autoimmunity Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002960
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Genes

147 genes associated with the autoimmunity phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
GTF2I general transcription factor IIi 2.59154
CFB complement factor B 2.12499
C6ORF10 chromosome 6 open reading frame 10 2.07628
HLA-DRA major histocompatibility complex, class II, DR alpha 1.96108
STAT4 signal transducer and activator of transcription 4 1.84688
BTNL2 butyrophilin-like 2 1.81636
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.66692
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.53321
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.48952
MICB MHC class I polypeptide-related sequence B 1.45905
TNPO3 transportin 3 1.31404
GPR19 G protein-coupled receptor 19 1.27072
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.25845
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.24751
NOTCH4 notch 4 1.2439
CD80 CD80 molecule 1.22503
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 1.19719
HCG26 HLA complex group 26 (non-protein coding) 1.14627
BLK BLK proto-oncogene, Src family tyrosine kinase 1.14469
STK19 serine/threonine kinase 19 1.13056
UHRF1BP1 UHRF1 binding protein 1 1.04365
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.99234
WDFY4 WDFY family member 4 0.97962
LOC100506023 uncharacterized LOC100506023 0.976164
C6ORF106 chromosome 6 open reading frame 106 0.970541
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.931243
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.931243
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.919541
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.909907
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.884852
PXK PX domain containing serine/threonine kinase 0.881851
ARID5B AT rich interactive domain 5B (MRF1-like) 0.881851
HCG23 HLA complex group 23 (non-protein coding) 0.859368
KIAA0319L KIAA0319-like 0.844241
TNXB tenascin XB 0.841148
ATF6B activating transcription factor 6 beta 0.807106
PHRF1 PHD and ring finger domains 1 0.788376
FAM167A-AS1 FAM167A antisense RNA 1 0.772842
MSH5 mutS homolog 5 0.769207
LRRC18 leucine rich repeat containing 18 0.752938
HSPA1L heat shock 70kDa protein 1-like 0.731062
TNIP1 TNFAIP3 interacting protein 1 0.676552
LYN LYN proto-oncogene, Src family tyrosine kinase 0.610342
IRF5 interferon regulatory factor 5 0.610342
AFF1 AF4/FMR2 family, member 1 0.584959
C10ORF11 chromosome 10 open reading frame 11 0.575639
ELF1 E74-like factor 1 (ets domain transcription factor) 0.572823
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 0.567261
HIP1 huntingtin interacting protein 1 0.542759
CREBL2 cAMP responsive element binding protein-like 2 0.542759
JAZF1 JAZF zinc finger 1 0.542759
MUC22 mucin 22 0.534262
CLDN10 claudin 10 0.530944
SLC44A4 solute carrier family 44, member 4 0.523285
C2 complement component 2 0.520753
APOM apolipoprotein M 0.518618
ST18 suppression of tumorigenicity 18, zinc finger 0.516504
IL12RB2 interleukin 12 receptor, beta 2 0.501448
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.493279
SCUBE1 signal peptide, CUB domain, EGF-like 1 0.489878
ATG5 autophagy related 5 0.486378
CDSN corneodesmosin 0.479543
ICA1 islet cell autoantigen 1, 69kDa 0.475642
SAMD9L sterile alpha motif domain containing 9-like 0.474018
CD247 CD247 molecule 0.46699
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.4604
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.446809
CLEC16A C-type lectin domain family 16, member A 0.443208
ZSCAN26 zinc finger and SCAN domain containing 26 0.442291
AVEN apoptosis, caspase activation inhibitor 0.441525
ZNF112 zinc finger protein 112 0.440779
MUC21 mucin 21, cell surface associated 0.439476
LAMC2 laminin, gamma 2 0.437499
LINC00305 long intergenic non-protein coding RNA 305 0.435526
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.43402
GRB2 growth factor receptor-bound protein 2 0.427657
CLCA1 chloride channel accessory 1 0.423203
BANP BTG3 associated nuclear protein 0.421171
MACROD2 MACRO domain containing 2 0.420697
DLG2 discs, large homolog 2 (Drosophila) 0.417242
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.416596
CNTNAP2 contactin associated protein-like 2 0.416054
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.416054
BBS5 Bardet-Biedl syndrome 5 0.415602
LEF1 lymphoid enhancer-binding factor 1 0.413807
GRK4 G protein-coupled receptor kinase 4 0.413807
YDJC YdjC homolog (bacterial) 0.413288
AUH AU RNA binding protein/enoyl-CoA hydratase 0.412088
UPK1B uroplakin 1B 0.411199
DPH2 DPH2 homolog (S. cerevisiae) 0.410979
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.410844
STPG2 sperm-tail PG-rich repeat containing 2 0.410765
TTC7A tetratricopeptide repeat domain 7A 0.410558
NTNG2 netrin G2 0.410331
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.410331
RHPN2 rhophilin, Rho GTPase binding protein 2 0.409851
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.409759
PDE4B phosphodiesterase 4B, cAMP-specific 0.409271
ANKRD44 ankyrin repeat domain 44 0.407698
ANXA6 annexin A6 0.407192
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.406676
TCF19 transcription factor 19 0.405769
LY6G6C lymphocyte antigen 6 complex, locus G6C 0.405654
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 0.405267
ZSCAN31 zinc finger and SCAN domain containing 31 0.405091
ZNRD1 zinc ribbon domain containing 1 0.405041
OR4A15 olfactory receptor, family 4, subfamily A, member 15 0.40409
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.40409
NEGR1 neuronal growth regulator 1 0.40409
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.40409
MOB3B MOB kinase activator 3B 0.40409
BTN2A1 butyrophilin, subfamily 2, member A1 0.403403
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.403073
TMC2 transmembrane channel-like 2 0.403073
HSPA1B heat shock 70kDa protein 1B 0.402941
PGBD1 piggyBac transposable element derived 1 0.402903
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.402514
HCG9 HLA complex group 9 (non-protein coding) 0.400299
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.400089
SRCIN1 SRC kinase signaling inhibitor 1 0.399953
PRRC2A proline-rich coiled-coil 2A 0.399242
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.399242
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.397761
PLXNA4 plexin A4 0.397418
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.397363
DPCR1 diffuse panbronchiolitis critical region 1 0.397197
RNF39 ring finger protein 39 0.396823
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.396413
PUM1 pumilio RNA-binding family member 1 0.394816
PVT1 Pvt1 oncogene (non-protein coding) 0.39272
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.391575
TSPAN11 tetraspanin 11 0.390842
VWA7 von Willebrand factor A domain containing 7 0.390189
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.389544
HIC2 hypermethylated in cancer 2 0.385085
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.379492
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.378224
LPAR1 lysophosphatidic acid receptor 1 0.374155
AVL9 AVL9 homolog (S. cerevisiase) 0.373119
LRRC20 leucine rich repeat containing 20 0.370443
AKAP2 A kinase (PRKA) anchor protein 2 0.36951
VSIG2 V-set and immunoglobulin domain containing 2 0.366942
TMEM39A transmembrane protein 39A 0.364609
IP6K3 inositol hexakisphosphate kinase 3 0.363702
RSBN1 round spermatid basic protein 1 0.363153
SOX5 SRY (sex determining region Y)-box 5 0.361585
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.352924