apoplexy; stroke Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cardiovascular (Genetic Association Database)
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Genes

38 genes associated with the disease apoplexy; stroke in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ANGPT1 angiopoietin 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
BDNF brain-derived neurotrophic factor
CETP cholesteryl ester transfer protein, plasma
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
GP1BA glycoprotein Ib (platelet), alpha polypeptide
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL6 interleukin 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LPL lipoprotein lipase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NOS3 nitric oxide synthase 3 (endothelial cell)
PDE4D phosphodiesterase 4D, cAMP-specific
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
XK X-linked Kx blood group
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1