ap-2 adaptor complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle; vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). (Gene Ontology, GO_0030122)
External Link http://amigo.geneontology.org/amigo/term/GO:0030122
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Genes

11 proteins localized to the ap-2 adaptor complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
EGFR epidermal growth factor receptor
EPS15 epidermal growth factor receptor pathway substrate 15
LDLRAP1 low density lipoprotein receptor adaptor protein 1
PICALM phosphatidylinositol binding clathrin assembly protein
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1
TBC1D5 TBC1 domain family, member 5