apical plasma membrane Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description The region of the plasma membrane located at the apical end of the cell. (Gene Ontology, GO_0016324)
External Link http://amigo.geneontology.org/amigo/term/GO:0016324
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Genes

253 proteins localized to the apical plasma membrane cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACY3 aminoacylase 3
ADAM17 ADAM metallopeptidase domain 17
ADGRG2 adhesion G protein-coupled receptor G2
ADRB2 adrenoceptor beta 2, surface
AJAP1 adherens junctions associated protein 1
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AMN amnion associated transmembrane protein
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
ANK2 ankyrin 2, neuronal
ANO1 anoctamin 1, calcium activated chloride channel
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AQP1 aquaporin 1 (Colton blood group)
AQP2 aquaporin 2 (collecting duct)
AQP5 aquaporin 5
AQP6 aquaporin 6, kidney specific
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BST2 bone marrow stromal cell antigen 2
CA4 carbonic anhydrase IV
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CD300LG CD300 molecule-like family member g
CD34 CD34 molecule
CD9 CD9 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDHR2 cadherin-related family member 2
CFAP126 cilia and flagella associated protein 126
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIB1 calcium and integrin binding 1 (calmyrin)
CLCA4 chloride channel accessory 4
CLCN3 chloride channel, voltage-sensitive 3
CLDN1 claudin 1
CLDN4 claudin 4
CLDND1 claudin domain containing 1
CNTFR ciliary neurotrophic factor receptor
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRB3 crumbs family member 3
CSPG4 chondroitin sulfate proteoglycan 4
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYBA cytochrome b-245, alpha polypeptide
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDR2 discoidin domain receptor tyrosine kinase 2
DPEP1 dipeptidase 1 (renal)
DPP4 dipeptidyl-peptidase 4
DSG1 desmoglein 1
DSG2 desmoglein 2
DSTYK dual serine/threonine and tyrosine protein kinase
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
EGFR epidermal growth factor receptor
EMP2 epithelial membrane protein 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPCAM epithelial cell adhesion molecule
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EZR ezrin
F2RL2 coagulation factor II (thrombin) receptor-like 2
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FZD3 frizzled class receptor 3
FZD6 frizzled class receptor 6
GIF gastric intrinsic factor (vitamin B synthesis)
GJA1 gap junction protein, alpha 1, 43kDa
GJB6 gap junction protein, beta 6, 30kDa
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GP2 glycoprotein 2 (zymogen granule membrane)
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GPR143 G protein-coupled receptor 143
HAX1 HCLS1 associated protein X-1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HYAL2 hyaluronoglucosaminidase 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL6R interleukin 6 receptor
INADL InaD-like (Drosophila)
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1919 KIAA1919
KNCN kinocilin
LCT lactase
LHFPL5 lipoma HMGIC fusion partner-like 5
LRP2 low density lipoprotein receptor-related protein 2
LZTS1 leucine zipper, putative tumor suppressor 1
MAL mal, T-cell differentiation protein
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MARVELD2 MARVEL domain containing 2
MFRP membrane frizzled-related protein
MGAM maltase-glucoamylase
MIP major intrinsic protein of lens fiber
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MPDZ multiple PDZ domain protein
MREG melanoregulin
MSN moesin
MTCL1 microtubule crosslinking factor 1
MTDH metadherin
MUC1 mucin 1, cell surface associated
MUC13 mucin 13, cell surface associated
MUC17 mucin 17, cell surface associated
MUC20 mucin 20, cell surface associated
MYO1A myosin IA
MYO7A myosin VIIA
MYO7B myosin VIIB
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NOD1 nucleotide-binding oligomerization domain containing 1
NOX4 NADPH oxidase 4
NPC1L1 NPC1-like 1
OCLN occludin
OSMR oncostatin M receptor
OTOA otoancorin
OTOG otogelin
OXTR oxytocin receptor
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPN podoplanin
PDZK1 PDZ domain containing 1
PFKM phosphofructokinase, muscle
PIP prolactin-induced protein
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLB1 phospholipase B1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLET1 placenta expressed transcript 1
PODXL podocalyxin-like
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKG2 protein kinase, cGMP-dependent, type II
PROM1 prominin 1
PROM2 prominin 2
PSEN1 presenilin 1
PSEN2 presenilin 2
PTH1R parathyroid hormone 1 receptor
PTK2 protein tyrosine kinase 2
PTPRO protein tyrosine phosphatase, receptor type, O
RAB17 RAB17, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RHCG Rh family, C glycoprotein
S100G S100 calcium binding protein G
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEPT7 septin 7
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHROOM2 shroom family member 2
SHROOM3 shroom family member 3
SHROOM4 shroom family member 4
SI sucrase-isomaltase (alpha-glucosidase)
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC17A3 solute carrier family 17 (organic anion transporter), member 3
SLC17A4 solute carrier family 17, member 4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLC22A18 solute carrier family 22, member 18
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC52A3 solute carrier family 52 (riboflavin transporter), member 3
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
SPTBN2 spectrin, beta, non-erythrocytic 2
STC1 stanniocalcin 1
STK26 serine/threonine protein kinase 26
STK39 serine threonine kinase 39
STX3 syntaxin 3
STXBP3 syntaxin binding protein 3
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TF transferrin
THY1 Thy-1 cell surface antigen
TJP1 tight junction protein 1
TJP3 tight junction protein 3
TLR9 toll-like receptor 9
TMEM114 transmembrane protein 114
TMEM235 transmembrane protein 235
TMEM30A transmembrane protein 30A
TNIK TRAF2 and NCK interacting kinase
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UMOD uromodulin
UPK1A uroplakin 1A
UPK1B uroplakin 1B
UPK2 uroplakin 2
UPK3A uroplakin 3A
USH2A Usher syndrome 2A (autosomal recessive, mild)
VAMP3 vesicle-associated membrane protein 3
VANGL2 VANGL planar cell polarity protein 2
WDPCP WD repeat containing planar cell polarity effector