apical junction complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. (Gene Ontology, GO_0043296)
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471 proteins co-occuring with the apical junction complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
OCLN occludin 4.62745
TJP1 tight junction protein 1 4.23018
CLDN7 claudin 7 3.56833
CLDN1 claudin 1 3.55128
CLDN5 claudin 5 3.16046
CLDN4 claudin 4 3.01863
CLDN3 claudin 3 2.84339
TJP2 tight junction protein 2 2.65768
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 2.12531
F11R F11 receptor 2.01484
CLDN16 claudin 16 1.99548
MARVELD2 MARVEL domain containing 2 1.96921
CGN cingulin 1.9209
TJP3 tight junction protein 3 1.86211
CLDN8 claudin 8 1.74829
CLDN6 claudin 6 1.71063
CLDN11 claudin 11 1.70199
CLDN14 claudin 14 1.63361
CLDN18 claudin 18 1.62
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 1.58795
CLDN15 claudin 15 1.57016
CLDN2 claudin 2 1.55991
PARD6A par-6 family cell polarity regulator alpha 1.5497
CLDN10 claudin 10 1.50735
CDH5 cadherin 5, type 2 (vascular endothelium) 1.4774
CLDN19 claudin 19 1.4576
INADL InaD-like (Drosophila) 1.45647
CLDN12 claudin 12 1.37962
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 1.36692
GJA1 gap junction protein, alpha 1, 43kDa 1.31627
JAM3 junctional adhesion molecule 3 1.30873
MARVELD3 MARVEL domain containing 3 1.30336
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.29478
MYLK myosin light chain kinase 1.28143
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.25811
MPDZ multiple PDZ domain protein 1.25601
ALB albumin 1.22568
MMP9 matrix metallopeptidase 9 1.20292
RAB13 RAB13, member RAS oncogene family 1.19777
YBX3 Y box binding protein 3 1.13523
CLDN9 claudin 9 1.12603
CD81 CD81 molecule 1.10817
DSP desmoplakin 1.09187
TNF tumor necrosis factor 1.08679
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.06246
AQP4 aquaporin 4 1.04431
SYMPK symplekin 1.0408
JUP junction plakoglobin 1.01883
CTNND1 catenin (cadherin-associated protein), delta 1 1.01734
GRHL2 grainyhead-like 2 (Drosophila) 1.01387
AQP2 aquaporin 2 (collecting duct) 1.00054
DNAH8 dynein, axonemal, heavy chain 8 0.994652
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.984393
CXADR coxsackie virus and adenovirus receptor 0.980501
MYLK3 myosin light chain kinase 3 0.977104
CRB3 crumbs family member 3 0.976619
IGSF5 immunoglobulin superfamily, member 5 0.965993
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.960707
CNTNAP1 contactin associated protein 1 0.95831
AMOT angiomotin 0.942584
VEGFA vascular endothelial growth factor A 0.932658
GUK1 guanylate kinase 1 0.928422
ANGPT1 angiopoietin 1 0.912977
PARD3 par-3 family cell polarity regulator 0.912045
PLEKHA7 pleckstrin homology domain containing, family A member 7 0.868126
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.865826
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.864447
CDC42 cell division cycle 42 0.847451
VCL vinculin 0.846991
MMP2 matrix metallopeptidase 2 0.834138
ICAM1 intercellular adhesion molecule 1 0.830466
EZR ezrin 0.829089
IL1B interleukin 1, beta 0.826336
CLDN17 claudin 17 0.817158
BVES blood vessel epicardial substance 0.815322
MICALL2 MICAL-like 2 0.814405
INS insulin 0.811193
AQP5 aquaporin 5 0.789649
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.775014
LIN7A lin-7 homolog A (C. elegans) 0.773645
DSG2 desmoglein 2 0.772732
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.770907
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.755891
CAV1 caveolin 1, caveolae protein, 22kDa 0.753623
AQP3 aquaporin 3 (Gill blood group) 0.75317
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.748641
ESAM endothelial cell adhesion molecule 0.739614
CLDN25 claudin 25 0.736913
FN1 fibronectin 1 0.732422
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.727941
TLR4 toll-like receptor 4 0.724365
CNTN1 contactin 1 0.717236
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.710579
JAM2 junctional adhesion molecule 2 0.700423
KRT18 keratin 18, type I 0.700423
DPP4 dipeptidyl-peptidase 4 0.682027
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.681155
TFF3 trefoil factor 3 (intestinal) 0.67463
CCL2 chemokine (C-C motif) ligand 2 0.671593
AMOTL1 angiomotin like 1 0.669858
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.658619
PARD6B par-6 family cell polarity regulator beta 0.657326
PDZK1 PDZ domain containing 1 0.652159
ILDR1 immunoglobulin-like domain containing receptor 1 0.652159
TGFB1 transforming growth factor, beta 1 0.646145
EPPIN epididymal peptidase inhibitor 0.645287
CALCOCO2 calcium binding and coiled-coil domain 2 0.644429
CDX2 caudal type homeobox 2 0.644429
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.642286
TLR2 toll-like receptor 2 0.639289
TF transferrin 0.630745
BEND5 BEN domain containing 5 0.624781
BEND3 BEN domain containing 3 0.617982
NISCH nischarin 0.614165
PRSS8 protease, serine, 8 0.60655
RPE65 retinal pigment epithelium-specific protein 65kDa 0.605706
CLMP CXADR-like membrane protein 0.605706
DSG1 desmoglein 1 0.605284
WNK4 WNK lysine deficient protein kinase 4 0.60444
MUC2 mucin 2, oligomeric mucus/gel-forming 0.602752
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.600644
LSR lipolysis stimulated lipoprotein receptor 0.593072
ILDR2 immunoglobulin-like domain containing receptor 2 0.591392
PARD3B par-3 family cell polarity regulator beta 0.588037
TSLP thymic stromal lymphopoietin 0.583012
ANGPT2 angiopoietin 2 0.580504
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.578833
ALPP alkaline phosphatase, placental 0.577164
KNG1 kininogen 1 0.574662
TGFB3 transforming growth factor, beta 3 0.572994
SI sucrase-isomaltase (alpha-glucosidase) 0.572994
ALPPL2 alkaline phosphatase, placental-like 2 0.57008
ALPL alkaline phosphatase, liver/bone/kidney 0.569664
IL10 interleukin 10 0.568001
GJD2 gap junction protein, delta 2, 36kDa 0.564262
PIGR polymeric immunoglobulin receptor 0.563017
DLG4 discs, large homolog 4 (Drosophila) 0.558871
GJB2 gap junction protein, beta 2, 26kDa 0.555559
EGFR epidermal growth factor receptor 0.553905
SOX18 SRY (sex determining region Y)-box 18 0.552251
MAEA macrophage erythroblast attacher 0.54936
F8 coagulation factor VIII, procoagulant component 0.54771
NOS3 nitric oxide synthase 3 (endothelial cell) 0.546472
KRT8 keratin 8, type II 0.544
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.543176
MAPK14 mitogen-activated protein kinase 14 0.536183
CRB2 crumbs family member 2 0.532488
VCAM1 vascular cell adhesion molecule 1 0.530847
MSN moesin 0.52225
ALPI alkaline phosphatase, intestinal 0.519389
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.51694
EXOSC1 exosome component 1 0.515308
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) 0.515308
IL36B interleukin 36, beta 0.515308
DEFB106A defensin, beta 106A 0.515308
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 0.515308
TRIM10 tripartite motif containing 10 0.515308
DEFB129 defensin, beta 129 0.515308
DLG1 discs, large homolog 1 (Drosophila) 0.511233
CGNL1 cingulin-like 1 0.509197
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.509197
EEA1 early endosome antigen 1 0.505944
MYO5B myosin VB 0.505131
CXCL8 chemokine (C-X-C motif) ligand 8 0.500258
FTL ferritin, light polypeptide 0.498231
FTH1 ferritin, heavy polypeptide 1 0.496205
RHOC ras homolog family member C 0.494585
CD79A CD79a molecule, immunoglobulin-associated alpha 0.493775
IL6 interleukin 6 0.488923
SHROOM2 shroom family member 2 0.488923
AQP8 aquaporin 8 0.486096
LRP2 low density lipoprotein receptor-related protein 2 0.480453
SCRIB scribbled planar cell polarity protein 0.476027
AVP arginine vasopressin 0.474822
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.470005
OLFM3 olfactomedin 3 0.468401
TIAM1 T-cell lymphoma invasion and metastasis 1 0.465998
PKP2 plakophilin 2 0.463997
FLG filaggrin 0.454816
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.453621
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.452427
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.452427
DSC2 desmocollin 2 0.448451
KIRREL kin of IRRE like (Drosophila) 0.442896
RDX radixin 0.44052
SCARB1 scavenger receptor class B, member 1 0.436565
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.436565
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.43617
LIN7C lin-7 homolog C (C. elegans) 0.435775
CLN5 ceroid-lipofuscinosis, neuronal 5 0.432618
CTTN cortactin 0.430253
RAB11A RAB11A, member RAS oncogene family 0.426318
RPTN repetin 0.424745
KRT7 keratin 7, type II 0.424353
IL13 interleukin 13 0.422389
MAP2K2 mitogen-activated protein kinase kinase 2 0.41886
VWF von Willebrand factor 0.417294
MPO myeloperoxidase 0.414164
KCNK17 potassium channel, two pore domain subfamily K, member 17 0.414164
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.413382
LLGL2 lethal giant larvae homolog 2 (Drosophila) 0.41143
DNTT DNA nucleotidylexotransferase 0.410259
RLBP1 retinaldehyde binding protein 1 0.407919
GFAP glial fibrillary acidic protein 0.40714
MGAM maltase-glucoamylase 0.40675
NEXN nexilin (F actin binding protein) 0.405193
ESPN espin 0.40247
SYNPO synaptopodin 0.402081
CLDN22 claudin 22 0.398587
STK11 serine/threonine kinase 11 0.397811
ACE angiotensin I converting enzyme 0.397811
GJB1 gap junction protein, beta 1, 32kDa 0.397423
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.396648
ATP11A ATPase, class VI, type 11A 0.393936
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.393936
HBA1 hemoglobin, alpha 1 0.393936
ERBB2 erb-b2 receptor tyrosine kinase 2 0.392388
IGF1 insulin-like growth factor 1 (somatomedin C) 0.389682
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.388137
HBA2 hemoglobin, alpha 2 0.388137
TFRC transferrin receptor 0.385051
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.383895
TG thyroglobulin 0.380045
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.37966
AMOTL2 angiomotin like 2 0.378507
ZEB1 zinc finger E-box binding homeobox 1 0.376586
KRT20 keratin 20, type I 0.37505
MARK2 MAP/microtubule affinity-regulating kinase 2 0.373132
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.372749
TERT telomerase reverse transcriptase 0.371216
PTH parathyroid hormone 0.370833
GJC1 gap junction protein, gamma 1, 45kDa 0.369301
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 0.368536
AQP1 aquaporin 1 (Colton blood group) 0.366241
FAM136A family with sequence similarity 136, member A 0.365859
PLAT plasminogen activator, tissue 0.363185
CD44 CD44 molecule (Indian blood group) 0.359371
CSN1S1 casein alpha s1 0.358609
JUN jun proto-oncogene 0.356705
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.354042
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.352901
FGF2 fibroblast growth factor 2 (basic) 0.352522
CLDN20 claudin 20 0.351382
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.351002
YBX1 Y box binding protein 1 0.350622
KLF4 Kruppel-like factor 4 (gut) 0.347967
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.346829
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.345692
CCDC85C coiled-coil domain containing 85C 0.344935
S100A4 S100 calcium binding protein A4 0.343421
GDNF glial cell derived neurotrophic factor 0.343042
FGFBP3 fibroblast growth factor binding protein 3 0.341151
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.340395
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.340017
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.340017
CLCNKB chloride channel, voltage-sensitive Kb 0.339639
SLCO1A2 solute carrier organic anion transporter family, member 1A2 0.339261
TACSTD2 tumor-associated calcium signal transducer 2 0.337373
KRT3 keratin 3, type II 0.336996
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.336619
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.336619
TMEM204 transmembrane protein 204 0.335864
AQP6 aquaporin 6, kidney specific 0.335487
HNF4A hepatocyte nuclear factor 4, alpha 0.334356
TLR5 toll-like receptor 5 0.332472
CD4 CD4 molecule 0.332095
YAP1 Yes-associated protein 1 0.330966
HAPLN3 hyaluronan and proteoglycan link protein 3 0.329461
NOD2 nucleotide-binding oligomerization domain containing 2 0.324576
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.32345
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.320451
NOTCH1 notch 1 0.319702
SNAI1 snail family zinc finger 1 0.318953
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.318205
KRT19 keratin 19, type I 0.31783
IVL involucrin 0.316708
RAB3D RAB3D, member RAS oncogene family 0.31596
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.31596
CDSN corneodesmosin 0.312597
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.311851
VASP vasodilator-stimulated phosphoprotein 0.311105
LCT lactase 0.309986
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.308122
UPK2 uroplakin 2 0.308122
UPK3A uroplakin 3A 0.305888
SELE selectin E 0.305143
SLC35F2 solute carrier family 35, member F2 0.304771
AGTR2 angiotensin II receptor, type 2 0.304771
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.302168
SHROOM3 shroom family member 3 0.299569
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.299197
EHF ets homologous factor 0.298826
ZEB2 zinc finger E-box binding homeobox 2 0.298084
ANPEP alanyl (membrane) aminopeptidase 0.297713
VSIG1 V-set and immunoglobulin domain containing 1 0.297713
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.29586
MRPS7 mitochondrial ribosomal protein S7 0.292897
MYO9B myosin IXB 0.292527
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.292157
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.290678
HBEGF heparin-binding EGF-like growth factor 0.289199
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.288829
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.286983
FGF7 fibroblast growth factor 7 0.282189
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.280716
SORBS1 sorbin and SH3 domain containing 1 0.279612
TIMP1 TIMP metallopeptidase inhibitor 1 0.278509
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.275569
GSTA4 glutathione S-transferase alpha 4 0.271533
EVL Enah/Vasp-like 0.270434
GSTA2 glutathione S-transferase alpha 2 0.270068
BSND barttin CLCNK-type chloride channel accessory beta subunit 0.269701
WWC1 WW and C2 domain containing 1 0.267871
MUC16 mucin 16, cell surface associated 0.266774
UBN1 ubinuclein 1 0.264946
RAB25 RAB25, member RAS oncogene family 0.262755
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.262755
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.262025
GPR158 G protein-coupled receptor 158 0.259837
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.259109
CCND1 cyclin D1 0.258016
DCHS1 dachsous cadherin-related 1 0.255834
LALBA lactalbumin, alpha- 0.255107
SMAD2 SMAD family member 2 0.253653
ECT2 epithelial cell transforming 2 0.253653
WDR66 WD repeat domain 66 0.253291
SMAD4 SMAD family member 4 0.252927
FGF1 fibroblast growth factor 1 (acidic) 0.251839
ARHGAP17 Rho GTPase activating protein 17 0.251114
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.251114
GSTA3 glutathione S-transferase alpha 3 0.250751
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.250389
ACPP acid phosphatase, prostate 0.250389
EMP1 epithelial membrane protein 1 0.246769
GSTA1 glutathione S-transferase alpha 1 0.246769
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.246046
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.245685
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.245685
ILK integrin-linked kinase 0.244601
RND3 Rho family GTPase 3 0.243879
EPHA5 EPH receptor A5 0.242076
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.240996
GPR155 G protein-coupled receptor 155 0.240996
EPB41 erythrocyte membrane protein band 4.1 0.240276
DNM2 dynamin 2 0.239197
SYBU syntabulin (syntaxin-interacting) 0.238119
NFASC neurofascin 0.237401
VASH1 vasohibin 1 0.237042
PTPRD protein tyrosine phosphatase, receptor type, D 0.237042
MYO5C myosin VC 0.236683
CD2AP CD2-associated protein 0.234533
PDGFC platelet derived growth factor C 0.234533
PAX6 paired box 6 0.233459
RICTOR RPTOR independent companion of MTOR, complex 2 0.233101
MUC1 mucin 1, cell surface associated 0.233101
MMP3 matrix metallopeptidase 3 0.230958
PTEN phosphatase and tensin homolog 0.229888
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.229532
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.229176
CCR2 chemokine (C-C motif) receptor 2 0.229176
TRAF4 TNF receptor-associated factor 4 0.229176
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.227397
EPHA2 EPH receptor A2 0.225976
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.223143
IGSF11 immunoglobulin superfamily, member 11 0.22279
MAPK9 mitogen-activated protein kinase 9 0.222436
ARHGAP30 Rho GTPase activating protein 30 0.220673
KLF2 Kruppel-like factor 2 0.220673
GJB3 gap junction protein, beta 3, 31kDa 0.219617
DSC1 desmocollin 1 0.218914
FAT4 FAT atypical cadherin 4 0.218563
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.218563
EPHA1 EPH receptor A1 0.218563
TSPO translocator protein (18kDa) 0.217861
FSHR follicle stimulating hormone receptor 0.217861
FOXP3 forkhead box P3 0.21716
F2RL3 coagulation factor II (thrombin) receptor-like 3 0.21646
ELP5 elongator acetyltransferase complex subunit 5 0.216111
WASL Wiskott-Aldrich syndrome-like 0.216111
KRT14 keratin 14, type I 0.214366
GATA6 GATA binding protein 6 0.213322
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.212974
PLS1 plastin 1 0.211933
EPHA7 EPH receptor A7 0.211587
MIR212 microRNA 212 0.210549
POU3F4 POU class 3 homeobox 4 0.209513
PGF placental growth factor 0.208825
TAC1 tachykinin, precursor 1 0.208137
MET MET proto-oncogene, receptor tyrosine kinase 0.207108
BSPRY B-box and SPRY domain containing 0.205399
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.205399
MYD88 myeloid differentiation primary response 88 0.204378
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.202346
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 0.202009
MMP7 matrix metallopeptidase 7 0.201335
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 0.198991
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.198325
DSC3 desmocollin 3 0.197662
C4B complement component 4B (Chido blood group) 0.197662
TTR transthyretin 0.196669
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.196339
TAT tyrosine aminotransferase 0.195353
CERCAM cerebral endothelial cell adhesion molecule 0.193719
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.193394
CAT catalase 0.193394
ESRP1 epithelial splicing regulatory protein 1 0.19307
EFNA1 ephrin-A1 0.192746
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.192423
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.1921
FRMPD2 FERM and PDZ domain containing 2 0.191777
RCCD1 RCC1 domain containing 1 0.191456
MOG myelin oligodendrocyte glycoprotein 0.191456
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.191135
SOD2 superoxide dismutase 2, mitochondrial 0.185469
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.183025
DEFB106B defensin, beta 106B 0.183025
TGFBR1 transforming growth factor, beta receptor 1 0.182723
ARHGAP31 Rho GTPase activating protein 31 0.18093
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.179459
THBS1 thrombospondin 1 0.178877
ZHX2 zinc fingers and homeoboxes 2 0.178299
MAL mal, T-cell differentiation protein 0.178299
ETV5 ets variant 5 0.178011
MYO7A myosin VIIA 0.177724
SST somatostatin 0.177439
MICALL1 MICAL-like 1 0.177439
PTPRJ protein tyrosine phosphatase, receptor type, J 0.177154
MAPK3 mitogen-activated protein kinase 3 0.176587
A4GALT alpha 1,4-galactosyltransferase 0.175466
PKN2 protein kinase N2 0.174635
CASR calcium-sensing receptor 0.174361
CLRN1 clarin 1 0.173003
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.171937
PDGFD platelet derived growth factor D 0.17141
TMEM47 transmembrane protein 47 0.170629
MYO6 myosin VI 0.170371
CDH18 cadherin 18, type 2 0.169604
CREB5 cAMP responsive element binding protein 5 0.169099
STX3 syntaxin 3 0.169099
GJB6 gap junction protein, beta 6, 30kDa 0.168101
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.166643
DSG3 desmoglein 3 0.166167
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.165463
FLOT1 flotillin 1 0.165231
EPS8 epidermal growth factor receptor pathway substrate 8 0.165231
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 0.165
OVOL1 ovo-like zinc finger 1 0.165
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.16477
BICC1 BicC family RNA binding protein 1 0.164542
PCNA proliferating cell nuclear antigen 0.164315
TIMP2 TIMP metallopeptidase inhibitor 2 0.163865
CD24 CD24 molecule 0.1632
PRKD1 protein kinase D1 0.1632
CAB39 calcium binding protein 39 0.16298
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.162763
LIX1 Lix1 homolog (chicken) 0.162763
TLR1 toll-like receptor 1 0.162546
EPHA3 EPH receptor A3 0.16233
PDZD3 PDZ domain containing 3 0.16233
CCL11 chemokine (C-C motif) ligand 11 0.162117
TFF2 trefoil factor 2 0.161275
GDF9 growth differentiation factor 9 0.160863
DFNB59 deafness, autosomal recessive 59 0.160658
DKKL1 dickkopf-like 1 0.159856
BCHE butyrylcholinesterase 0.159856
TMEM43 transmembrane protein 43 0.159658
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.15776
GCG glucagon 0.157397
GJA5 gap junction protein, alpha 5, 40kDa 0.157039
KRT5 keratin 5, type II 0.156863
MUC6 mucin 6, oligomeric mucus/gel-forming 0.156513