asthma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety. (Human Disease Ontology, DOID_2841)
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Genes

1090 genes co-occuring with the disease asthma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RNASE3 ribonuclease, RNase A family, 3 2.77145
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 2.58223
IL5 interleukin 5 2.45537
IL13 interleukin 13 2.27637
ADRB2 adrenoceptor beta 2, surface 2.27322
IL4 interleukin 4 2.24098
CD4 CD4 molecule 2.21751
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 2.19084
ADAM33 ADAM metallopeptidase domain 33 2.17706
EPX eosinophil peroxidase 2.12368
TSLP thymic stromal lymphopoietin 2.11974
FLNC filamin C, gamma 2.0735
PDE4A phosphodiesterase 4A, cAMP-specific 2.07168
CCL11 chemokine (C-C motif) ligand 11 2.06216
CCR3 chemokine (C-C motif) receptor 3 2.02974
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.97036
LTC4S leukotriene C4 synthase 1.89684
ALOX5 arachidonate 5-lipoxygenase 1.88021
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.87745
TAC1 tachykinin, precursor 1 1.87148
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.86781
GATA3 GATA binding protein 3 1.85547
ICAM1 intercellular adhesion molecule 1 1.82368
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.81374
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.80201
CYSLTR1 cysteinyl leukotriene receptor 1 1.80156
IL4R interleukin 4 receptor 1.79796
PTGDR2 prostaglandin D2 receptor 2 1.78759
KIAA0101 KIAA0101 1.77812
CYSLTR2 cysteinyl leukotriene receptor 2 1.77767
CCL17 chemokine (C-C motif) ligand 17 1.76547
TNF tumor necrosis factor 1.76547
NPS neuropeptide S 1.74506
TGFB1 transforming growth factor, beta 1 1.72137
KNG1 kininogen 1 1.68725
IL1B interleukin 1, beta 1.67457
FOXP3 forkhead box P3 1.666
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 1.65025
NEUROD1 neuronal differentiation 1 1.64218
CXCL8 chemokine (C-X-C motif) ligand 8 1.63904
CHIA chitinase, acidic 1.63276
TBX21 T-box 21 1.63097
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 1.6256
ALB albumin 1.61083
CD79A CD79a molecule, immunoglobulin-associated alpha 1.59117
CCL13 chemokine (C-C motif) ligand 13 1.58046
NPSR1 neuropeptide S receptor 1 1.57913
TACR2 tachykinin receptor 2 1.57556
FLG filaggrin 1.56622
IL9 interleukin 9 1.56533
CLCA1 chloride channel accessory 1 1.55956
VCAM1 vascular cell adhesion molecule 1 1.55468
TLR4 toll-like receptor 4 1.55468
POMC proopiomelanocortin 1.54893
HRH1 histamine receptor H1 1.54054
IL1RL1 interleukin 1 receptor-like 1 1.5304
CCL24 chemokine (C-C motif) ligand 24 1.52996
MPO myeloperoxidase 1.50886
PHF11 PHD finger protein 11 1.50316
CCL22 chemokine (C-C motif) ligand 22 1.49526
C5AR1 complement component 5a receptor 1 1.47945
DPP10 dipeptidyl-peptidase 10 (non-functional) 1.45572
CXCL10 chemokine (C-X-C motif) ligand 10 1.45177
GSDMB gasdermin B 1.43639
MMP9 matrix metallopeptidase 9 1.43596
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 1.42279
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.41884
CCL2 chemokine (C-C motif) ligand 2 1.41358
TSPO translocator protein (18kDa) 1.39214
CD86 CD86 molecule 1.38603
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.38559
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.38516
CCL5 chemokine (C-C motif) ligand 5 1.38472
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.38428
LTB4R leukotriene B4 receptor 1.3821
CMA1 chymase 1, mast cell 1.37381
PTGDR prostaglandin D2 receptor (DP) 1.37076
HRH4 histamine receptor H4 1.36509
TLR2 toll-like receptor 2 1.35856
FN1 fibronectin 1 1.35681
IL10 interleukin 10 1.35638
CCL26 chemokine (C-C motif) ligand 26 1.35333
TACR1 tachykinin receptor 1 1.34199
TBXA2R thromboxane A2 receptor 1.32279
HDAC2 histone deacetylase 2 1.29746
MED28 mediator complex subunit 28 1.29527
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.29221
CRLF2 cytokine receptor-like factor 2 1.28261
CCL3 chemokine (C-C motif) ligand 3 1.27563
TLR3 toll-like receptor 3 1.27432
VIP vasoactive intestinal peptide 1.26429
NGF nerve growth factor (beta polypeptide) 1.26386
TIMP1 TIMP metallopeptidase inhibitor 1 1.25297
GSTP1 glutathione S-transferase pi 1 1.25297
CCR8 chemokine (C-C motif) receptor 8 1.2508
PDC phosducin 1.24472
GSTM1 glutathione S-transferase mu 1 1.23994
MYLK myosin light chain kinase 1.2395
NELFCD negative elongation factor complex member C/D 1.23473
IL17A interleukin 17A 1.22865
CD69 CD69 molecule 1.22475
GSTA1 glutathione S-transferase alpha 1 1.22172
IL33 interleukin 33 1.22172
IL18R1 interleukin 18 receptor 1 1.22042
TLR9 toll-like receptor 9 1.21089
SYK spleen tyrosine kinase 1.20959
ACE angiotensin I converting enzyme 1.20483
ADAM8 ADAM metallopeptidase domain 8 1.20396
ELANE elastase, neutrophil expressed 1.19877
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.19748
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.19532
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.19489
GSTA2 glutathione S-transferase alpha 2 1.191
GSTA3 glutathione S-transferase alpha 3 1.18152
GSTA4 glutathione S-transferase alpha 4 1.17894
CD80 CD80 molecule 1.17894
CXCR2 chemokine (C-X-C motif) receptor 2 1.17722
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.17035
SCGB3A2 secretoglobin, family 3A, member 2 1.16992
EDN1 endothelin 1 1.16435
JUN jun proto-oncogene 1.15453
CD276 CD276 molecule 1.1541
ADCY2 adenylate cyclase 2 (brain) 1.1524
LEP leptin 1.15198
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 1.14136
TLR7 toll-like receptor 7 1.13924
PDE4D phosphodiesterase 4D, cAMP-specific 1.12151
IL6 interleukin 6 1.12066
CCL7 chemokine (C-C motif) ligand 7 1.11435
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.11351
CRP C-reactive protein, pentraxin-related 1.11267
IL5RA interleukin 5 receptor, alpha 1.11057
SIGLEC8 sialic acid binding Ig-like lectin 8 1.10931
TPT1 tumor protein, translationally-controlled 1 1.10678
SELL selectin L 1.10552
PDCL phosducin-like 1.1051
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.1051
IL2RA interleukin 2 receptor, alpha 1.08663
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.08621
ITK IL2-inducible T-cell kinase 1.08579
IL16 interleukin 16 1.08454
CD40 CD40 molecule, TNF receptor superfamily member 5 1.08202
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.0795
CLNK cytokine-dependent hematopoietic cell linker 1.07908
NOS2 nitric oxide synthase 2, inducible 1.07152
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.0711
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 1.07026
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.06732
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.0648
GSTTP1 glutathione S-transferase theta pseudogene 1 1.06186
GSTT1 glutathione S-transferase theta 1 1.06186
CXCR3 chemokine (C-X-C motif) receptor 3 1.0585
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.05639
FAM188A family with sequence similarity 188, member A 1.05177
MME membrane metallo-endopeptidase 1.04251
TNC tenascin C 1.04167
HNMT histamine N-methyltransferase 1.03704
SOD2 superoxide dismutase 2, mitochondrial 1.03409
CCL20 chemokine (C-C motif) ligand 20 1.02988
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 1.02945
YBX2 Y box binding protein 2 1.02735
TIMD4 T-cell immunoglobulin and mucin domain containing 4 1.02397
ZPBP2 zona pellucida binding protein 2 1.01638
PLA2G1B phospholipase A2, group IB (pancreas) 1.01469
SELE selectin E 1.01469
C3AR1 complement component 3a receptor 1 0.998236
SPINK5 serine peptidase inhibitor, Kazal type 5 0.997392
CPA3 carboxypeptidase A3 (mast cell) 0.993596
MYD88 myeloid differentiation primary response 88 0.991065
GPX1 glutathione peroxidase 1 0.980531
PFN4 profilin family, member 4 0.979268
IL17RB interleukin 17 receptor B 0.965405
IL18 interleukin 18 0.964986
GLCCI1 glucocorticoid induced 1 0.962053
PPARG peroxisome proliferator-activated receptor gamma 0.954943
CAT catalase 0.954525
GPX4 glutathione peroxidase 4 0.948269
CALCA calcitonin-related polypeptide alpha 0.947852
ALOX15 arachidonate 15-lipoxygenase 0.947019
IL2 interleukin 2 0.947019
F2 coagulation factor II (thrombin) 0.939949
PFN1 profilin 1 0.938704
HBA2 hemoglobin, alpha 2 0.938704
SFTPD surfactant protein D 0.937459
GSDMA gasdermin A 0.937044
GPX5 glutathione peroxidase 5 0.937044
IL3 interleukin 3 0.932898
CXCR1 chemokine (C-X-C motif) receptor 1 0.932484
CD1D CD1d molecule 0.931242
BDNF brain-derived neurotrophic factor 0.927105
STAT1 signal transducer and activator of transcription 1, 91kDa 0.912257
DERL1 derlin 1 0.911022
LTA4H leukotriene A4 hydrolase 0.909787
CCR1 chemokine (C-C motif) receptor 1 0.909787
RETNLB resistin like beta 0.909376
PFN2 profilin 2 0.906498
MAPK8 mitogen-activated protein kinase 8 0.906086
BGLAP bone gamma-carboxyglutamate (gla) protein 0.900335
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.899924
LARS leucyl-tRNA synthetase 0.899514
TLR10 toll-like receptor 10 0.893769
CCL1 chemokine (C-C motif) ligand 1 0.890898
CCL8 chemokine (C-C motif) ligand 8 0.890488
NOD1 nucleotide-binding oligomerization domain containing 1 0.890488
CCR2 chemokine (C-C motif) receptor 2 0.887208
LAG3 lymphocyte-activation gene 3 0.882292
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.880243
PEF1 penta-EF-hand domain containing 1 0.879014
ZNF12 zinc finger protein 12 0.876557
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.875738
IDO1 indoleamine 2,3-dioxygenase 1 0.874509
ARG1 arginase 1 0.872462
CPA4 carboxypeptidase A4 0.870415
CXCL5 chemokine (C-X-C motif) ligand 5 0.859771
MAPK14 mitogen-activated protein kinase 14 0.858134
TPM1 tropomyosin 1 (alpha) 0.856087
BTNL2 butyrophilin-like 2 0.853631
IL13RA1 interleukin 13 receptor, alpha 1 0.850764
TLR6 toll-like receptor 6 0.848716
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.848716
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.848307
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.846669
DENND1B DENN/MADD domain containing 1B 0.84585
HLA-C major histocompatibility complex, class I, C 0.842982
MMP2 matrix metallopeptidase 2 0.842982
SOCS3 suppressor of cytokine signaling 3 0.841344
CHIT1 chitinase 1 (chitotriosidase) 0.835198
PCDH1 protocadherin 1 0.834378
PTAFR platelet-activating factor receptor 0.827409
HDAC9 histone deacetylase 9 0.823308
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.822077
LTA lymphotoxin alpha 0.821257
IFNG interferon, gamma 0.820437
PDE4B phosphodiesterase 4B, cAMP-specific 0.818796
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.816745
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.816745
NPEPPS aminopeptidase puromycin sensitive 0.814693
INS insulin 0.812232
ARRB2 arrestin, beta 2 0.800333
HLA-G major histocompatibility complex, class I, G 0.798282
CD19 CD19 molecule 0.785984
LYN LYN proto-oncogene, Src family tyrosine kinase 0.785165
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.785165
ICK intestinal cell (MAK-like) kinase 0.784755
CREB1 cAMP responsive element binding protein 1 0.782707
PGF placental growth factor 0.778204
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.777386
VCAN versican 0.776977
TLR1 toll-like receptor 1 0.775341
CXCL2 chemokine (C-X-C motif) ligand 2 0.773296
CD40LG CD40 ligand 0.771661
ORM1 orosomucoid 1 0.76921
MGAM maltase-glucoamylase 0.768393
EGFR epidermal growth factor receptor 0.766759
NOS1 nitric oxide synthase 1 (neuronal) 0.765535
CARD17 caspase recruitment domain family, member 17 0.765535
SELPLG selectin P ligand 0.765127
IL17RC interleukin 17 receptor C 0.762678
GPR35 G protein-coupled receptor 35 0.761454
SMAD2 SMAD family member 2 0.760231
CD34 CD34 molecule 0.756564
IL7R interleukin 7 receptor 0.756156
FOS FBJ murine osteosarcoma viral oncogene homolog 0.755749
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.752898
MMP1 matrix metallopeptidase 1 0.752085
LOX lysyl oxidase 0.752085
LTF lactotransferrin 0.750864
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.750457
FBXO8 F-box protein 8 0.749644
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.74883
CD68 CD68 molecule 0.74761
CCL4 chemokine (C-C motif) ligand 4 0.74761
PDCD1LG2 programmed cell death 1 ligand 2 0.747204
CRHR1 corticotropin releasing hormone receptor 1 0.746798
CSN1S1 casein alpha s1 0.746391
ANXA5 annexin A5 0.744766
HMOX1 heme oxygenase 1 0.743954
CD44 CD44 molecule (Indian blood group) 0.742735
ITLN2 intelectin 2 0.733811
IRF1 interferon regulatory factor 1 0.729762
MUC2 mucin 2, oligomeric mucus/gel-forming 0.728952
CCR7 chemokine (C-C motif) receptor 7 0.728952
MMP12 matrix metallopeptidase 12 0.727738
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.726929
GPR68 G protein-coupled receptor 68 0.724502
IL1A interleukin 1, alpha 0.724098
C6ORF25 chromosome 6 open reading frame 25 0.723694
HPGDS hematopoietic prostaglandin D synthase 0.722077
SPDEF SAM pointed domain containing ETS transcription factor 0.72127
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.720058
LTB4R2 leukotriene B4 receptor 2 0.716425
CHRM3 cholinergic receptor, muscarinic 3 0.715215
TCHH trichohyalin 0.715215
MARCKS myristoylated alanine-rich protein kinase C substrate 0.709572
SPRR2B small proline-rich protein 2B 0.708767
CHRM2 cholinergic receptor, muscarinic 2 0.705547
JAK2 Janus kinase 2 0.703134
PER1 period circadian clock 1 0.703134
HRH2 histamine receptor H2 0.702732
SOCS5 suppressor of cytokine signaling 5 0.701124
IL1RN interleukin 1 receptor antagonist 0.699116
HSH2D hematopoietic SH2 domain containing 0.698313
MAPK3 mitogen-activated protein kinase 3 0.697109
SETDB2 SET domain, bifurcated 2 0.693098
CD63 CD63 molecule 0.688692
ADA adenosine deaminase 0.687491
ACTG1 actin gamma 1 0.687091
CKLF chemokine-like factor 0.686691
IRAK3 interleukin-1 receptor-associated kinase 3 0.686291
WAPAL wings apart-like homolog (Drosophila) 0.679898
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.679499
GGACT gamma-glutamylamine cyclotransferase 0.677504
TFF2 trefoil factor 2 0.677105
FAM21C family with sequence similarity 21, member C 0.675909
MRC1 mannose receptor, C type 1 0.67551
IL2RB interleukin 2 receptor, beta 0.675112
IGHE immunoglobulin heavy constant epsilon 0.674315
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.673917
FKBP5 FK506 binding protein 5 0.673518
ACTB actin, beta 0.667152
CXCL9 chemokine (C-X-C motif) ligand 9 0.662387
CCR6 chemokine (C-C motif) receptor 6 0.66199
NOS3 nitric oxide synthase 3 (endothelial cell) 0.661594
LAP3 leucine aminopeptidase 3 0.661594
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.6608
NTF3 neurotrophin 3 0.658818
AHR aryl hydrocarbon receptor 0.658818
ALPL alkaline phosphatase, liver/bone/kidney 0.658026
COL6A5 collagen, type VI, alpha 5 0.656441
RORA RAR-related orphan receptor A 0.656046
ALPPL2 alkaline phosphatase, placental-like 2 0.651694
ALPP alkaline phosphatase, placental 0.651298
CISH cytokine inducible SH2-containing protein 0.651298
ADAT3 adenosine deaminase, tRNA-specific 3 0.648533
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.646953
FGF2 fibroblast growth factor 2 (basic) 0.646559
ARG2 arginase 2 0.640251
AREG amphiregulin 0.640251
IL17F interleukin 17F 0.639463
NPPA natriuretic peptide A 0.636315
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.635921
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.635921
DCN decorin 0.634742
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.634742
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.634742
CTSG cathepsin G 0.633956
TBXAS1 thromboxane A synthase 1 (platelet) 0.633563
LY96 lymphocyte antigen 96 0.627672
VEGFA vascular endothelial growth factor A 0.627672
IFNA1 interferon, alpha 1 0.62728
PLA2G10 phospholipase A2, group X 0.624535
HDC histidine decarboxylase 0.623751
ADORA1 adenosine A1 receptor 0.622183
FPR2 formyl peptide receptor 2 0.620617
IL9R interleukin 9 receptor 0.61866
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.61866
ARRB1 arrestin, beta 1 0.617877
RETN resistin 0.616312
FOXA2 forkhead box A2 0.615921
ORAI1 ORAI calcium release-activated calcium modulator 1 0.615138
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.613183
MEFV Mediterranean fever 0.61162
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.609276
KAT8 K(lysine) acetyltransferase 8 0.607714
PER2 period circadian clock 2 0.603811
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.60225
PDE7A phosphodiesterase 7A 0.60108
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.60069
HMGB1 high mobility group box 1 0.60069
CLC Charcot-Leyden crystal galectin 0.598351
LAT linker for activation of T cells 0.597181
NOD2 nucleotide-binding oligomerization domain containing 2 0.595233
CDIP1 cell death-inducing p53 target 1 0.593674
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.593285
PF4 platelet factor 4 0.592506
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.591727
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.590948
EDNRA endothelin receptor type A 0.589001
ZNF71 zinc finger protein 71 0.587054
TPSD1 tryptase delta 1 0.586665
RENBP renin binding protein 0.586665
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.586276
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.585887
BGN biglycan 0.585108
IL31 interleukin 31 0.584719
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.584719
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.58433
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.579272
SMAD7 SMAD family member 7 0.578883
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.578106
KLK1 kallikrein 1 0.574605
TLR8 toll-like receptor 8 0.571884
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.571495
STAT4 signal transducer and activator of transcription 4 0.567997
ADORA3 adenosine A3 receptor 0.567609
OXER1 oxoeicosanoid (OXE) receptor 1 0.566831
PRSS30P protease, serine, 30, pseudogene 0.566831
ADRB1 adrenoceptor beta 1 0.566831
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.566443
STIM1 stromal interaction molecule 1 0.565277
EBI3 Epstein-Barr virus induced 3 0.564889
LGALS14 lectin, galactoside-binding, soluble, 14 0.5645
KIDINS220 kinase D-interacting substrate, 220kDa 0.563335
NCF4 neutrophil cytosolic factor 4, 40kDa 0.562946
MGST1 microsomal glutathione S-transferase 1 0.562558
IL19 interleukin 19 0.562169
CD83 CD83 molecule 0.562169
JAK1 Janus kinase 1 0.561781
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.561781
CXCL11 chemokine (C-X-C motif) ligand 11 0.561781
RAD50 RAD50 homolog (S. cerevisiae) 0.55945
PTGES prostaglandin E synthase 0.559062
HHAT hedgehog acyltransferase 0.557509
SLPI secretory leukocyte peptidase inhibitor 0.55518
COL26A1 collagen, type XXVI, alpha 1 0.554791
LYZ lysozyme 0.554403
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.552851
GC group-specific component (vitamin D binding protein) 0.552851
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.552463
PRTN3 proteinase 3 0.551298
HBEGF heparin-binding EGF-like growth factor 0.551298
CRH corticotropin releasing hormone 0.550522
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.548195
SMAD3 SMAD family member 3 0.547807
CD38 CD38 molecule 0.547419
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.546644
HP haptoglobin 0.546256
BTK Bruton agammaglobulinemia tyrosine kinase 0.542379
HPR haptoglobin-related protein 0.540055
TACR3 tachykinin receptor 3 0.540055
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.538893
ICOSLG inducible T-cell co-stimulator ligand 0.537731
CADM1 cell adhesion molecule 1 0.53657
ALK anaplastic lymphoma receptor tyrosine kinase 0.535409
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.533475
LRRC32 leucine rich repeat containing 32 0.532701
CTSS cathepsin S 0.528449
CD48 CD48 molecule 0.528449
GUSB glucuronidase, beta 0.52729
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.526904
ANXA1 annexin A1 0.524202
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.523045
IRAK2 interleukin-1 receptor-associated kinase 2 0.522273
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.518034
IRF3 interferon regulatory factor 3 0.517649
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.515725
TMEM45A transmembrane protein 45A 0.511112
ATAD3A ATPase family, AAA domain containing 3A 0.510344
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.509192
PRRC2A proline-rich coiled-coil 2A 0.509192
FAM13A family with sequence similarity 13, member A 0.509192
NLRP3 NLR family, pyrin domain containing 3 0.508424
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.507657
MGST2 microsomal glutathione S-transferase 2 0.50689
GFRA4 GDNF family receptor alpha 4 0.505356
LGALS9 lectin, galactoside-binding, soluble, 9 0.504973
CTGF connective tissue growth factor 0.504973
KITLG KIT ligand 0.504207
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.499997
NGFR nerve growth factor receptor 0.499614
TXN thioredoxin 0.499614
KAT5 K(lysine) acetyltransferase 5 0.498849
TGFB2 transforming growth factor, beta 2 0.496557
EED embryonic ectoderm development 0.496175
IRF4 interferon regulatory factor 4 0.495793
S100A8 S100 calcium binding protein A8 0.494266
POSTN periostin, osteoblast specific factor 0.493885
DNAH8 dynein, axonemal, heavy chain 8 0.491978
PKDCC protein kinase domain containing, cytoplasmic 0.490835
CHRM1 cholinergic receptor, muscarinic 1 0.490072
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.489311
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.489311
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.488549
AGR2 anterior gradient 2 0.488169
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 0.488169
SPP1 secreted phosphoprotein 1 0.487407
IPO13 importin 13 0.486266
RASGRP4 RAS guanyl releasing protein 4 0.482844
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.482844
LGALS3 lectin, galactoside-binding, soluble, 3 0.480566
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.479807
YY1 YY1 transcription factor 0.479427
MUC7 mucin 7, secreted 0.479047
IGF1 insulin-like growth factor 1 (somatomedin C) 0.478668
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.478289
ANGPT1 angiopoietin 1 0.476393
LPO lactoperoxidase 0.47374
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.473361
SART1 squamous cell carcinoma antigen recognized by T cells 0.472604
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.470711
TOLLIP toll interacting protein 0.470711
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 0.470332
EGR1 early growth response 1 0.468819
ANK1 ankyrin 1, erythrocytic 0.467684
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.466928
CAV1 caveolin 1, caveolae protein, 22kDa 0.463905
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.463905
IFNGR1 interferon gamma receptor 1 0.463527
CAMP cathelicidin antimicrobial peptide 0.463149
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 0.462016
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.461261
HSPA4 heat shock 70kDa protein 4 0.460883
TSC22D3 TSC22 domain family, member 3 0.459751
BATF basic leucine zipper transcription factor, ATF-like 0.459373
DPCR1 diffuse panbronchiolitis critical region 1 0.45447
CDHR3 cadherin-related family member 3 0.45447
UBQLN4 ubiquilin 4 0.45447
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 0.45447
FAM181A family with sequence similarity 181, member A 0.45447
ANKEF1 ankyrin repeat and EF-hand domain containing 1 0.45447
SMAP2 small ArfGAP2 0.45447
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.454093
PC pyruvate carboxylase 0.453339
NTF4 neurotrophin 4 0.449571
TIMP2 TIMP metallopeptidase inhibitor 2 0.447687
DPT dermatopontin 0.445805
PLG plasminogen 0.444676
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.4443
JAK3 Janus kinase 3 0.442042
TAGLN transgelin 0.441666
AQP5 aquaporin 5 0.439786
ADORA2B adenosine A2b receptor 0.43941
OCLN occludin 0.437906
FYN FYN proto-oncogene, Src family tyrosine kinase 0.436778
TTC25 tetratricopeptide repeat domain 25 0.434524
BPIFB1 BPI fold containing family B, member 1 0.434524
RAP1GAP2 RAP1 GTPase activating protein 2 0.434524
GLRA4 glycine receptor, alpha 4 0.434524
CCDC69 coiled-coil domain containing 69 0.434524
SKIDA1 SKI/DACH domain containing 1 0.434524
SLC22A15 solute carrier family 22, member 15 0.434524
ZSCAN31 zinc finger and SCAN domain containing 31 0.434524
PARP1 poly (ADP-ribose) polymerase 1 0.433772
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 0.432646
ADGRA1 adhesion G protein-coupled receptor A1 0.431519
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.431144
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.42589
PDE5A phosphodiesterase 5A, cGMP-specific 0.424014
ELP2 elongator acetyltransferase complex subunit 2 0.42364
FFAR2 free fatty acid receptor 2 0.42289
PPARA peroxisome proliferator-activated receptor alpha 0.420266
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.419892
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.419142
GGTLC2 gamma-glutamyltransferase light chain 2 0.418019
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.416521
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 0.415024
ALOX12 arachidonate 12-lipoxygenase 0.411657
ZFP30 ZFP30 zinc finger protein 0.410161
IGLV2-14 immunoglobulin lambda variable 2-14 0.409414
PI3 peptidase inhibitor 3, skin-derived 0.408666
GNLY granulysin 0.408666
FASLG Fas ligand (TNF superfamily, member 6) 0.408292
SLC35E2B solute carrier family 35, member E2B 0.405305
PCNA proliferating cell nuclear antigen 0.404931
ANKRD42 ankyrin repeat domain 42 0.403811
ACSL3 acyl-CoA synthetase long-chain family member 3 0.403438
RLN3 relaxin 3 0.401945
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.401945
SIGLEC14 sialic acid binding Ig-like lectin 14 0.401199
IARS isoleucyl-tRNA synthetase 0.401199
NMUR1 neuromedin U receptor 1 0.40008
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.40008
PNMT phenylethanolamine N-methyltransferase 0.399707
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.397471
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.396353
GGT5 gamma-glutamyltransferase 5 0.396353
GSTO2 glutathione S-transferase omega 2 0.395608
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.394491
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 0.393374
PLAU plasminogen activator, urokinase 0.392257
CPSF3L cleavage and polyadenylation specific factor 3-like 0.390769
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.390397
CD9 CD9 molecule 0.390397
C1ORF167 chromosome 1 open reading frame 167 0.390025
SPHK1 sphingosine kinase 1 0.388909
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.388538
OR52J3 olfactory receptor, family 52, subfamily J, member 3 0.388538
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.387794
NMUR2 neuromedin U receptor 2 0.386308
BCHE butyrylcholinesterase 0.385565
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.385193
UBE3C ubiquitin protein ligase E3C 0.384822
FPR1 formyl peptide receptor 1 0.384451
CCL27 chemokine (C-C motif) ligand 27 0.384079
BTLA B and T lymphocyte associated 0.382966
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.382966
SMTNL1 smoothelin-like 1 0.382223
LCN1 lipocalin 1 0.381481
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.379626
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 0.374809
S1PR2 sphingosine-1-phosphate receptor 2 0.374438
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.374068
CXCL12 chemokine (C-X-C motif) ligand 12 0.371847
IL1R1 interleukin 1 receptor, type I 0.371107
CD1C CD1c molecule 0.368518
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.36741
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.365932
MAGEC3 melanoma antigen family C3 0.365193
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.364085
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.360026
LOXL1 lysyl oxidase-like 1 0.358183
TLR5 toll-like receptor 5 0.357814
CD209 CD209 molecule 0.357446
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.357446
IRF7 interferon regulatory factor 7 0.357446
FGFBP2 fibroblast growth factor binding protein 2 0.356341
NAAA N-acylethanolamine acid amidase 0.355972
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.354131
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.353395
GSR glutathione reductase 0.352659
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.351923
MMP25 matrix metallopeptidase 25 0.351923
CDH26 cadherin 26 0.351187
CCL15 chemokine (C-C motif) ligand 15 0.35082
GPANK1 G patch domain and ankyrin repeats 1 0.350452
FOXA3 forkhead box A3 0.348981
POLK polymerase (DNA directed) kappa 0.347511
NTS neurotensin 0.347144
ADAM17 ADAM metallopeptidase domain 17 0.346042
PM20D1 peptidase M20 domain containing 1 0.344941
BAX BCL2-associated X protein 0.344574
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.34384
EPHA4 EPH receptor A4 0.342006
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.341639
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.341639
GPR65 G protein-coupled receptor 65 0.341272
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.340539
HMOX2 heme oxygenase 2 0.339073
ZHX2 zinc fingers and homeoboxes 2 0.338707
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.337242
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.336876
SFTPA1 surfactant protein A1 0.336876
AIRE autoimmune regulator 0.33651
FOXJ1 forkhead box J1 0.335778
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.335046
A2M alpha-2-macroglobulin 0.335046
LELP1 late cornified envelope-like proline-rich 1 0.335046
POM121L2 POM121 transmembrane nucleoporin-like 2 0.335046
HLA-DMA major histocompatibility complex, class II, DM alpha 0.332487
FAM129A family with sequence similarity 129, member A 0.332121
RAG2 recombination activating gene 2 0.331391
AGER advanced glycosylation end product-specific receptor 0.33066
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.33066
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.33066
ZFPM1 zinc finger protein, FOG family member 1 0.32993
CNKSR3 CNKSR family member 3 0.32993
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.3292
HAND1 heart and neural crest derivatives expressed 1 0.328105
CCND1 cyclin D1 0.327375
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.32701
EHF ets homologous factor 0.325916
MYH11 myosin, heavy chain 11, smooth muscle 0.325916
CPN1 carboxypeptidase N, polypeptide 1 0.324094
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.323365
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.323002
CORT cortistatin 0.322637
IL1R2 interleukin 1 receptor, type II 0.322637
PYHIN1 pyrin and HIN domain family, member 1 0.321545
IL27RA interleukin 27 receptor, alpha 0.321545
LCK LCK proto-oncogene, Src family tyrosine kinase 0.320817
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.320454
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.32009
THBD thrombomodulin 0.319363
ADSS adenylosuccinate synthase 0.318635
ANG angiogenin, ribonuclease, RNase A family, 5 0.317909
MLX MLX, MAX dimerization protein 0.317909
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.317182
PER3 period circadian clock 3 0.316092
USP38 ubiquitin specific peptidase 38 0.314278
HAS2 hyaluronan synthase 2 0.314278
STAC3 SH3 and cysteine rich domain 3 0.314278
FKBP4 FK506 binding protein 4, 59kDa 0.314278
ERO1LB ERO1-like beta (S. cerevisiae) 0.313552
MBL2 mannose-binding lectin (protein C) 2, soluble 0.312464
PRF1 perforin 1 (pore forming protein) 0.311377
PRSS21 protease, serine, 21 (testisin) 0.311377
NPY neuropeptide Y 0.310652
CP ceruloplasmin (ferroxidase) 0.310652
HBA1 hemoglobin, alpha 1 0.31029
RXFP4 relaxin/insulin-like family peptide receptor 4 0.31029
FBXW2 F-box and WD repeat domain containing 2 0.309928
SHE Src homology 2 domain containing E 0.309566
FLNA filamin A, alpha 0.308842
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.30848
CTSC cathepsin C 0.307757
CRTAM cytotoxic and regulatory T cell molecule 0.305948
BDKRB2 bradykinin receptor B2 0.305226
COMMD10 COMM domain containing 10 0.304864
MGST3 microsomal glutathione S-transferase 3 0.303781
RNASEH2A ribonuclease H2, subunit A 0.303059
MAP2K1 mitogen-activated protein kinase kinase 1 0.302698
MMP8 matrix metallopeptidase 8 0.301976
MMP7 matrix metallopeptidase 7 0.301976
TNS1 tensin 1 0.300533
TF transferrin 0.300173
HDAC1 histone deacetylase 1 0.298371
ADCY9 adenylate cyclase 9 0.298011
IL22 interleukin 22 0.298011
IL12B interleukin 12B 0.297651
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.293694
CPTP ceramide-1-phosphate transfer protein 0.293334
TJP1 tight junction protein 1 0.293334
PXYLP1 2-phosphoxylose phosphatase 1 0.292616
WDR46 WD repeat domain 46 0.292616
GRP gastrin-releasing peptide 0.291898
NPR1 natriuretic peptide receptor 1 0.291539
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.291539
SCP2 sterol carrier protein 2 0.290462
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.288668
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.287593
RGS5 regulator of G-protein signaling 5 0.286877
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.286519
PDE4C phosphodiesterase 4C, cAMP-specific 0.286519
HRH3 histamine receptor H3 0.28616
GCAT glycine C-acetyltransferase 0.285444
HLA-A major histocompatibility complex, class I, A 0.285086
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 0.284728
PTER phosphotriesterase related 0.284013
MAPK1 mitogen-activated protein kinase 1 0.283297
SPHK2 sphingosine kinase 2 0.283297
LUM lumican 0.282582
TPST1 tyrosylprotein sulfotransferase 1 0.282225
FGF10 fibroblast growth factor 10 0.281868
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.281868
DTD1 D-tyrosyl-tRNA deacylase 1 0.281868
VIPR1 vasoactive intestinal peptide receptor 1 0.28151
PRG3 proteoglycan 3 0.280439
KEAP1 kelch-like ECH-associated protein 1 0.279724
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.278297
F9 coagulation factor IX 0.277584
FGD1 FYVE, RhoGEF and PH domain containing 1 0.276514
XCL1 chemokine (C motif) ligand 1 0.275089
PRKCA protein kinase C, alpha 0.275089
C5 complement component 5 0.274732
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.274376
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.274376
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.274021
ITLN1 intelectin 1 (galactofuranose binding) 0.272953
ATF6B activating transcription factor 6 beta 0.272597
RXFP3 relaxin/insulin-like family peptide receptor 3 0.272597
LTB lymphotoxin beta (TNF superfamily, member 3) 0.272241
DEXI Dexi homolog (mouse) 0.271886
ICAM3 intercellular adhesion molecule 3 0.27153
EXOSC1 exosome component 1 0.270108
MED8 mediator complex subunit 8 0.270108
WASF3 WAS protein family, member 3 0.269398
CFP complement factor properdin 0.268332
TES testin LIM domain protein 0.268332
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 0.268332
TTC6 tetratricopeptide repeat domain 6 0.266558
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.266203
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.265494
GUCA2B guanylate cyclase activator 2B (uroguanylin) 0.265494
S100A9 S100 calcium binding protein A9 0.265494
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.26514
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.26514
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.264077
PI15 peptidase inhibitor 15 0.264077
CLCN6 chloride channel, voltage-sensitive 6 0.263368
TRIM26 tripartite motif containing 26 0.262306
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.261245
HYAL1 hyaluronoglucosaminidase 1 0.260891
FABP9 fatty acid binding protein 9, testis 0.260184
FANK1 fibronectin type III and ankyrin repeat domains 1 0.259477
DNASE1 deoxyribonuclease I 0.25877
USF2 upstream transcription factor 2, c-fos interacting 0.258064
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.257711
FGF1 fibroblast growth factor 1 (acidic) 0.256652
MED18 mediator complex subunit 18 0.256652
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 0.256299
IL7 interleukin 7 0.255946
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.255594
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.254888
AOAH acyloxyacyl hydrolase (neutrophil) 0.253831
ACTA1 actin, alpha 1, skeletal muscle 0.253479
ADORA2A adenosine A2a receptor 0.253479
MAPK9 mitogen-activated protein kinase 9 0.252774
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.252774
LST1 leukocyte specific transcript 1 0.251366
DPP8 dipeptidyl-peptidase 8 0.250311
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.248203
FXYD5 FXYD domain containing ion transport regulator 5 0.248203
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.247501
GUCY2C guanylate cyclase 2C 0.245396
CLTA clathrin, light chain A 0.244696
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.243995
CCR4 chemokine (C-C motif) receptor 4 0.243645
MFSD10 major facilitator superfamily domain containing 10 0.243295
F3 coagulation factor III (thromboplastin, tissue factor) 0.242245
NCEH1 neutral cholesterol ester hydrolase 1 0.241895
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.241546
PRMT2 protein arginine methyltransferase 2 0.241546
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.240847
MED6 mediator complex subunit 6 0.240148
TRIM37 tripartite motif containing 37 0.23945
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.238054
SEBOX SEBOX homeobox 0.237706
EPRS glutamyl-prolyl-tRNA synthetase 0.237706
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.237357
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.23666
DUOXA1 dual oxidase maturation factor 1 0.234225
IGLV2-8 immunoglobulin lambda variable 2-8 0.234225
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 0.233183
IFNL2 interferon, lambda 2 0.232489
NADK NAD kinase 0.231448
CREBBP CREB binding protein 0.230755
PNOC prepronociceptin 0.230409
VAMP7 vesicle-associated membrane protein 7 0.230409
IFNA5 interferon, alpha 5 0.230409
IFNL1 interferon, lambda 1 0.230409
HBE1 hemoglobin, epsilon 1 0.229716
CSN3 casein kappa 0.22937
TM6SF1 transmembrane 6 superfamily member 1 0.227642
MMP3 matrix metallopeptidase 3 0.227297
SSH1 slingshot protein phosphatase 1 0.227297
GSTM2 glutathione S-transferase mu 2 (muscle) 0.226952
SFSWAP splicing factor, suppressor of white-apricot family 0.226262
FLAD1 flavin adenine dinucleotide synthetase 1 0.225229
CLPS colipase, pancreatic 0.22454
PTPRD protein tyrosine phosphatase, receptor type, D 0.222136
CXCL6 chemokine (C-X-C motif) ligand 6 0.221793
DUOX1 dual oxidase 1 0.220424
CCL19 chemokine (C-C motif) ligand 19 0.220081
SPI1 Spi-1 proto-oncogene 0.219398
S1PR1 sphingosine-1-phosphate receptor 1 0.219057
MID1 midline 1 0.218374
MED22 mediator complex subunit 22 0.218374
NFE2L2 nuclear factor, erythroid 2-like 2 0.218034
APOA1 apolipoprotein A-I 0.217693
ASCL3 achaete-scute family bHLH transcription factor 3 0.217352
SPATS2L spermatogenesis associated, serine-rich 2-like 0.217012
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.216332
SRR serine racemase 0.216332
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.215992
TGM2 transglutaminase 2 0.215992
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.215653
SFTA3 surfactant associated 3 0.214636
POFUT1 protein O-fucosyltransferase 1 0.214297
STAG2 stromal antigen 2 0.214297
CLEC6A C-type lectin domain family 6, member A 0.213959
LATS2 large tumor suppressor kinase 2 0.213283
C4A complement component 4A (Rodgers blood group) 0.212608
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.212608
GCG glucagon 0.212608
SYNPO2 synaptopodin 2 0.211934
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 0.211934
MIR187 microRNA 187 0.211597
GNAS GNAS complex locus 0.211597
ACPP acid phosphatase, prostate 0.211597
MUC4 mucin 4, cell surface associated 0.209918
TPSG1 tryptase gamma 1 0.208579
ICAM2 intercellular adhesion molecule 2 0.208579
SP6 Sp6 transcription factor 0.205916
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.205916
DOCK11 dedicator of cytokinesis 11 0.205254
NKX1-1 NK1 homeobox 1 0.204923
LBP lipopolysaccharide binding protein 0.204593
SFTPC surfactant protein C 0.204263
CLCN3 chloride channel, voltage-sensitive 3 0.203604
ADRA1B adrenoceptor alpha 1B 0.203275
DUOX2 dual oxidase 2 0.20229
TMEM11 transmembrane protein 11 0.20229
DEFB4A defensin, beta 4A 0.201962
WISP1 WNT1 inducible signaling pathway protein 1 0.201635
IL12RB1 interleukin 12 receptor, beta 1 0.201635
NCAM1 neural cell adhesion molecule 1 0.200331
ELP5 elongator acetyltransferase complex subunit 5 0.200006
RHO rhodopsin 0.200006
ZNF101 zinc finger protein 101 0.200006
PDGFB platelet-derived growth factor beta polypeptide 0.199681
GPR17 G protein-coupled receptor 17 0.199681
NOTCH1 notch 1 0.199356
RGS2 regulator of G-protein signaling 2 0.199033
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.199033
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.199033
GGT1 gamma-glutamyltransferase 1 0.199033
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.198709
REN renin 0.197742
LY86 lymphocyte antigen 86 0.19742
PIDD1 p53-induced death domain protein 1 0.197099
OSM oncostatin M 0.19582
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.19582
SIK1 salt-inducible kinase 1 0.19582
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.194865
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.194865
NPAS3 neuronal PAS domain protein 3 0.193285
EDNRB endothelin receptor type B 0.192657
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.192657
SARS seryl-tRNA synthetase 0.192031
CXCR4 chemokine (C-X-C motif) receptor 4 0.191719
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.191408
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.190168
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.190168
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.189551
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.188632
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.188632
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.188022
EOMES eomesodermin 0.187113
TBC1D23 TBC1 domain family, member 23 0.187113
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.187113
TP63 tumor protein p63 0.186811
THEM4 thioesterase superfamily member 4 0.186811
NPW neuropeptide W 0.186811
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.18621
GATA2 GATA binding protein 2 0.18591
IRAK4 interleukin-1 receptor-associated kinase 4 0.185612
AVP arginine vasopressin 0.185313
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.185016
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.184128
PRKD1 protein kinase D1 0.183835
ACAA1 acetyl-CoA acyltransferase 1 0.183835
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.183835
RORC RAR-related orphan receptor C 0.182957
SCIN scinderin 0.182957
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 0.182957
CASS4 Cas scaffolding protein family member 4 0.182375
FILIP1 filamin A interacting protein 1 0.182375
ATRN attractin 0.182375
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.182086
AURKAIP1 aurora kinase A interacting protein 1 0.181798
SEC14L3 SEC14-like 3 (S. cerevisiae) 0.18151
PLXND1 plexin D1 0.18151
MYO5C myosin VC 0.18151
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.180937
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.180367
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.17952
CXCR5 chemokine (C-X-C motif) receptor 5 0.17952
NDFIP2 Nedd4 family interacting protein 2 0.17952
ADRA1D adrenoceptor alpha 1D 0.17952
RBP7 retinol binding protein 7, cellular 0.179239
CFL1 cofilin 1 (non-muscle) 0.179239
LPAR2 lysophosphatidic acid receptor 2 0.178403
CCL14 chemokine (C-C motif) ligand 14 0.177851
TFRC transferrin receptor 0.177576
VIMP VCP-interacting membrane selenoprotein 0.177576
CCL21 chemokine (C-C motif) ligand 21 0.176485
TXK TXK tyrosine kinase 0.176215
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.175146
POMP proteasome maturation protein 0.175146
IGFBP3 insulin-like growth factor binding protein 3 0.174881
TGFBR1 transforming growth factor, beta receptor 1 0.174881
FLT1 fms-related tyrosine kinase 1 0.174617
PIGR polymeric immunoglobulin receptor 0.174354
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.173832
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.173314
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.173057
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.172799
ENO1 enolase 1, (alpha) 0.172038
IL22RA1 interleukin 22 receptor, alpha 1 0.172038
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 0.171535
COL22A1 collagen, type XXII, alpha 1 0.170789
RGS7BP regulator of G-protein signaling 7 binding protein 0.170544
TYK2 tyrosine kinase 2 0.170299
C9ORF24 chromosome 9 open reading frame 24 0.169571
PLAUR plasminogen activator, urokinase receptor 0.169571
MUC1 mucin 1, cell surface associated 0.16933
TMPRSS11D transmembrane protease, serine 11D 0.16933
SPRED1 sprouty-related, EVH1 domain containing 1 0.169091
FST follistatin 0.169091
ELF5 E74-like factor 5 (ets domain transcription factor) 0.168854
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.167452
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.167452
TAC4 tachykinin 4 (hemokinin) 0.166319
CMKLR1 chemerin chemokine-like receptor 1 0.166095
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.165874
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.165874
MIR21 microRNA 21 0.165874
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.165655
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.165435
ADIPOR1 adiponectin receptor 1 0.165435
ZFYVE9 zinc finger, FYVE domain containing 9 0.165435
TAS2R14 taste receptor, type 2, member 14 0.165001
CPE carboxypeptidase E 0.164786
TLE4 transducin-like enhancer of split 4 0.164786
DPF2 D4, zinc and double PHD fingers family 2 0.164359
LEPR leptin receptor 0.164149
COX5A cytochrome c oxidase subunit Va 0.163938
DEGS1 delta(4)-desaturase, sphingolipid 1 0.163729
KCNK15 potassium channel, two pore domain subfamily K, member 15 0.163317
AADACL3 arylacetamide deacetylase-like 3 0.163317
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.163317
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.163111
HYAL2 hyaluronoglucosaminidase 2 0.163111
HIST1H4C histone cluster 1, H4c 0.162908
HIST1H4B histone cluster 1, H4b 0.162908
HIST1H4A histone cluster 1, H4a 0.162908
HIST1H4F histone cluster 1, H4f 0.162908
HIST1H4E histone cluster 1, H4e 0.162908
HIST1H4D histone cluster 1, H4d 0.162908
HIST1H4K histone cluster 1, H4k 0.162908
HIST1H4J histone cluster 1, H4j 0.162908
HIST1H4I histone cluster 1, H4i 0.162908
HIST1H4H histone cluster 1, H4h 0.162908
HIST2H4B histone cluster 2, H4b 0.162908
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.162505
HIST2H4A histone cluster 2, H4a 0.162505
AICDA activation-induced cytidine deaminase 0.162109
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.161716
HIST1H4L histone cluster 1, H4l 0.161523
HIST4H4 histone cluster 4, H4 0.161523
DEFA1B defensin, alpha 1B 0.161331
DEFA1 defensin, alpha 1 0.161331
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.161139
CST4 cystatin S 0.161139
FBXO17 F-box protein 17 0.160761
RPIA ribose 5-phosphate isomerase A 0.160761
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.160574
MED14 mediator complex subunit 14 0.160203
CTH cystathionine gamma-lyase 0.160021
CTRL chymotrypsin-like 0.159838
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.159658
C1QBP complement component 1, q subcomponent binding protein 0.159302
HRAS Harvey rat sarcoma viral oncogene homolog 0.158778
PRDX1 peroxiredoxin 1 0.158434
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.158266
PTGFR prostaglandin F receptor (FP) 0.158097
RND1 Rho family GTPase 1 0.143562
ADAM2 ADAM metallopeptidase domain 2 0.143254
RING1 ring finger protein 1 0.142835
STAB2 stabilin 2 0.139819
AMY2A amylase, alpha 2A (pancreatic) 0.139383
SYNE2 spectrin repeat containing, nuclear envelope 2 0.138622
WDFY2 WD repeat and FYVE domain containing 2 0.138355
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.138285
IGHV3-9 immunoglobulin heavy variable 3-9 0.137728
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.137485
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.137476
GZMK granzyme K (granzyme 3; tryptase II) 0.137458
A1BG alpha-1-B glycoprotein 0.137431
YTHDC1 YTH domain containing 1 0.137431
PTPRE protein tyrosine phosphatase, receptor type, E 0.136388
CPB2 carboxypeptidase B2 (plasma) 0.136337
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.13577
GIMAP4 GTPase, IMAP family member 4 0.13544
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 0.135206
P3H2 prolyl 3-hydroxylase 2 0.134829
ABR active BCR-related 0.13373
IFI6 interferon, alpha-inducible protein 6 0.132751
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 0.132545
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.132529
FCAR Fc fragment of IgA receptor 0.132481
EPCAM epithelial cell adhesion molecule 0.13207
RHOA ras homolog family member A 0.13166
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.131269
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.131031
NVL nuclear VCP-like 0.130806
RIPK2 receptor-interacting serine-threonine kinase 2 0.130712
IL10RA interleukin 10 receptor, alpha 0.130499
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.130264
CHML choroideremia-like (Rab escort protein 2) 0.130264
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.130224
TRIM46 tripartite motif containing 46 0.130164
KRT18 keratin 18, type I 0.130124
LMTK2 lemur tyrosine kinase 2 0.130024
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.129859
CYGB cytoglobin 0.12959
PGAP3 post-GPI attachment to proteins 3 0.129006
GIF gastric intrinsic factor (vitamin B synthesis) 0.128829
NFIL3 nuclear factor, interleukin 3 regulated 0.12823
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.127229
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.125814
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.125643
UNC119 unc-119 homolog (C. elegans) 0.125241
CD59 CD59 molecule, complement regulatory protein 0.125123
PTPRC protein tyrosine phosphatase, receptor type, C 0.125064
SNX9 sorting nexin 9 0.124887
NOX3 NADPH oxidase 3 0.124707
F8 coagulation factor VIII, procoagulant component 0.123933
PDE7B phosphodiesterase 7B 0.123744
PLAC1 placenta-specific 1 0.123517
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.123354
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.123256
DOCK1 dedicator of cytokinesis 1 0.122754
PFDN4 prefoldin subunit 4 0.122203
PARP14 poly (ADP-ribose) polymerase family, member 14 0.122064
CLEC7A C-type lectin domain family 7, member A 0.121455
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.121199
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.121199
CD226 CD226 molecule 0.120901
DLL4 delta-like 4 (Drosophila) 0.120486
KCNIP4 Kv channel interacting protein 4 0.119905
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.119866
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.119826
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.119145
ZBTB32 zinc finger and BTB domain containing 32 0.118775
FER fer (fps/fes related) tyrosine kinase 0.118315
VIPR2 vasoactive intestinal peptide receptor 2 0.118315
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.118272
ITGAD integrin, alpha D 0.11823
USO1 USO1 vesicle transport factor 0.117804