benzethonium chloride-2508 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the benzethonium chloride-2508 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AHNAK AHNAK nucleoprotein
ALDOB aldolase B, fructose-bisphosphate
ANK2 ankyrin 2, neuronal
ARHGAP35 Rho GTPase activating protein 35
ARID4B AT rich interactive domain 4B (RBP1-like)
AURKA aurora kinase A
BLZF1 basic leucine zipper nuclear factor 1
C8A complement component 8, alpha polypeptide
CCDC71 coiled-coil domain containing 71
CD22 CD22 molecule
CD47 CD47 molecule
CD84 CD84 molecule
CDC14A cell division cycle 14A
CDC25C cell division cycle 25C
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP250 centrosomal protein 250kDa
CLEC1B C-type lectin domain family 1, member B
COL1A2 collagen, type I, alpha 2
COL9A3 collagen, type IX, alpha 3
CTNND1 catenin (cadherin-associated protein), delta 1
CYHR1 cysteine/histidine-rich 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DIAPH2 diaphanous-related formin 2
DIAPH2-AS1 DIAPH2 antisense RNA 1
DPEP2 dipeptidase 2
EIF1 eukaryotic translation initiation factor 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EVI5 ecotropic viral integration site 5
FAM134B family with sequence similarity 134, member B
FHL1 four and a half LIM domains 1
FOXO4 forkhead box O4
GID4 GID complex subunit 4
GLE1 GLE1 RNA export mediator
GMPR guanosine monophosphate reductase
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AC histone cluster 1, H2ac
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HOXA6 homeobox A6
HOXA9 homeobox A9
HPD 4-hydroxyphenylpyruvate dioxygenase
IL1R1 interleukin 1 receptor, type I
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INS insulin
IQSEC1 IQ motif and Sec7 domain 1
IZUMO4 IZUMO family member 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA1109 KIAA1109
KLF2 Kruppel-like factor 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LINC00597 long intergenic non-protein coding RNA 597
LPAR1 lysophosphatidic acid receptor 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBD2 methyl-CpG binding domain protein 2
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBNL2 muscleblind-like splicing regulator 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MKL2 MKL/myocardin-like 2
MPPE1 metallophosphoesterase 1
MSRB2 methionine sulfoxide reductase B2
MT1F metallothionein 1F
MXD3 MAX dimerization protein 3
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NRG2 neuregulin 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE4B phosphodiesterase 4B, cAMP-specific
PLA2G3 phospholipase A2, group III
PLA2G5 phospholipase A2, group V
POFUT1 protein O-fucosyltransferase 1
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTBP3 polypyrimidine tract binding protein 3
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RPL10L ribosomal protein L10-like
RRBP1 ribosome binding protein 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SKIL SKI-like proto-oncogene
SLC12A8 solute carrier family 12, member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNX29P2 sorting nexin 29 pseudogene 2
TADA3 transcriptional adaptor 3
TAPBP TAP binding protein (tapasin)
TAS2R1 taste receptor, type 2, member 1
TAT tyrosine aminotransferase
TBC1D2 TBC1 domain family, member 2
TGFB1 transforming growth factor, beta 1
TLK1 tousled-like kinase 1
USP6NL USP6 N-terminal like
ZER1 zyg-11 related, cell cycle regulator
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADM adrenomedullin
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARG1 arginase 1
ASAP1-IT1 ASAP1 intronic transcript 1
ATF3 activating transcription factor 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BSPRY B-box and SPRY domain containing
C10ORF2 chromosome 10 open reading frame 2
C1ORF21 chromosome 1 open reading frame 21
C1RL complement component 1, r subcomponent-like
C3 complement component 3
C5 complement component 5
CABP2 calcium binding protein 2
CCDC176 coiled-coil domain containing 176
CCDC88C coiled-coil domain containing 88C
CCL20 chemokine (C-C motif) ligand 20
CD300C CD300c molecule
CD69 CD69 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDHR2 cadherin-related family member 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDR2L cerebellar degeneration-related protein 2-like
CFP complement factor properdin
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDN dendrin
DHRS11 dehydrogenase/reductase (SDR family) member 11
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
DUSP8 dual specificity phosphatase 8
EFNA3 ephrin-A3
ENDOG endonuclease G
ENO2 enolase 2 (gamma, neuronal)
FBXL7 F-box and leucine-rich repeat protein 7
GATAD2A GATA zinc finger domain containing 2A
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNL1 guanine nucleotide binding protein-like 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCAR3 hydroxycarboxylic acid receptor 3
HILPDA hypoxia inducible lipid droplet-associated
HYAL3 hyaluronoglucosaminidase 3
INCENP inner centromere protein antigens 135/155kDa
IRF7 interferon regulatory factor 7
ITGA10 integrin, alpha 10
JMJD4 jumonji domain containing 4
JUN jun proto-oncogene
KIF17 kinesin family member 17
KIFC1 kinesin family member C1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MPI mannose phosphate isomerase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MTSS1L metastasis suppressor 1-like
MYO1E myosin IE
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
NPM3 nucleophosmin/nucleoplasmin 3
NTSR1 neurotensin receptor 1 (high affinity)
OXTR oxytocin receptor
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PADI2 peptidyl arginine deiminase, type II
PHACTR1 phosphatase and actin regulator 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PODNL1 podocan-like 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB13 RAB13, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS16 regulator of G-protein signaling 16
RLF rearranged L-myc fusion
RNF122 ring finger protein 122
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SIL1 SIL1 nucleotide exchange factor
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOX12 SRY (sex determining region Y)-box 12
SPRYD7 SPRY domain containing 7
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAS2R10 taste receptor, type 2, member 10
THBS3 thrombospondin 3
TMEM45A transmembrane protein 45A
TREM1 triggering receptor expressed on myeloid cells 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
TXLNG taxilin gamma
VEGFC vascular endothelial growth factor C
ZNF37BP zinc finger protein 37B, pseudogene
ZNF395 zinc finger protein 395
ZNF428 zinc finger protein 428