benserazide-5322 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the benserazide-5322 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAGAB alpha- and gamma-adaptin binding protein
ADAM22 ADAM metallopeptidase domain 22
ADRA1D adrenoceptor alpha 1D
ADTRP androgen-dependent TFPI-regulating protein
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKIP1 A kinase (PRKA) interacting protein 1
AMH anti-Mullerian hormone
AMPH amphiphysin
ANKMY1 ankyrin repeat and MYND domain containing 1
APOC1 apolipoprotein C-I
APOL2 apolipoprotein L, 2
ARMC4 armadillo repeat containing 4
C7ORF43 chromosome 7 open reading frame 43
CABIN1 calcineurin binding protein 1
CCDC71 coiled-coil domain containing 71
CCHCR1 coiled-coil alpha-helical rod protein 1
CEP162 centrosomal protein 162kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIDEB cell death-inducing DFFA-like effector b
CTBS chitobiase, di-N-acetyl-
DLX4 distal-less homeobox 4
DSCAM Down syndrome cell adhesion molecule
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EML3 echinoderm microtubule associated protein like 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC7 exocyst complex component 7
EZR ezrin
FAM184A family with sequence similarity 184, member A
FUS FUS RNA binding protein
GADD45G growth arrest and DNA-damage-inducible, gamma
GJB3 gap junction protein, beta 3, 31kDa
GLP1R glucagon-like peptide 1 receptor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRSF1 G-rich RNA sequence binding factor 1
HSPA1L heat shock 70kDa protein 1-like
JRK Jrk homolog (mouse)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMP1 lysosomal-associated membrane protein 1
LARP7 La ribonucleoprotein domain family, member 7
LHX1 LIM homeobox 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC647070 uncharacterized LOC647070
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTB4R leukotriene B4 receptor
LZTR1 leucine-zipper-like transcription regulator 1
MAGOH2P mago-nashi homolog 2, pseudogene
MAP4 microtubule-associated protein 4
MAPK7 mitogen-activated protein kinase 7
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTA1 metastasis associated 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NPIPB15 nuclear pore complex interacting protein family, member B15
NR2F6 nuclear receptor subfamily 2, group F, member 6
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI1 peptidyl arginine deiminase, type I
PARK2 parkin RBR E3 ubiquitin protein ligase
PARVB parvin, beta
PAWR PRKC, apoptosis, WT1, regulator
PCDH12 protocadherin 12
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRKD3 protein kinase D3
RAB3A RAB3A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RPL26 ribosomal protein L26
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD8 SET domain containing (lysine methyltransferase) 8
SFTPB surfactant protein B
SOGA1 suppressor of glucose, autophagy associated 1
SPDEF SAM pointed domain containing ETS transcription factor
SRSF7 serine/arginine-rich splicing factor 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TAOK2 TAO kinase 2
TBC1D2B TBC1 domain family, member 2B
TCF3 transcription factor 3
TMEM212 transmembrane protein 212
TMEM259 transmembrane protein 259
TMOD1 tropomodulin 1
TMPRSS2 transmembrane protease, serine 2
TRAK1 trafficking protein, kinesin binding 1
VAV1 vav 1 guanine nucleotide exchange factor
ZFP36L2 ZFP36 ring finger protein-like 2
ZMAT5 zinc finger, matrin-type 5
ZNF205 zinc finger protein 205
ZNF318 zinc finger protein 318
ZNF552 zinc finger protein 552
ZNF710 zinc finger protein 710
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDOC aldolase C, fructose-bisphosphate
ANKRD28 ankyrin repeat domain 28
ASB7 ankyrin repeat and SOCS box containing 7
AXIN1 axin 1
BAX BCL2-associated X protein
C14ORF132 chromosome 14 open reading frame 132
C4ORF19 chromosome 4 open reading frame 19
CADPS2 Ca++-dependent secretion activator 2
CLASP1 cytoplasmic linker associated protein 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DNA2 DNA replication helicase/nuclease 2
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EFHD1 EF-hand domain family, member D1
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
ERCC5 excision repair cross-complementation group 5
ERCC8 excision repair cross-complementation group 8
ERO1L ERO1-like (S. cerevisiae)
FGGY FGGY carbohydrate kinase domain containing
FKBP14 FK506 binding protein 14, 22 kDa
FOXJ2 forkhead box J2
GAR1 GAR1 ribonucleoprotein
GATAD2A GATA zinc finger domain containing 2A
GCHFR GTP cyclohydrolase I feedback regulator
GLB1L2 galactosidase, beta 1-like 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GOLGA8B golgin A8 family, member B
H1F0 H1 histone family, member 0
HIRA histone cell cycle regulator
IFI6 interferon, alpha-inducible protein 6
IFT20 intraflagellar transport 20
IRF6 interferon regulatory factor 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0430 KIAA0430
KLHL12 kelch-like family member 12
KRI1 KRI1 homolog (S. cerevisiae)
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGOHB mago-nashi homolog B (Drosophila)
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MARC1 mitochondrial amidoxime reducing component 1
MBIP MAP3K12 binding inhibitory protein 1
MBTD1 mbt domain containing 1
MDN1 MDN1, midasin homolog (yeast)
MECR mitochondrial trans-2-enoyl-CoA reductase
MED15 mediator complex subunit 15
METTL16 methyltransferase like 16
MKNK2 MAP kinase interacting serine/threonine kinase 2
MYO1D myosin ID
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPY1R neuropeptide Y receptor Y1
NUBPL nucleotide binding protein-like
NXN nucleoredoxin
ORAI3 ORAI calcium release-activated calcium modulator 3
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POT1 protection of telomeres 1
PRAF2 PRA1 domain family, member 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PROS1 protein S (alpha)
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTCD3 pentatricopeptide repeat domain 3
PTOV1 prostate tumor overexpressed 1
RAB23 RAB23, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RLF rearranged L-myc fusion
RNF187 ring finger protein 187
RSAD1 radical S-adenosyl methionine domain containing 1
SFT2D2 SFT2 domain containing 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SHPK sedoheptulokinase
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SQRDL sulfide quinone reductase-like (yeast)
STBD1 starch binding domain 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TLN1 talin 1
TRNAU1AP tRNA selenocysteine 1 associated protein 1
USP6NL USP6 N-terminal like
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WWC3 WWC family member 3
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF180 zinc finger protein 180
ZNF184 zinc finger protein 184
ZNF394 zinc finger protein 394