apical plasma membrane Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The region of the plasma membrane located at the apical end of the cell. (Gene Ontology, GO_0016324)
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Genes

217 proteins localized to the apical plasma membrane cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.663342
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.663342
SLC46A1 solute carrier family 46 (folate transporter), member 1 0.663342
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.663342
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.663342
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.663342
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.663342
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.663342
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.663342
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.663342
AQP2 aquaporin 2 (collecting duct) 0.663342
AQP5 aquaporin 5 0.663342
AKAP7 A kinase (PRKA) anchor protein 7 0.663342
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.663342
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.663342
DUOX1 dual oxidase 1 0.663342
SLC22A18 solute carrier family 22, member 18 0.663342
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 0.663342
CRB3 crumbs family member 3 0.663342
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.663342
AJAP1 adherens junctions associated protein 1 0.663342
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.663342
INADL InaD-like (Drosophila) 0.663342
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.663342
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.663342
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.663342
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.663342
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.663342
CIB1 calcium and integrin binding 1 (calmyrin) 0.663342
DSTYK dual serine/threonine and tyrosine protein kinase 0.663342
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.663342
AQP1 aquaporin 1 (Colton blood group) 0.663342
NOD1 nucleotide-binding oligomerization domain containing 1 0.663342
HYAL2 hyaluronoglucosaminidase 2 0.663342
DPEP1 dipeptidase 1 (renal) 0.663342
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.663342
RAB14 RAB14, member RAS oncogene family 0.663342
GIF gastric intrinsic factor (vitamin B synthesis) 0.663342
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 0.663342
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.663342
TEK TEK tyrosine kinase, endothelial 0.663342
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.663342
MPDZ multiple PDZ domain protein 0.663342
TDGF1 teratocarcinoma-derived growth factor 1 0.663342
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.663342
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.663342
TF transferrin 0.663342
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.663342
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.663342
RHCG Rh family, C glycoprotein 0.663342
SI sucrase-isomaltase (alpha-glucosidase) 0.663342
DPP4 dipeptidyl-peptidase 4 0.663342
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.663342
EPCAM epithelial cell adhesion molecule 0.663342
GPR143 G protein-coupled receptor 143 0.663342
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.663342
LCT lactase 0.663342
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.663342
MGAM maltase-glucoamylase 0.663342
MUC17 mucin 17, cell surface associated 0.663342
PFKM phosphofructokinase, muscle 0.663342
MAL mal, T-cell differentiation protein 0.663342
UMOD uromodulin 0.663342
PARD3 par-3 family cell polarity regulator 0.663342
STX3 syntaxin 3 0.237908
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 0.237908
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.237908
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.237908
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.237908
IL6R interleukin 6 receptor 0.237908
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 0.237908
MARVELD2 MARVEL domain containing 2 0.237908
CD34 CD34 molecule 0.237908
CA4 carbonic anhydrase IV 0.237908
NRG1 neuregulin 1 0.237908
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.237908
THY1 Thy-1 cell surface antigen 0.237908
ADAM17 ADAM metallopeptidase domain 17 0.237908
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.237908
SHROOM4 shroom family member 4 0.237908
MTDH metadherin 0.237908
LRP2 low density lipoprotein receptor-related protein 2 0.237908
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 0.237908
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.237908
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.237908
PODXL podocalyxin-like 0.237908
MUC13 mucin 13, cell surface associated 0.237908
TLR9 toll-like receptor 9 0.237908
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.237908
VANGL2 VANGL planar cell polarity protein 2 0.237908
CAV1 caveolin 1, caveolae protein, 22kDa 0.237908
SHROOM2 shroom family member 2 0.237908
BST2 bone marrow stromal cell antigen 2 0.237908
PLET1 placenta expressed transcript 1 0.237908
PTPRO protein tyrosine phosphatase, receptor type, O 0.237908
RAB17 RAB17, member RAS oncogene family 0.237908
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.237908
AMN amnion associated transmembrane protein 0.237908
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 0.098109
MUC1 mucin 1, cell surface associated 0.098109
SHROOM3 shroom family member 3 0.098109
PTH1R parathyroid hormone 1 receptor 0.098109
ANXA13 annexin A13 0.098109
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.098109
USH2A Usher syndrome 2A (autosomal recessive, mild) 0.098109
PSEN1 presenilin 1 0.098109
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.098109
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.098109
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3 0.098109
PSEN2 presenilin 2 0.098109
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.03318
CLDND1 claudin domain containing 1 0.03318
STXBP3 syntaxin binding protein 3 0.03318
PRKCI protein kinase C, iota 0.03318
KNCN kinocilin 0.03318
PRKCZ protein kinase C, zeta 0.03318
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.03318
MIP major intrinsic protein of lens fiber 0.03318
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.03318
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.03318
EMP2 epithelial membrane protein 2 0.03318
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.03318
NOX4 NADPH oxidase 4 0.03318
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 0.03318
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.03318
AMOTL2 angiomotin like 2 0.03318
AMOTL1 angiomotin like 1 0.03318
LHFPL5 lipoma HMGIC fusion partner-like 5 0.03318
ERBB2 erb-b2 receptor tyrosine kinase 2 0.03318
ERBB3 erb-b2 receptor tyrosine kinase 3 0.03318
CD300LG CD300 molecule-like family member g 0.03318
F2RL2 coagulation factor II (thrombin) receptor-like 2 0.03318
CLDN1 claudin 1 0.03318
CLDN4 claudin 4 0.03318
DSG1 desmoglein 1 0.03318
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.03318
KISS1 KiSS-1 metastasis-suppressor 0.03318
RAB27B RAB27B, member RAS oncogene family 0.03318
RAB27A RAB27A, member RAS oncogene family 0.03318
EZR ezrin 0.03318
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.03318
ANO1 anoctamin 1, calcium activated chloride channel 0.03318
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.03318
GJB6 gap junction protein, beta 6, 30kDa 0.03318
STK39 serine threonine kinase 39 0.03318
ADGRG2 adhesion G protein-coupled receptor G2 0.03318
UPK1B uroplakin 1B 0.03318
OTOA otoancorin 0.03318
OCLN occludin 0.03318
PDPN podoplanin 0.03318
PIP prolactin-induced protein 0.03318
LZTS1 leucine zipper, putative tumor suppressor 1 0.03318
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.03318
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 0.03318
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.03318
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.03318
S100G S100 calcium binding protein G 0.03318
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.03318
TMEM114 transmembrane protein 114 0.03318
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.03318
PROM1 prominin 1 0.03318
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.03318
GJA1 gap junction protein, alpha 1, 43kDa 0.03318
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.03318
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.03318
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.03318
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.03318
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.03318
VAMP3 vesicle-associated membrane protein 3 0.03318
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.03318
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.03318
MSN moesin 0.03318
DDR2 discoidin domain receptor tyrosine kinase 2 0.03318
DSG2 desmoglein 2 0.03318
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.03318
OXTR oxytocin receptor 0.03318
ACY3 aminoacylase 3 0.03318
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.03318
PTK2 protein tyrosine kinase 2 0.03318
PDZK1 PDZ domain containing 1 0.03318
FN1 fibronectin 1 0.03318
MYO1A myosin IA 0.03318
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.03318
CLCN3 chloride channel, voltage-sensitive 3 0.03318
TJP3 tight junction protein 3 0.03318
TJP1 tight junction protein 1 0.03318
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.03318
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.03318
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.03318
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.03318
STC1 stanniocalcin 1 0.03318
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.03318
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.03318
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.03318
EGFR epidermal growth factor receptor 0.03318
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.03318
MYO7A myosin VIIA 0.03318
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.03318
UPK2 uroplakin 2 0.03318
CD9 CD9 molecule 0.03318
GP2 glycoprotein 2 (zymogen granule membrane) 0.03318
UPK3A uroplakin 3A 0.03318
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.03318
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.03318
SPTBN2 spectrin, beta, non-erythrocytic 2 0.03318
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.03318
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.03318
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.03318
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.03318
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.03318
FZD3 frizzled class receptor 3 0.03318
CYBA cytochrome b-245, alpha polypeptide 0.03318
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.03318
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.03318
ADRB2 adrenoceptor beta 2, surface 0.03318
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.03318
AQP8 aquaporin 8 0.03318