apigenin-4578 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the apigenin-4578 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ALOX5 arachidonate 5-lipoxygenase
ALPPL2 alkaline phosphatase, placental-like 2
AOC3 amine oxidase, copper containing 3
ARHGAP28 Rho GTPase activating protein 28
ATXN7L1 ataxin 7-like 1
C11ORF1 chromosome 11 open reading frame 1
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2CD2L C2CD2-like
CABP2 calcium binding protein 2
CADM3 cell adhesion molecule 3
CALML3 calmodulin-like 3
CCDC186 coiled-coil domain containing 186
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CELP carboxyl ester lipase pseudogene
CLCN7 chloride channel, voltage-sensitive 7
CLUL1 clusterin-like 1 (retinal)
CST4 cystatin S
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTAG2 cancer/testis antigen 2
CTNND2 catenin (cadherin-associated protein), delta 2
CXORF21 chromosome X open reading frame 21
DEFB4A defensin, beta 4A
DMP1 dentin matrix acidic phosphoprotein 1
DNAAF1 dynein, axonemal, assembly factor 1
DTNB dystrobrevin, beta
EPYC epiphycan
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFR4 fibroblast growth factor receptor 4
FILIP1L filamin A interacting protein 1-like
FLT4 fms-related tyrosine kinase 4
GAS7 growth arrest-specific 7
HAP1 huntingtin-associated protein 1
HBS1L HBS1-like translational GTPase
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPCA hippocalcin
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
HYAL1 hyaluronoglucosaminidase 1
IGHA1 immunoglobulin heavy constant alpha 1
IL1RN interleukin 1 receptor antagonist
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1045 KIAA1045
KRT7 keratin 7, type II
LEFTY1 left-right determination factor 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC157562 uncharacterized LOC157562
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTMR3 myotubularin related protein 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP2L2 NEDD4 binding protein 2-like 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEK9 NIMA-related kinase 9
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOTCH3 notch 3
NUP88 nucleoporin 88kDa
PAQR6 progestin and adipoQ receptor family member VI
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POPDC2 popeye domain containing 2
POU6F2 POU class 6 homeobox 2
PRDM14 PR domain containing 14
PRM2 protamine 2
PROL1 proline rich, lacrimal 1
PRX periaxin
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB6A RAB6A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS5 regulator of G-protein signaling 5
SCN10A sodium channel, voltage gated, type X alpha subunit
SELL selectin L
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHANK1 SH3 and multiple ankyrin repeat domains 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX30 SRY (sex determining region Y)-box 30
SPINK5 serine peptidase inhibitor, Kazal type 5
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAAR5 trace amine associated receptor 5
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP10L t-complex 10-like
TEF thyrotrophic embryonic factor
TINAGL1 tubulointerstitial nephritis antigen-like 1
TRIO trio Rho guanine nucleotide exchange factor
UBA7 ubiquitin-like modifier activating enzyme 7
WDR59 WD repeat domain 59
ZNF268 zinc finger protein 268
ZNF44 zinc finger protein 44
ZNF639 zinc finger protein 639
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMCX5 armadillo repeat containing, X-linked 5
AZI2 5-azacytidine induced 2
BBS7 Bardet-Biedl syndrome 7
C1ORF115 chromosome 1 open reading frame 115
C1ORF27 chromosome 1 open reading frame 27
C1QTNF1 C1q and tumor necrosis factor related protein 1
C9ORF91 chromosome 9 open reading frame 91
CD83 CD83 molecule
CDC37L1 cell division cycle 37-like 1
CHMP7 charged multivesicular body protein 7
CLASP1 cytoplasmic linker associated protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTAGE9 CTAGE family, member 9
CUTC cutC copper transporter
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DAAM1 dishevelled associated activator of morphogenesis 1
DCAF16 DDB1 and CUL4 associated factor 16
EFNA3 ephrin-A3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERCC2 excision repair cross-complementation group 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
GJC1 gap junction protein, gamma 1, 45kDa
GPR87 G protein-coupled receptor 87
GRAMD3 GRAM domain containing 3
HLX H2.0-like homeobox
HPSE heparanase
IFT46 intraflagellar transport 46
IL1B interleukin 1, beta
ING3 inhibitor of growth family, member 3
ISOC1 isochorismatase domain containing 1
JMJD4 jumonji domain containing 4
KCTD7 potassium channel tetramerization domain containing 7
KIF15 kinesin family member 15
LOC730101 uncharacterized LOC730101
LPAR6 lysophosphatidic acid receptor 6
MAST3 microtubule associated serine/threonine kinase 3
MEIS1 Meis homeobox 1
MEPCE methylphosphate capping enzyme
MITF microphthalmia-associated transcription factor
MSL1 male-specific lethal 1 homolog (Drosophila)
MTMR11 myotubularin related protein 11
NDRG4 NDRG family member 4
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NR3C2 nuclear receptor subfamily 3, group C, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PALMD palmdelphin
PARP16 poly (ADP-ribose) polymerase family, member 16
PDZD2 PDZ domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PIAS3 protein inhibitor of activated STAT, 3
PLK2 polo-like kinase 2
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PTX3 pentraxin 3, long
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBL1 retinoblastoma-like 1
RBM38 RNA binding motif protein 38
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHOBTB1 Rho-related BTB domain containing 1
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD8 SET domain containing (lysine methyltransferase) 8
SGMS1 sphingomyelin synthase 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC35A5 solute carrier family 35, member A5
SLC46A3 solute carrier family 46, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPC25 SPC25, NDC80 kinetochore complex component
ST5 suppression of tumorigenicity 5
STAC SH3 and cysteine rich domain
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D19 TBC1 domain family, member 19
TBX3 T-box 3
TMEM2 transmembrane protein 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TSPAN12 tetraspanin 12
TTC17 tetratricopeptide repeat domain 17
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3C tubulin, alpha 3c
ZBTB10 zinc finger and BTB domain containing 10
ZNF165 zinc finger protein 165
ZNF248 zinc finger protein 248
ZNF33B zinc finger protein 33B
ZNF365 zinc finger protein 365
ZNF408 zinc finger protein 408
ZNF552 zinc finger protein 552
ZNF586 zinc finger protein 586