azlocillin-6262 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the azlocillin-6262 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAM22 ADAM metallopeptidase domain 22
AMPD1 adenosine monophosphate deaminase 1
ANGEL2 angel homolog 2 (Drosophila)
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB1 ankyrin repeat and SOCS box containing 1
ATXN2L ataxin 2-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
C10ORF95 chromosome 10 open reading frame 95
CALML3 calmodulin-like 3
CCL27 chemokine (C-C motif) ligand 27
CDRT1 CMT1A duplicated region transcript 1
CDY1 chromodomain protein, Y-linked, 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLDN17 claudin 17
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL14A1 collagen, type XIV, alpha 1
CRYAB crystallin, alpha B
DCT dopachrome tautomerase
DIEXF digestive organ expansion factor homolog (zebrafish)
DMC1 DNA meiotic recombinase 1
DMP1 dentin matrix acidic phosphoprotein 1
EGFR epidermal growth factor receptor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EXD3 exonuclease 3'-5' domain containing 3
FABP3 fatty acid binding protein 3, muscle and heart
FBXO22 F-box protein 22
FXYD2 FXYD domain containing ion transport regulator 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR21 G protein-coupled receptor 21
GSTA4 glutathione S-transferase alpha 4
ICAM1 intercellular adhesion molecule 1
IL36G interleukin 36, gamma
JMJD4 jumonji domain containing 4
KLF6 Kruppel-like factor 6
KRT16 keratin 16, type I
LGALS2 lectin, galactoside-binding, soluble, 2
LOC730101 uncharacterized LOC730101
LPIN2 lipin 2
MBD2 methyl-CpG binding domain protein 2
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MID1 midline 1
MYOZ1 myozenin 1
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NIPAL2 NIPA-like domain containing 2
NOP14-AS1 NOP14 antisense RNA 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAX5 paired box 5
PCNX pecanex homolog (Drosophila)
PDCD2 programmed cell death 2
PDGFB platelet-derived growth factor beta polypeptide
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHTF2 putative homeodomain transcription factor 2
PLK4 polo-like kinase 4
PLSCR3 phospholipid scramblase 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTCH1 patched 1
PTGES prostaglandin E synthase
PTGIS prostaglandin I2 (prostacyclin) synthase
QKI QKI, KH domain containing, RNA binding
RAB3D RAB3D, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RANBP1 RAN binding protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPL13 ribosomal protein L13
RRBP1 ribosome binding protein 1
SCAPER S-phase cyclin A-associated protein in the ER
SFXN3 sideroflexin 3
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOGA1 suppressor of glucose, autophagy associated 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPPL2B signal peptide peptidase like 2B
SRCAP Snf2-related CREBBP activator protein
SRP72 signal recognition particle 72kDa
SRRT serrate, RNA effector molecule
STAG3 stromal antigen 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAT tyrosine aminotransferase
TIGD6 tigger transposable element derived 6
TMEM97 transmembrane protein 97
TRPM2 transient receptor potential cation channel, subfamily M, member 2
VAMP5 vesicle-associated membrane protein 5
VAX2 ventral anterior homeobox 2
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YIPF2 Yip1 domain family, member 2
ZBTB48 zinc finger and BTB domain containing 48
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AKTIP AKT interacting protein
ANKRD28 ankyrin repeat domain 28
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARHGAP10 Rho GTPase activating protein 10
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARRB2 arrestin, beta 2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C10ORF88 chromosome 10 open reading frame 88
CAPN15 calpain 15
CCDC88C coiled-coil domain containing 88C
CDR2L cerebellar degeneration-related protein 2-like
CHIC2 cysteine-rich hydrophobic domain 2
CLASRP CLK4-associating serine/arginine rich protein
CLK2 CDC-like kinase 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COBL cordon-bleu WH2 repeat protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DENND1A DENN/MADD domain containing 1A
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNMBP dynamin binding protein
DUSP5 dual specificity phosphatase 5
ECHDC2 enoyl CoA hydratase domain containing 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EIF5A2 eukaryotic translation initiation factor 5A2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155B family with sequence similarity 155, member B
FAM53B family with sequence similarity 53, member B
FANCF Fanconi anemia, complementation group F
FBXO5 F-box protein 5
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FOCAD focadhesin
FPGS folylpolyglutamate synthase
GADD45G growth arrest and DNA-damage-inducible, gamma
GOLGA8B golgin A8 family, member B
H2AFY2 H2A histone family, member Y2
HHLA3 HERV-H LTR-associating 3
HIRA histone cell cycle regulator
HOOK1 hook microtubule-tethering protein 1
HOXC11 homeobox C11
IMPACT impact RWD domain protein
KIAA0513 KIAA0513
KIAA0753 KIAA0753
KIAA0894 KIAA0894 protein
KIAA0895 KIAA0895
LAMA3 laminin, alpha 3
LINC00339 long intergenic non-protein coding RNA 339
MIS12 MIS12 kinetochore complex component
NCAM2 neural cell adhesion molecule 2
NFS1 NFS1 cysteine desulfurase
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OXTR oxytocin receptor
PARD6A par-6 family cell polarity regulator alpha
PEX12 peroxisomal biogenesis factor 12
PHACTR4 phosphatase and actin regulator 4
PNKP polynucleotide kinase 3'-phosphatase
POLH polymerase (DNA directed), eta
POMZP3 POM121 and ZP3 fusion
PRR3 proline rich 3
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAD54L RAD54-like (S. cerevisiae)
RBL1 retinoblastoma-like 1
RCOR3 REST corepressor 3
REPS2 RALBP1 associated Eps domain containing 2
REV1 REV1, polymerase (DNA directed)
RPL23AP7 ribosomal protein L23a pseudogene 7
SCML1 sex comb on midleg-like 1 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A40 solute carrier family 25, member 40
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STK16 serine/threonine kinase 16
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTA T-cell leukemia translocation altered
TGFBI transforming growth factor, beta-induced, 68kDa
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TPST1 tyrosylprotein sulfotransferase 1
TSPAN14 tetraspanin 14
TXLNA taxilin alpha
UBE2S ubiquitin-conjugating enzyme E2S
VAV1 vav 1 guanine nucleotide exchange factor
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF165 zinc finger protein 165
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF668 zinc finger protein 668
ZNHIT2 zinc finger, HIT-type containing 2