betulin-3513 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the betulin-3513 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AFAP1 actin filament associated protein 1
ALDOB aldolase B, fructose-bisphosphate
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATN1 atrophin 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF54 chromosome 1 open reading frame 54
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CATSPERB catsper channel auxiliary subunit beta
CD70 CD70 molecule
CDC14A cell division cycle 14A
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CPQ carboxypeptidase Q
CRAT carnitine O-acetyltransferase
CTBP2 C-terminal binding protein 2
CYLD cylindromatosis (turban tumor syndrome)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDIT3 DNA-damage-inducible transcript 3
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DTNA dystrobrevin, alpha
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDA ectodysplasin A
EIF3F eukaryotic translation initiation factor 3, subunit F
EML2 echinoderm microtubule associated protein like 2
ENO3 enolase 3 (beta, muscle)
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ETV6 ets variant 6
FADS2 fatty acid desaturase 2
FGF2 fibroblast growth factor 2 (basic)
FSTL1 follistatin-like 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GOSR2 golgi SNAP receptor complex member 2
GPR137 G protein-coupled receptor 137
GSPT1 G1 to S phase transition 1
HDAC7 histone deacetylase 7
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ICA1 islet cell autoantigen 1, 69kDa
IFT27 intraflagellar transport 27
IL11 interleukin 11
IPO8 importin 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
MAOA monoamine oxidase A
MARS methionyl-tRNA synthetase
MST1 macrophage stimulating 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MUC1 mucin 1, cell surface associated
MZF1 myeloid zinc finger 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NRN1 neuritin 1
NXPH3 neurexophilin 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVOL1 ovo-like zinc finger 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGAP3 post-GPI attachment to proteins 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLXNB3 plexin B3
PMFBP1 polyamine modulated factor 1 binding protein 1
POU1F1 POU class 1 homeobox 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSD3 pleckstrin and Sec7 domain containing 3
PTPRM protein tyrosine phosphatase, receptor type, M
PVR poliovirus receptor
PXN paxillin
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RPS3A ribosomal protein S3A
SAMD9 sterile alpha motif domain containing 9
SDC2 syndecan 2
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SIX1 SIX homeobox 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SOX15 SRY (sex determining region Y)-box 15
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STRN striatin, calmodulin binding protein
SWAP70 SWAP switching B-cell complex 70kDa subunit
TNC tenascin C
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TPSAB1 tryptase alpha/beta 1
TRIM15 tripartite motif containing 15
TYRP1 tyrosinase-related protein 1
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB48 zinc finger and BTB domain containing 48
ZER1 zyg-11 related, cell cycle regulator
ZNF329 zinc finger protein 329

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
AMDHD2 amidohydrolase domain containing 2
AMT aminomethyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASPHD1 aspartate beta-hydroxylase domain containing 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHCC1 BAH domain and coiled-coil containing 1
BEGAIN brain-enriched guanylate kinase-associated
BRPF1 bromodomain and PHD finger containing, 1
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF95 chromosome 10 open reading frame 95
C22ORF46 chromosome 22 open reading frame 46
C2ORF27A chromosome 2 open reading frame 27A
C9ORF3 chromosome 9 open reading frame 3
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
DVL1 dishevelled segment polarity protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF5A2 eukaryotic translation initiation factor 5A2
EN2 engrailed homeobox 2
FAM118A family with sequence similarity 118, member A
FAM46C family with sequence similarity 46, member C
FILIP1L filamin A interacting protein 1-like
FLNC filamin C, gamma
FOXN2 forkhead box N2
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
H2AFY2 H2A histone family, member Y2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-DMA major histocompatibility complex, class II, DM alpha
INPP1 inositol polyphosphate-1-phosphatase
KCTD20 potassium channel tetramerization domain containing 20
LIME1 Lck interacting transmembrane adaptor 1
LRP5L low density lipoprotein receptor-related protein 5-like
LRP6 low density lipoprotein receptor-related protein 6
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC49 leucine rich repeat containing 49
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
MAGEA6 melanoma antigen family A6
MMP2 matrix metallopeptidase 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NCALD neurocalcin delta
NLRX1 NLR family member X1
NT5DC3 5'-nucleotidase domain containing 3
PALM paralemmin
PCDHA9 protocadherin alpha 9
PCDHB3 protocadherin beta 3
PCDHB8 protocadherin beta 8
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PRODH proline dehydrogenase (oxidase) 1
QSER1 glutamine and serine rich 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RASL11B RAS-like, family 11, member B
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
RUSC2 RUN and SH3 domain containing 2
SCARA3 scavenger receptor class A, member 3
SCD5 stearoyl-CoA desaturase 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SCRN3 secernin 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SKI SKI proto-oncogene
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STBD1 starch binding domain 1
STXBP2 syntaxin binding protein 2
TCHH trichohyalin
TCP10 t-complex 10
TCTN2 tectonic family member 2
TGFB3 transforming growth factor, beta 3
TMEM121 transmembrane protein 121
TMLHE trimethyllysine hydroxylase, epsilon
TRIM66 tripartite motif containing 66
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UPK3B uroplakin 3B
VEGFB vascular endothelial growth factor B
WDR25 WD repeat domain 25
WLS wntless Wnt ligand secretion mediator
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF205 zinc finger protein 205
ZNF37BP zinc finger protein 37B, pseudogene