst complex component 3-like 4 0.414164
RAD51B RAD51 paralog B 0.407397
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.406102
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.405929
C6ORF10 chromosome 6 open reading frame 10 0.401355
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 0.398566
ARHGAP31 Rho GTPase activating protein 31 0.398408
TMEM39A transmembrane protein 39A 0.397881
IL7R interleukin 7 receptor 0.396577
WDR70 WD repeat domain 70 0.394745
LOC100506272 uncharacterized LOC100506272 0.394058
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.386983
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.386983
DENND1B DENN/MADD domain containing 1B 0.386766
PRDM16 PR domain containing 16 0.375786
PLCL2 phospholipase C-like 2 0.372031
MED1 mediator complex subunit 1 0.371131
PRICKLE1 prickle homolog 1 (Drosophila) 0.368069
COL17A1 collagen, type XVII, alpha 1 0.367617
ELMO1 engulfment and cell motility 1 0.367568
DCC DCC netrin 1 receptor 0.36724
TP63 tumor protein p63 0.366898
CDK12 cyclin-dependent kinase 12 0.36088
SDK1 sidekick cell adhesion molecule 1 0.360757
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.356022
FBXL20 F-box and leucine-rich repeat protein 20 0.355375
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.354639
PAX3 paired box 3 0.352352
GRIK1 glutamate receptor, ionotropic, kainate 1 0.351763
CNTN5 contactin 5 0.351651
HPCAL1 hippocalcin-like 1 0.350729
GLI3 GLI family zinc finger 3 0.350713
MANBA mannosidase, beta A, lysosomal 0.350043
LY86-AS1 LY86 antisense RNA 1 0.34716
STAT4 signal transducer and activator of transcription 4 0.34437
CCDC88B coiled-coil domain containing 88B 0.343544
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 0.342918
LBH limb bud and heart development 0.339314
TMEM117 transmembrane protein 117 0.338944
MAMDC2 MAM domain containing 2 0.336385
ITPK1 inositol-tetrakisphosphate 1-kinase 0.336121
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.334459
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.33428
LMF1 lipase maturation factor 1 0.32961
C5ORF30 chromosome 5 open reading frame 30 0.328641
MAPT microtubule-associated protein tau 0.328497
PCBP3 poly(rC) binding protein 3 0.328093
KIAA0825 KIAA0825 0.326976
COLEC12 collectin sub-family member 12 0.326923
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.323989
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 0.322331
VWC2L von Willebrand factor C domain containing protein 2-like 0.320794
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.314887
NLRP5 NLR family, pyrin domain containing 5 0.313165
PSD3 pleckstrin and Sec7 domain containing 3 0.312165
ATP10B ATPase, class V, type 10B 0.312112
PSORS1C1 psoriasis susceptibility 1 candidate 1 0.309953
ADD3 adducin 3 (gamma) 0.309035
TDRD5 tudor domain containing 5 0.304211
SLC39A11 solute carrier family 39, member 11 0.302592
PRKCA protein kinase C, alpha 0.298856
RORA RAR-related orphan receptor A 0.2954
PRKCE protein kinase C, epsilon 0.2954
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.295116
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.294181
C2ORF66 chromosome 2 open reading frame 66 0.292395
PGAP1 post-GPI attachment to proteins 1 0.292395
C2ORF54 chromosome 2 open reading frame 54 0.279176
TGFBR1 transforming growth factor, beta receptor 1 0.254299
DSCAML1 Down syndrome cell adhesion molecule like 1 0.253625