ap-2 adaptor complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle; vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). (Gene Ontology, GO_0030122)
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4 proteins localized to the ap-2 adaptor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.663342
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.663342
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.237908
EPS15 epidermal growth factor receptor pathway substrate 15 0.03318