atp-sensitive potassium channel complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.2 subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SUR1 subunit stimulates channel activity. (Gene Ontology, GO_0008282)
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95 proteins co-occuring with the atp-sensitive potassium channel complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 3.29616
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 3.14461
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.44436
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 1.82931
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 1.77992
INS insulin 1.55764
ADORA1 adenosine A1 receptor 1.36692
GUCY2C guanylate cyclase 2C 1.04632
NPR1 natriuretic peptide receptor 1 1.03579
GLUD1 glutamate dehydrogenase 1 0.887474
KNG1 kininogen 1 0.880555
GCK glucokinase (hexokinase 4) 0.855257
CTH cystathionine gamma-lyase 0.848369
NRK Nik related kinase 0.846073
ENSA endosulfine alpha 0.738713
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.736464
HADH hydroxyacyl-CoA dehydrogenase 0.672894
CALCA calcitonin-related polypeptide alpha 0.628187
GLI1 GLI family zinc finger 1 0.626483
PDE5A phosphodiesterase 5A, cGMP-specific 0.60655
LEP leptin 0.597276
FOXF2 forkhead box F2 0.588456
DEGS2 delta(4)-desaturase, sphingolipid 2 0.587618
GCG glucagon 0.573411
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.571745
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.543176
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.542352
CSN3 casein kappa 0.513677
EDN1 endothelin 1 0.475223
NOS3 nitric oxide synthase 3 (endothelial cell) 0.470807
STC1 stanniocalcin 1 0.441312
EPHX2 epoxide hydrolase 2, cytoplasmic 0.432618
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.415728
SPATA21 spermatogenesis associated 21 0.413382
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.410649
SOD2 superoxide dismutase 2, mitochondrial 0.399363
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.397811
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.397035
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.361659
MGAM maltase-glucoamylase 0.355563
GAL galanin/GMAP prepropeptide 0.340395
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.329837
CAT catalase 0.325327
SP8 Sp8 transcription factor 0.324951
LEPR leptin receptor 0.321201
JUN jun proto-oncogene 0.319702
STX1A syntaxin 1A (brain) 0.310358
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.307377
RPIA ribose 5-phosphate isomerase A 0.304771
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.303283
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.297342
ADM2 adrenomedullin 2 0.294378
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.28846
GIP gastric inhibitory polypeptide 0.281085
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.278877
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.278141
AKTIP AKT interacting protein 0.277406
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.276304
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.276304
CBS cystathionine-beta-synthase 0.274101
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.271167
PLSCR3 phospholipid scramblase 3 0.265677
QPCT glutaminyl-peptide cyclotransferase 0.264946
LAD1 ladinin 1 0.258381
NPY neuropeptide Y 0.25547
HCRT hypocretin (orexin) neuropeptide precursor 0.251476
EDN3 endothelin 3 0.251476
FFAR1 free fatty acid receptor 1 0.246407
DNAH8 dynein, axonemal, heavy chain 8 0.245323
REN renin 0.239916
PSAT1 phosphoserine aminotransferase 1 0.224913
BAX BCL2-associated X protein 0.221378
NPPA natriuretic peptide A 0.219265
DNTT DNA nucleotidylexotransferase 0.215761
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.215063
EDNRA endothelin receptor type A 0.21228
CDO1 cysteine dioxygenase type 1 0.208137
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.207794
HLA-DOB major histocompatibility complex, class II, DO beta 0.207794
ADCY2 adenylate cyclase 2 (brain) 0.196999
HNF4A hepatocyte nuclear factor 4, alpha 0.186087
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.183935
NLRP12 NLR family, pyrin domain containing 12 0.183025
GHRL ghrelin/obestatin prepropeptide 0.181823
TNNT2 troponin T type 2 (cardiac) 0.179167
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.178588
CCK cholecystokinin 0.174911
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.173273
HDX highly divergent homeobox 0.16935
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.16935
INSR insulin receptor 0.168349
C21ORF2 chromosome 21 open reading frame 2 0.165231
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.160863
GPER1 G protein-coupled estrogen receptor 1 0.160053
ANXA4 annexin A4 0.159074