axon degeneration Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005405
Similar Terms
Downloads & Tools

Genes

56 gene mutations causing the axon degeneration phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
AFG3L2 AFG3-like AAA ATPase 2
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ASPA aspartoacylase
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CHP1 calcineurin-like EF-hand protein 1
CISD2 CDGSH iron sulfur domain 2
CLCN1 chloride channel, voltage-sensitive 1
CLCN2 chloride channel, voltage-sensitive 2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLP1 cleavage and polyadenylation factor I subunit 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTF ciliary neurotrophic factor
DOCK3 dedicator of cytokinesis 3
DST dystonin
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans)
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
GALC galactosylceramidase
GARS glycyl-tRNA synthetase
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KIF1A kinesin family member 1A
KLC1 kinesin light chain 1
LPIN1 lipin 1
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LYNX1 Ly6/neurotoxin 1
MAG myelin associated glycoprotein
MTMR2 myotubularin related protein 2
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
NKX6-2 NK6 homeobox 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLP1 proteolipid protein 1
PMP22 peripheral myelin protein 22
PSAP prosaposin
REEP1 receptor accessory protein 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOD2 superoxide dismutase 2, mitochondrial
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPTBN4 spectrin, beta, non-erythrocytic 4
STMN1 stathmin 1
STXBP1 syntaxin binding protein 1
TBCE tubulin folding cofactor E
UBE4B ubiquitination factor E4B
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VEGFA vascular endothelial growth factor A