azlocillin-3468 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the azlocillin-3468 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADCK4 aarF domain containing kinase 4
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMT aminomethyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARL4C ADP-ribosylation factor-like 4C
ARR3 arrestin 3, retinal (X-arrestin)
BAX BCL2-associated X protein
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C1QTNF3 C1q and tumor necrosis factor related protein 3
CCDC186 coiled-coil domain containing 186
CD82 CD82 molecule
CDC42 cell division cycle 42
CDH8 cadherin 8, type 2
CEP152 centrosomal protein 152kDa
CEP250 centrosomal protein 250kDa
CLCF1 cardiotrophin-like cytokine factor 1
COL5A1 collagen, type V, alpha 1
COL7A1 collagen, type VII, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
DMXL2 Dmx-like 2
DOK4 docking protein 4
E2F4 E2F transcription factor 4, p107/p130-binding
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPN2 epsin 2
EPS8L1 EPS8-like 1
ETAA1 Ewing tumor-associated antigen 1
FAM184A family with sequence similarity 184, member A
FHL1 four and a half LIM domains 1
FLCN folliculin
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GK3P glycerol kinase 3 pseudogene
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPATCH2L G patch domain containing 2-like
GYG2 glycogenin 2
HFE hemochromatosis
HIST1H4A histone cluster 1, H4a
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KLHL35 kelch-like family member 35
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRBOX4 KRAB box domain containing 4
LTBP2 latent transforming growth factor beta binding protein 2
MAP3K6 mitogen-activated protein kinase kinase kinase 6
METTL7A methyltransferase like 7A
MYOF myoferlin
PAX5 paired box 5
PCDHB13 protocadherin beta 13
PCSK6 proprotein convertase subtilisin/kexin type 6
PHF20 PHD finger protein 20
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POFUT1 protein O-fucosyltransferase 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RANBP3 RAN binding protein 3
RASAL2 RAS protein activator like 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RER1 retention in endoplasmic reticulum sorting receptor 1
RFXAP regulatory factor X-associated protein
RRAGD Ras-related GTP binding D
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOX12 SRY (sex determining region Y)-box 12
SOX9 SRY (sex determining region Y)-box 9
SP100 SP100 nuclear antigen
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STK38L serine/threonine kinase 38 like
STON1 stonin 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFE3 transcription factor binding to IGHM enhancer 3
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TRIM21 tripartite motif containing 21
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR55 WD repeat domain 55
WFDC2 WAP four-disulfide core domain 2
WNK1 WNK lysine deficient protein kinase 1
YY1 YY1 transcription factor
ZFP36L2 ZFP36 ring finger protein-like 2
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACTL8 actin-like 8
ADM adrenomedullin
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARMC6 armadillo repeat containing 6
ATAD5 ATPase family, AAA domain containing 5
BAG4 BCL2-associated athanogene 4
BCAS1 breast carcinoma amplified sequence 1
C11ORF80 chromosome 11 open reading frame 80
CAMKMT calmodulin-lysine N-methyltransferase
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCDC69 coiled-coil domain containing 69
CDK20 cyclin-dependent kinase 20
CEP170B centrosomal protein 170B
CHML choroideremia-like (Rab escort protein 2)
CISH cytokine inducible SH2-containing protein
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CPTP ceramide-1-phosphate transfer protein
DGKE diacylglycerol kinase, epsilon 64kDa
FAM131A family with sequence similarity 131, member A
FAM50B family with sequence similarity 50, member B
FBRS fibrosin
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP2 GTP binding protein 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H3B histone cluster 1, H3b
HTRA1 HtrA serine peptidase 1
IDI2-AS1 IDI2 antisense RNA 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INCENP inner centromere protein antigens 135/155kDa
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIF13B kinesin family member 13B
LMCD1 LIM and cysteine-rich domains 1
LMNB2 lamin B2
LPAR4 lysophosphatidic acid receptor 4
LY6D lymphocyte antigen 6 complex, locus D
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTD1 mbt domain containing 1
MCOLN1 mucolipin 1
MICALL2 MICAL-like 2
MIIP migration and invasion inhibitory protein
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MTHFSD methenyltetrahydrofolate synthetase domain containing
MVD mevalonate (diphospho) decarboxylase
NBEAL2 neurobeachin-like 2
NCSTN nicastrin
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NT5E 5'-nucleotidase, ecto (CD73)
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE8B phosphodiesterase 8B
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRR14L proline rich 14-like
PTPRU protein tyrosine phosphatase, receptor type, U
RAB3D RAB3D, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF170 ring finger protein 170
RPH3AL rabphilin 3A-like (without C2 domains)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLC46A3 solute carrier family 46, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUSD4 sushi domain containing 4
TAGLN transgelin
TCTN2 tectonic family member 2
TLN1 talin 1
TMEM62 transmembrane protein 62
TRIM66 tripartite motif containing 66
TUBG2 tubulin, gamma 2
USP27X ubiquitin specific peptidase 27, X-linked
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H3 zinc finger CCCH-type containing 3
ZNF532 zinc finger protein 532
ZNF668 zinc finger protein 668
ZNF747 zinc finger protein 747
ZSCAN26 zinc finger and SCAN domain containing 26