azathioprine-5262 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the azathioprine-5262 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM12 ADAM metallopeptidase domain 12
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AHSP alpha hemoglobin stabilizing protein
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX12 arachidonate 12-lipoxygenase
ALPPL2 alkaline phosphatase, placental-like 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AVIL advillin
B9D2 B9 protein domain 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF95 chromosome 10 open reading frame 95
C3 complement component 3
C8ORF44 chromosome 8 open reading frame 44
CCDC87 coiled-coil domain containing 87
CD47 CD47 molecule
CD52 CD52 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDH10 cadherin 10, type 2 (T2-cadherin)
CLCA1 chloride channel accessory 1
COL6A1 collagen, type VI, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5A cytochrome b5 type A (microsomal)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCN decorin
DEFA4 defensin, alpha 4, corticostatin
DMPK dystrophia myotonica-protein kinase
DTNA dystrobrevin, alpha
EFS embryonal Fyn-associated substrate
ERC2-IT1 ERC2 intronic transcript 1
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGFBP1 fibroblast growth factor binding protein 1
GEMIN8 gem (nuclear organelle) associated protein 8
GHRHR growth hormone releasing hormone receptor
GLYAT glycine-N-acyltransferase
HCAR3 hydroxycarboxylic acid receptor 3
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KRT75 keratin 75, type II
LIMD1 LIM domains containing 1
LINC00260 long intergenic non-protein coding RNA 260
LOC647070 uncharacterized LOC647070
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBD2 methyl-CpG binding domain protein 2
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MIER2 mesoderm induction early response 1, family member 2
MOG myelin oligodendrocyte glycoprotein
MXD4 MAX dimerization protein 4
MYO1B myosin IB
MYT1 myelin transcription factor 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NUP54 nucleoporin 54kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFML2A olfactomedin-like 2A
PARP11 poly (ADP-ribose) polymerase family, member 11
PCDHGA3 protocadherin gamma subfamily A, 3
PCDHGA8 protocadherin gamma subfamily A, 8
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLAC4 placenta-specific 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POPDC3 popeye domain containing 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RETN resistin
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPL35A ribosomal protein L35a
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SRF serum response factor (c-fos serum response element-binding transcription factor)
STK24 serine/threonine kinase 24
SYNDIG1 synapse differentiation inducing 1
SYT11 synaptotagmin XI
TMCC2 transmembrane and coiled-coil domain family 2
TP63 tumor protein p63
TRAIP TRAF interacting protein
TREX1 three prime repair exonuclease 1
TRIL TLR4 interactor with leucine-rich repeats
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSC22D2 TSC22 domain family, member 2
TSPAN2 tetraspanin 2
TYRP1 tyrosinase-related protein 1
UBOX5 U-box domain containing 5
UPK3B uroplakin 3B
ZEB1 zinc finger E-box binding homeobox 1
ZNF223 zinc finger protein 223
ZNF280B zinc finger protein 280B
ZNF3 zinc finger protein 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF749 zinc finger protein 749
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AUTS2 autism susceptibility candidate 2
BMP4 bone morphogenetic protein 4
C14ORF79 chromosome 14 open reading frame 79
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF45 chromosome 5 open reading frame 45
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK20 cyclin-dependent kinase 20
CES3 carboxylesterase 3
CHST10 carbohydrate sulfotransferase 10
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRLF1 cytokine receptor-like factor 1
CXXC4 CXXC finger protein 4
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DVL1 dishevelled segment polarity protein 1
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC6B exocyst complex component 6B
FAM46C family with sequence similarity 46, member C
FBXL6 F-box and leucine-rich repeat protein 6
FGF23 fibroblast growth factor 23
FILIP1L filamin A interacting protein 1-like
FLT4 fms-related tyrosine kinase 4
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR1 G protein-coupled receptor 1
GPR21 G protein-coupled receptor 21
GPR85 G protein-coupled receptor 85
GRB7 growth factor receptor-bound protein 7
GSTP1 glutathione S-transferase pi 1
HAMP hepcidin antimicrobial peptide
HDAC11 histone deacetylase 11
HIST1H2AJ histone cluster 1, H2aj
HIST1H4F histone cluster 1, H4f
HOXC8 homeobox C8
KAT2A K(lysine) acetyltransferase 2A
KDM8 lysine (K)-specific demethylase 8
KIF5A kinesin family member 5A
LGALS4 lectin, galactoside-binding, soluble, 4
LIME1 Lck interacting transmembrane adaptor 1
LOC390998 ribosomal protein L10 pseudogene
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAST3 microtubule associated serine/threonine kinase 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NEK11 NIMA-related kinase 11
NEUROD4 neuronal differentiation 4
NLRX1 NLR family member X1
NPM3 nucleophosmin/nucleoplasmin 3
NPTX1 neuronal pentraxin I
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL1 ovo-like zinc finger 1
PARD6A par-6 family cell polarity regulator alpha
PCDHB13 protocadherin beta 13
PCDHB8 protocadherin beta 8
PCDHGB5 protocadherin gamma subfamily B, 5
PDLIM2 PDZ and LIM domain 2 (mystique)
PENK proenkephalin
PHEX phosphate regulating endopeptidase homolog, X-linked
PIPOX pipecolic acid oxidase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRSS22 protease, serine, 22
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RCAN3 RCAN family member 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
SLC22A14 solute carrier family 22, member 14
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLPI secretory leukocyte peptidase inhibitor
SOX12 SRY (sex determining region Y)-box 12
SOX9 SRY (sex determining region Y)-box 9
STARD3 StAR-related lipid transfer (START) domain containing 3
STIM1 stromal interaction molecule 1
TAS2R10 taste receptor, type 2, member 10
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TOP3B topoisomerase (DNA) III beta
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
VLDLR very low density lipoprotein receptor
VSIG10 V-set and immunoglobulin domain containing 10
WDR62 WD repeat domain 62
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX3 zinc finger homeobox 3
ZFHX4 zinc finger homeobox 4
ZIC3 Zic family member 3
ZNF324 zinc finger protein 324