apoptotic body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A fragment containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. (Gene Ontology, GO_0097189)
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Genes

137 proteins co-occuring with the apoptotic body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.22692
BAX BCL2-associated X protein 1.88555
DNTT DNA nucleotidylexotransferase 1.84088
ANXA5 annexin A5 1.78058
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.56446
TP53 tumor protein p53 1.51356
PARP1 poly (ADP-ribose) polymerase 1 1.37133
TMEM132D transmembrane protein 132D 1.34065
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.21014
BCL2 B-cell CLL/lymphoma 2 1.19828
FASLG Fas ligand (TNF superfamily, member 6) 1.10715
BCL2L1 BCL2-like 1 1.05993
PCNA proliferating cell nuclear antigen 1.003
CARD17 caspase recruitment domain family, member 17 0.968884
FAM105A family with sequence similarity 105, member A 0.967437
LCN9 lipocalin 9 0.967437
TNF tumor necrosis factor 0.933601
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.814405
TMEM59L transmembrane protein 59-like 0.777298
JUN jun proto-oncogene 0.715902
BIRC5 baculoviral IAP repeat containing 5 0.686827
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.678543
CD4 CD4 molecule 0.648721
SP2 Sp2 transcription factor 0.643144
CLU clusterin 0.636295
CCNB1 cyclin B1 0.611625
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.57008
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.563432
TGFB1 transforming growth factor, beta 1 0.563432
SARAF store-operated calcium entry-associated regulatory factor 0.551012
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.544411
TAOK2 TAO kinase 2 0.539883
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.530028
IL1B interleukin 1, beta 0.52675
TTC30B tetratricopeptide repeat domain 30B 0.525522
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 0.525522
IGKV3-20 immunoglobulin kappa variable 3-20 0.525522
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.5149
FOS FBJ murine osteosarcoma viral oncogene homolog 0.511233
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.507977
CD68 CD68 molecule 0.50107
APOH apolipoprotein H (beta-2-glycoprotein I) 0.490944
TAOK1 TAO kinase 1 0.485693
JMJD6 jumonji domain containing 6 0.468802
NCAM1 neural cell adhesion molecule 1 0.461599
TMEM123 transmembrane protein 123 0.458803
MGP matrix Gla protein 0.450438
CAT catalase 0.435775
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.431435
OTP orthopedia homeobox 0.429859
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.416902
MIR197 microRNA 197 0.404804
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.390068
HIST1H2BG histone cluster 1, H2bg 0.371216
HIST1H2BI histone cluster 1, H2bi 0.371216
HIST1H2BE histone cluster 1, H2be 0.371216
MERTK MER proto-oncogene, tyrosine kinase 0.370067
BIRC7 baculoviral IAP repeat containing 7 0.369301
BECN1 beclin 1, autophagy related 0.358609
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.356324
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.348725
CD40LG CD40 ligand 0.345692
HRAS Harvey rat sarcoma viral oncogene homolog 0.341907
HNF1B HNF1 homeobox B 0.339639
MIR223 microRNA 223 0.337751
APAF1 apoptotic peptidase activating factor 1 0.332848
MFGE8 milk fat globule-EGF factor 8 protein 0.332848
KRT20 keratin 20, type I 0.327956
BAD BCL2-associated agonist of cell death 0.327205
MAPK8 mitogen-activated protein kinase 8 0.326453
AHSG alpha-2-HS-glycoprotein 0.324951
STYK1 serine/threonine/tyrosine kinase 1 0.32345
GDF15 growth differentiation factor 15 0.317082
IL2 interleukin 2 0.317082
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.316708
ASGR2 asialoglycoprotein receptor 2 0.313718
ASGR1 asialoglycoprotein receptor 1 0.312597
PRF1 perforin 1 (pore forming protein) 0.304771
CCND1 cyclin D1 0.303655
HECA headcase homolog (Drosophila) 0.295489
HSPA4 heat shock 70kDa protein 4 0.292157
THOC7 THO complex 7 0.286614
ATG7 autophagy related 7 0.283295
GSTA3 glutathione S-transferase alpha 3 0.27998
GSTA2 glutathione S-transferase alpha 2 0.278509
GSTA4 glutathione S-transferase alpha 4 0.278509
MIR191 microRNA 191 0.277038
GSTA1 glutathione S-transferase alpha 1 0.276304
MKI67 marker of proliferation Ki-67 0.266042
ALOX12 arachidonate 12-lipoxygenase 0.258745
PGM1 phosphoglucomutase 1 0.256561
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.25438
TROVE2 TROVE domain family, member 2 0.253653
ONECUT3 one cut homeobox 3 0.24894
LYAR Ly1 antibody reactive 0.248216
SOD2 superoxide dismutase 2, mitochondrial 0.247854
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.243158
TDGF1 teratocarcinoma-derived growth factor 1 0.241716
NUMA1 nuclear mitotic apparatus protein 1 0.23776
CD5 CD5 molecule 0.235966
CCL23 chemokine (C-C motif) ligand 23 0.228108
TRIM21 tripartite motif containing 21 0.227752
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.227752
DIABLO diablo, IAP-binding mitochondrial protein 0.223497
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.218212
BOK BCL2-related ovarian killer 0.214366
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.212974
TSPO translocator protein (18kDa) 0.212627
IL6 interleukin 6 0.211587
TYMS thymidylate synthetase 0.203022
ALPPL2 alkaline phosphatase, placental-like 2 0.202346
ALPL alkaline phosphatase, liver/bone/kidney 0.202009
ALPP alkaline phosphatase, placental 0.201672
PLXNC1 plexin C1 0.200999
VEGFA vascular endothelial growth factor A 0.198325
CIAO1 cytosolic iron-sulfur assembly component 1 0.195025
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.194698
SCARB2 scavenger receptor class B, member 2 0.193394
SDPR serum deprivation response 0.192423
IGF1 insulin-like growth factor 1 (somatomedin C) 0.1921
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.18516
EGFR epidermal growth factor receptor 0.183631
HBA1 hemoglobin, alpha 1 0.183025
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.183025
SIGLEC14 sialic acid binding Ig-like lectin 14 0.181524
HBA2 hemoglobin, alpha 2 0.178588
CD36 CD36 molecule (thrombospondin receptor) 0.17687
GAST gastrin 0.175188
SEBOX SEBOX homeobox 0.171673
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.170114
IL11 interleukin 11 0.165231
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.1632
CSPP1 centrosome and spindle pole associated protein 1 0.16298
H2AFX H2A histone family, member X 0.16233
RPS29 ribosomal protein S29 0.158882
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.158315
HLA-B major histocompatibility complex, class I, B 0.156513