apical plasma membrane Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The region of the plasma membrane located at the apical end of the cell. (Gene Ontology, GO_0016324)
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Genes

242 proteins co-occuring with the apical plasma membrane cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
AQP2 aquaporin 2 (collecting duct) 2.32721
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.63658
AQP5 aquaporin 5 1.5943
STX3 syntaxin 3 1.57989
AVP arginine vasopressin 1.46608
DNAH8 dynein, axonemal, heavy chain 8 1.37299
AQP3 aquaporin 3 (Gill blood group) 1.29478
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.12552
AQP7 aquaporin 7 1.0564
TG thyroglobulin 1.05287
STX4 syntaxin 4 1.04984
GP2 glycoprotein 2 (zymogen granule membrane) 1.02879
AQP4 aquaporin 4 1.01883
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.96503
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.95831
DUOXA2 dual oxidase maturation factor 2 0.95831
STX2 syntaxin 2 0.951142
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.944482
AQP6 aquaporin 6, kidney specific 0.944007
EZR ezrin 0.935488
AQP1 aquaporin 1 (Colton blood group) 0.931245
NSF N-ethylmaleimide-sensitive factor 0.915309
STXBP2 syntaxin binding protein 2 0.909251
FTL ferritin, light polypeptide 0.899036
FTH1 ferritin, heavy polypeptide 1 0.89672
RHCG Rh family, C glycoprotein 0.85342
LRP2 low density lipoprotein receptor-related protein 2 0.836892
AQP10 aquaporin 10 0.831384
UPK1B uroplakin 1B 0.830925
ANPEP alanyl (membrane) aminopeptidase 0.830466
SNAP23 synaptosomal-associated protein, 23kDa 0.825877
RAB11A RAB11A, member RAS oncogene family 0.809359
VAMP8 vesicle-associated membrane protein 8 0.793771
PIGR polymeric immunoglobulin receptor 0.786444
COX5A cytochrome c oxidase subunit Va 0.75317
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.719906
UPK1A uroplakin 1A 0.71768
UPK3A uroplakin 3A 0.710136
CA4 carbonic anhydrase IV 0.705714
UPK2 uroplakin 2 0.703949
AVPR2 arginine vasopressin receptor 2 0.699983
USP10 ubiquitin specific peptidase 10 0.69427
DPP4 dipeptidyl-peptidase 4 0.69164
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.681591
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.674196
AQP11 aquaporin 11 0.662935
ALPPL2 alkaline phosphatase, placental-like 2 0.661208
ALPP alkaline phosphatase, placental 0.661208
ALPL alkaline phosphatase, liver/bone/kidney 0.660776
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.653019
AQP12A aquaporin 12A 0.652159
DCHS1 dachsous cadherin-related 1 0.650869
AQP8 aquaporin 8 0.647003
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.646574
RAB3D RAB3D, member RAS oncogene family 0.644001
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 0.636295
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.632878
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.632878
CYS1 cystin 1 0.629465
ANXA13 annexin A13 0.626483
PRSS8 protease, serine, 8 0.61883
TROAP trophinin associated protein 0.613742
FLOT2 flotillin 2 0.612895
DUOX2 dual oxidase 2 0.604017
TPO thyroid peroxidase 0.604017
RHBG Rh family, B glycoprotein (gene/pseudogene) 0.600644
VAMP3 vesicle-associated membrane protein 3 0.598117
STXBP3 syntaxin binding protein 3 0.589295
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.588456
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.586361
CA2 carbonic anhydrase II 0.583012
HGFAC HGF activator 0.577581
MFGE8 milk fat globule-EGF factor 8 protein 0.576329
DUOX1 dual oxidase 1 0.575912
DUOXA1 dual oxidase maturation factor 1 0.570496
TJP1 tight junction protein 1 0.57008
RAB27A RAB27A, member RAS oncogene family 0.565923
ATP11A ATPase, class VI, type 11A 0.5597
CD79A CD79a molecule, immunoglobulin-associated alpha 0.5568
MYO5B myosin VB 0.552251
SGK1 serum/glucocorticoid regulated kinase 1 0.541529
MUC1 mucin 1, cell surface associated 0.535772
SLCO1A2 solute carrier organic anion transporter family, member 1A2 0.53413
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.521023
CCK cholecystokinin 0.518165
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.510011
GAST gastrin 0.509197
AGTR2 angiotensin II receptor, type 2 0.50757
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.507163
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.504724
HMBS hydroxymethylbilane synthase 0.503912
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.492561
SYTL4 synaptotagmin-like 4 0.489731
KRT20 keratin 20, type I 0.477233
RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.473215
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.466799
KLHL3 kelch-like family member 3 0.456809
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.454418
PTPRO protein tyrosine phosphatase, receptor type, O 0.452825
ARF6 ADP-ribosylation factor 6 0.446465
RAB27B RAB27B, member RAS oncogene family 0.446465
MIP major intrinsic protein of lens fiber 0.445275
STX1A syntaxin 1A (brain) 0.442896
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.442104
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.439333
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.432224
ADCY2 adenylate cyclase 2 (brain) 0.422782
SLC22A20 solute carrier family 22, member 20 0.417685
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.412992
MUC20 mucin 20, cell surface associated 0.409479
MYO5C myosin VC 0.40714
TALDO1 transaldolase 1 0.40675
NT5E 5'-nucleotidase, ecto (CD73) 0.404026
CD164 CD164 molecule, sialomucin 0.401693
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.397423
TRO trophinin 0.397423
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.393936
LAP3 leucine aminopeptidase 3 0.389682
RHCE Rh blood group, CcEe antigens 0.384665
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 0.381584
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.378122
HYI hydroxypyruvate isomerase (putative) 0.37697
LPO lactoperoxidase 0.373899
MYOF myoferlin 0.367006
PDZK1 PDZ domain containing 1 0.366241
MAL mal, T-cell differentiation protein 0.365477
HSPA8 heat shock 70kDa protein 8 0.363185
ANXA10 annexin A10 0.361659
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.360515
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.35899
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.356705
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.355563
ZNF77 zinc finger protein 77 0.355183
ACPP acid phosphatase, prostate 0.354802
PROM1 prominin 1 0.353662
CLMN calmin (calponin-like, transmembrane) 0.352901
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.346829
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.345692
MME membrane metallo-endopeptidase 0.343421
ANXA2 annexin A2 0.341907
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.338128
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.335487
SLC22A10 solute carrier family 22, member 10 0.333979
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.328332
TF transferrin 0.325327
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.324576
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.32195
SI sucrase-isomaltase (alpha-glucosidase) 0.321201
MSN moesin 0.320077
UMOD uromodulin 0.317456
INSM1 insulinoma-associated 1 0.315212
SLC39A1 solute carrier family 39 (zinc transporter), member 1 0.314465
RAP2B RAP2B, member of RAS oncogene family 0.310732
GIF gastric intrinsic factor (vitamin B synthesis) 0.30626
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.30626
SAR1A secretion associated, Ras related GTPase 1A 0.304027
ARF3 ADP-ribosylation factor 3 0.303655
RAB1B RAB1B, member RAS oncogene family 0.300682
SNX18 sorting nexin 18 0.296972
INADL InaD-like (Drosophila) 0.294007
ALB albumin 0.291047
FAT4 FAT atypical cadherin 4 0.290678
RHD Rh blood group, D antigen 0.288829
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.286245
RDX radixin 0.283663
OSGEP O-sialoglycoprotein endopeptidase 0.283295
NRG2 neuregulin 2 0.278877
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 0.278141
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.277406
TBC1D10A TBC1 domain family, member 10A 0.276671
TMEM38A transmembrane protein 38A 0.275936
NRG3 neuregulin 3 0.275936
STX6 syntaxin 6 0.275569
STX7 syntaxin 7 0.275202
CSN1S1 casein alpha s1 0.268237
CNTN1 contactin 1 0.268237
PPL periplakin 0.267139
CLIC5 chloride intracellular channel 5 0.266408
RAB20 RAB20, member RAS oncogene family 0.264946
BBS9 Bardet-Biedl syndrome 9 0.262755
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 0.261296
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.259837
CAV1 caveolin 1, caveolae protein, 22kDa 0.258381
AVIL advillin 0.257652
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.257652
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.256561
INS insulin 0.254743
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.25438
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.253653
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.253291
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.252564
DMBT1 deleted in malignant brain tumors 1 0.251114
DYSF dysferlin 0.247492
FOXI1 forkhead box I1 0.245685
B2M beta-2-microglobulin 0.244601
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.237401
KIF16B kinesin family member 16B 0.236683
TFRC transferrin receptor 0.233817
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.231315
SLC26A7 solute carrier family 26 (anion exchanger), member 7 0.227397
VIL1 villin 1 0.227041
DBN1 drebrin 1 0.227041
LCT lactase 0.227041
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.225976
LZTS1 leucine zipper, putative tumor suppressor 1 0.22279
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.219265
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.21681
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.21681
CTSE cathepsin E 0.214017
STX8 syntaxin 8 0.214017
SYTL2 synaptotagmin-like 2 0.212974
COL12A1 collagen, type XII, alpha 1 0.211587
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.209513
LUZP6 leucine zipper protein 6 0.204378
CDC42 cell division cycle 42 0.203699
RHAG Rh-associated glycoprotein 0.202009
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.199325
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.19601
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.195025
KRT7 keratin 7, type II 0.186087
IFI30 interferon, gamma-inducible protein 30 0.18516
PANX3 pannexin 3 0.183328
KRT13 keratin 13, type I 0.181823
BYSL bystin-like 0.18093
CLCA2 chloride channel accessory 2 0.177439
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.175188
CAPZB capping protein (actin filament) muscle Z-line, beta 0.175188
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.174361
KIFC3 kinesin family member C3 0.173543
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.17141
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.16935
PANX1 pannexin 1 0.168349
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.167611
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.162763
C5AR2 complement component 5a receptor 2 0.162546
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.161068
RBP3 retinol binding protein 3, interstitial 0.160658
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.159856
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.159462
GSN gelsolin 0.159462
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.159074
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.15776